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mTORC1 signaling and regulation of pancreatic β-cell mass.
Blandino-Rosano M, Chen AY, Scheys JO, Alejandro EU, Gould AP, Taranukha T, Elghazi L, Cras-Méneur C, Bernal-Mizrachi E. Blandino-Rosano M, et al. Among authors: cras meneur c. Cell Cycle. 2012 May 15;11(10):1892-902. doi: 10.4161/cc.20036. Epub 2012 May 15. Cell Cycle. 2012. PMID: 22544327 Free PMC article. Review.
Hyperglucagonemia in an animal model of insulin- deficient diabetes: what therapy can improve it?
Barbetti F, Colombo C, Haataja L, Cras-Méneur C, Bernardini S, Arvan P. Barbetti F, et al. Among authors: cras meneur c. Clin Diabetes Endocrinol. 2016 May 2;2:11. doi: 10.1186/s40842-016-0029-5. eCollection 2016. Clin Diabetes Endocrinol. 2016. PMID: 28702245 Free PMC article.
Akita mice carry a toxic-gain-of- function Ins2 gene mutation encoding proinsulin-C(A7)Y, similar to that described in human Mutant Ins-gene induced Diabetes of Youth, which decreases intra-islet insulin. ...The possibility that loss of intra-islet suppression of alpha-cel …
Akita mice carry a toxic-gain-of- function Ins2 gene mutation encoding proinsulin-C(A7)Y, similar to that described in human Mutant I …
Inhibition of Foxo1 protects pancreatic islet beta-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis.
Martinez SC, Tanabe K, Cras-Méneur C, Abumrad NA, Bernal-Mizrachi E, Permutt MA. Martinez SC, et al. Among authors: cras meneur c. Diabetes. 2008 Apr;57(4):846-59. doi: 10.2337/db07-0595. Epub 2008 Jan 3. Diabetes. 2008. PMID: 18174526
Microarray analysis revealed that fatty acid induction of gene expression was in most cases reversed by Adv-DNFoxo, including the proapoptotic transcription factor CHOP (C/EBP [CCAAT/enhancer binding protein] homologous protein). CONCLUSIONS: Early induction of JNK and Fox …
Microarray analysis revealed that fatty acid induction of gene expression was in most cases reversed by Adv-DNFoxo, including the proapoptot …