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191 results

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Management of Latent Autoimmune Diabetes in Adults: A Consensus Statement From an International Expert Panel.
Buzzetti R, Tuomi T, Mauricio D, Pietropaolo M, Zhou Z, Pozzilli P, Leslie RD. Buzzetti R, et al. Diabetes. 2020 Oct;69(10):2037-2047. doi: 10.2337/dbi20-0017. Epub 2020 Aug 26. Diabetes. 2020. PMID: 32847960 Free PMC article.
A substantial proportion of patients with adult-onset diabetes share features of both type 1 diabetes (T1D) and type 2 diabetes (T2D). These individuals, at diagnosis, clinically resemble T2D patients by not requiring insulin treatment, yet they have i …
A substantial proportion of patients with adult-onset diabetes share features of both type 1 diabetes (T1D) and type …
Utility of Fasting C-Peptide for the Diagnostic Differentiation of Patients with Type 1, Type 2 Diabetes, MODY, and LADA.
Alemán-Contreras R, Gómez-Díaz RA, Noyola-García ME, Mondragón-González R, Wacher N, Ferreira-Hermosillo A. Alemán-Contreras R, et al. Life (Basel). 2024 Apr 25;14(5):550. doi: 10.3390/life14050550. Life (Basel). 2024. PMID: 38792571 Free PMC article.
We recorded anthropometric measurements, biochemical profiles, and antidiabetic treatment and determined C-peptide, anti-GAD65, and anti-IA2 antibodies. RESULTS: C-peptide concentration differed significantly among populations (T1D: 0.2 ng/mL; T …
We recorded anthropometric measurements, biochemical profiles, and antidiabetic treatment and determined C-peptide, anti-GAD65 …
GAD65 autoimmunity-clinical studies.
Uibo R, Lernmark A. Uibo R, et al. Adv Immunol. 2008;100:39-78. doi: 10.1016/S0065-2776(08)00803-1. Adv Immunol. 2008. PMID: 19111163 Review.
Type 1 diabetes (T1D) in children and particularly in teenagers and adults is strongly associated with autoreactivity to the Mr 65,000 isoform of glutamic acid decarboxylase (GAD65). ...GAD65 autoantibodies predict conversion to insulin dependence when present in pa …
Type 1 diabetes (T1D) in children and particularly in teenagers and adults is strongly associated with autoreactivity to the M …
Unveiling the Therapeutic Potential of the Second-Generation Incretin Analogs Semaglutide and Tirzepatide in Type 1 Diabetes and Latent Autoimmune Diabetes in Adults.
Infante M, Silvestri F, Padilla N, Pacifici F, Pastore D, Pinheiro MM, Caprio M, Tesauro M, Fabbri A, Novelli G, Alejandro R, De Lorenzo A, Ricordi C, Della-Morte D. Infante M, et al. J Clin Med. 2025 Feb 15;14(4):1303. doi: 10.3390/jcm14041303. J Clin Med. 2025. PMID: 40004833 Free PMC article. Review.
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the immune-mediated destruction of insulin-producing pancreatic beta cells, resulting in the lifelong need for exogenous insulin. ...In this context, the term "double diabetes" has been coined …
Type 1 diabetes mellitus (T1D) is a chronic autoimmune disease caused by the immune-mediated destruction of insulin-producing …
LADA: A Type of Diabetes in its Own Right?
Grill V. Grill V. Curr Diabetes Rev. 2019;15(3):174-177. doi: 10.2174/1573399814666180716150905. Curr Diabetes Rev. 2019. PMID: 30009711 Review.
Latent Autoimmune Diabetes in the Adult, LADA has been investigated less than "classical" type 1 and type 2 diabetes and the criteria for and the relevance of a LADA diagnosis have been challenged. ...Yet, there appears to be clear clinic …
Latent Autoimmune Diabetes in the Adult, LADA has been investigated less than "classical" type 1 and type 2 …
Increased spontaneous CCL2 (MCP-1) and CCL5 (RANTES) secretion in vitro in LADA compared to type 1 diabetes and type 2 diabetes: Action LADA 14.
Ooms M, Strom A, Strassburger K, Menart B, Leslie RD, Schloot NC. Ooms M, et al. Diabetes Metab Res Rev. 2021 Oct;37(7):e3431. doi: 10.1002/dmrr.3431. Epub 2021 Jan 16. Diabetes Metab Res Rev. 2021. PMID: 33369072
AIMS: Immune-mediated type 1 diabetes (T1D) in adulthood and latent autoimmune diabetes in adults (LADA) share similar pathological mechanisms but differ clinically in disease progression. ...Upon stimulation with pIA2 the secretion of CCL2 in LADA was …
AIMS: Immune-mediated type 1 diabetes (T1D) in adulthood and latent autoimmune diabetes in adults (LADA) share similar …
Call for Standardization of C-Peptide Measurement.
Schleicher E, Kabytaev K, Nauck M, Müller-Wieland D, Peter A, Little RR, Heinemann L. Schleicher E, et al. J Diabetes Sci Technol. 2025 Aug 8:19322968251362848. doi: 10.1177/19322968251362848. Online ahead of print. J Diabetes Sci Technol. 2025. PMID: 40781799 Free PMC article. Review.
Furthermore, C-peptide assists in the prediction of therapeutic response and guiding therapeutic decisions. To support diabetes classification, the American Diabetes Association (ADA) and the European Association for the Study of Diabetes (EASD) have recently introd …
Furthermore, C-peptide assists in the prediction of therapeutic response and guiding therapeutic decisions. To support diabete …
UNVEILING LADA: PREVALENCE AND CHARACTERISTICS AMONG TYPE 2 DIABETIC PATIENTS IN PORT SUDAN, SUDAN.
Elebaid A, Khalid M, Saeed A, Osman H, Mostafa A, Abdelmola A, Ali E, Algarni A, Ismail M, Mahagoub M, Abdalhabib E, Abdelhadi M, Khudoykulova F, Alfeel A, Ismail M. Elebaid A, et al. Georgian Med News. 2025 May;(362):122-128. Georgian Med News. 2025. PMID: 40737658
BACKGROUND: The intermediate type of diabetes, known as latent autoimmune diabetes in adults (LADA), has traits in common with both type 1 and type 2 diabetic mellitus (T2DM). ...SPSS version 26 was used for statistical analysis, and p&lt …
BACKGROUND: The intermediate type of diabetes, known as latent autoimmune diabetes in adults (LADA), has traits in common with …
Evidence reviews for diagnosis of diabetes: Type 1 diabetes in adults: diagnosis and management: Evidence review C.
[No authors listed] [No authors listed] London: National Institute for Health and Care Excellence (NICE); 2022 Mar. London: National Institute for Health and Care Excellence (NICE); 2022 Mar. PMID: 35593767 Free Books & Documents. Review.
Whilst clinical characteristics (e.g., age at presentation, BMI, and time to insulin treatment from presentation) have often been used for diagnosis, the age and BMI of people living with type 1 and type 2 diabetes now overlap to a greater degree. Ther …
Whilst clinical characteristics (e.g., age at presentation, BMI, and time to insulin treatment from presentation) have often been used for d …
Variable frequencies of peripheral T-lymphocyte subsets in the diabetes spectrum from type 1 diabetes through latent autoimmune diabetes in adults (LADA) to type 2 diabetes.
Tan T, Xiang Y, Deng C, Cao C, Ren Z, Huang G, Zhou Z. Tan T, et