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58 results

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Page 1
High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics.
Gérard A, Woolfe A, Mottet G, Reichen M, Castrillon C, Menrath V, Ellouze S, Poitou A, Doineau R, Briseno-Roa L, Canales-Herrerias P, Mary P, Rose G, Ortega C, Delincé M, Essono S, Jia B, Iannascoli B, Richard-Le Goff O, Kumar R, Stewart SN, Pousse Y, Shen B, Grosselin K, Saudemont B, Sautel-Caillé A, Godina A, McNamara S, Eyer K, Millot GA, Baudry J, England P, Nizak C, Jensen A, Griffiths AD, Bruhns P, Brenan C. Gérard A, et al. Among authors: poitou a. Nat Biotechnol. 2020 Jun;38(6):715-721. doi: 10.1038/s41587-020-0466-7. Epub 2020 Mar 30. Nat Biotechnol. 2020. PMID: 32231335 Free article.
A novel pathogenic variant in MRAP2 in an obese patient with successful outcome of bariatric surgery.
Gatta-Cherifi B, Laboye A, Gronnier C, Monsaingeon-Henry M, Meulebrouck S, Baron M, Bertin F, Pupier E, Cambos S, Poitou C, Beyec-Le Bihan JL, Bonnefond A. Gatta-Cherifi B, et al. Among authors: poitou c. Eur J Endocrinol. 2023 Oct 17;189(4):K15-K18. doi: 10.1093/ejendo/lvad132. Eur J Endocrinol. 2023. PMID: 37888144 Free article.
A new heterozygous variant in MRAP2 (NM_138409.4: c.154G>C/p.G52R) variant was identified in the patient DNA. Functional assessment confirmed that this new variant was pathogenic. ...
A new heterozygous variant in MRAP2 (NM_138409.4: c.154G>C/p.G52R) variant was identified in the patient DNA. Functional as …
MC4R agonism promotes durable weight loss in patients with leptin receptor deficiency.
Clément K, Biebermann H, Farooqi IS, Van der Ploeg L, Wolters B, Poitou C, Puder L, Fiedorek F, Gottesdiener K, Kleinau G, Heyder N, Scheerer P, Blume-Peytavi U, Jahnke I, Sharma S, Mokrosinski J, Wiegand S, Müller A, Weiß K, Mai K, Spranger J, Grüters A, Blankenstein O, Krude H, Kühnen P. Clément K, et al. Among authors: poitou c. Nat Med. 2018 May;24(5):551-555. doi: 10.1038/s41591-018-0015-9. Epub 2018 May 7. Nat Med. 2018. PMID: 29736023 Clinical Trial.
Senescence-associated β-galactosidase in subcutaneous adipose tissue associates with altered glycaemic status and truncal fat in severe obesity.
Rouault C, Marcelin G, Adriouch S, Rose C, Genser L, Ambrosini M, Bichet JC, Zhang Y, Marquet F, Aron-Wisnewsky J, Poitou C, André S, Dérumeaux G, Guerre-Millo M, Clément K. Rouault C, et al. Among authors: poitou c. Diabetologia. 2021 Jan;64(1):240-254. doi: 10.1007/s00125-020-05307-0. Epub 2020 Oct 30. Diabetologia. 2021. PMID: 33125520 Clinical Trial.
Several factors, including insulin-like growth factor binding protein 3 (IGFBP3), plasminogen activator inhibitor 1 (PAI1), C-C motif chemokine ligand 2 (CCL2) and IL-6, were upregulated in subcutaneous adipose tissue in relation with SA-beta-gal (p for linear trend …
Several factors, including insulin-like growth factor binding protein 3 (IGFBP3), plasminogen activator inhibitor 1 (PAI1), C-C
The d.
Nikulin VN, Boudard A, Clajus M, Fabbro B, Garçon M, Kessler RS, Lytkin LK, Mayer B, Nefkens BM, Plouin F, Poitou J, Tomasi-Gustafsson E, van Oers WT, White D, Wilkin C. Nikulin VN, et al. Among authors: poitou j. Phys Rev C Nucl Phys. 1996 Oct;54(4):1732-1740. doi: 10.1103/physrevc.54.1732. Phys Rev C Nucl Phys. 1996. PMID: 9971520 No abstract available.
The effect of morbid obesity on morphine glucuronidation.
Lloret-Linares C, Luo H, Rouquette A, Labat L, Poitou C, Tordjman J, Bouillot JL, Mouly S, Scherrmann JM, Bergmann JF, Declèves X. Lloret-Linares C, et al. Among authors: poitou c. Pharmacol Res. 2017 Apr;118:64-70. doi: 10.1016/j.phrs.2016.08.031. Epub 2016 Sep 5. Pharmacol Res. 2017. PMID: 27609660
The pharmacokinetics (PK) of oral morphine (30mg), morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G) was performed in patients before (n=25; mean BMI=43.2 (35.4-61.9)kg/m(2)), 7-15days (n=16) and 6 months after RYGB (n=19; mean BMI=32.3 (25.4-46.0)kg/m(2)). Morphine …
The pharmacokinetics (PK) of oral morphine (30mg), morphine-3-glucuronide (M3G) and morphine-6-glucuronide (M6G) was performed in patients b …
Author Correction: High-throughput single-cell activity-based screening and sequencing of antibodies using droplet microfluidics.
Gérard A, Woolfe A, Mottet G, Reichen M, Castrillon C, Menrath V, Ellouze S, Poitou A, Doineau R, Briseno-Roa L, Canales-Herrerias P, Mary P, Rose G, Ortega C, Delincé M, Essono S, Jia B, Iannascoli B, Richard-Le Goff O, Kumar R, Stewart SN, Pousse Y, Shen B, Grosselin K, Saudemont B, Sautel-Caillé A, Godina A, McNamara S, Eyer K, Millot GA, Baudry J, England P, Nizak C, Jensen A, Griffiths AD, Bruhns P, Brenan C. Gérard A, et al. Among authors: poitou a. Nat Biotechnol. 2020 Jun;38(6):756. doi: 10.1038/s41587-020-0563-7. Nat Biotechnol. 2020. PMID: 32444853
Potential contribution of adipose tissue to elevated serum cystatin C in human obesity.
Naour N, Fellahi S, Renucci JF, Poitou C, Rouault C, Basdevant A, Dutour A, Alessi MC, Bastard JP, Clément K, Guerre-Millo M. Naour N, et al. Among authors: poitou c. Obesity (Silver Spring). 2009 Dec;17(12):2121-6. doi: 10.1038/oby.2009.96. Epub 2009 Apr 9. Obesity (Silver Spring). 2009. PMID: 19360013 Free article.
Serum cystatin C is elevated in obese subjects of both genders, independently of reduced eGFR. Cystatin C mRNA is expressed in subcutaneous and omental adipose tissue, at twice higher levels in nonadipose than in adipose cells. Gene expression and cystatin C
Serum cystatin C is elevated in obese subjects of both genders, independently of reduced eGFR. Cystatin C mRNA is expressed in …
Mucosal-associated invariant T (MAIT) cells are depleted and prone to apoptosis in cardiometabolic disorders.
Touch S, Assmann KE, Aron-Wisnewsky J, Marquet F, Rouault C, Fradet M, Mosbah H, Consortium M, Isnard R, Helft G, Lehuen A, Poitou C, Clément K, André S; MetaCardis Consortium. Touch S, et al. Among authors: poitou c. FASEB J. 2018 Apr 27:fj201800052RR. doi: 10.1096/fj.201800052RR. Online ahead of print. FASEB J. 2018. PMID: 29957059
E., Aron-Wisnewsky, J., Marquet, F., Rouault, C., Fradet, M., Mosbah, H., MetaCardis Consortium, Isnard, R., Helft, G., Lehuen, A., Poitou, C., Clement, K., Andre, S. ...
E., Aron-Wisnewsky, J., Marquet, F., Rouault, C., Fradet, M., Mosbah, H., MetaCardis Consortium, Isnard, R., Helft, G., Lehuen, A., P …
58 results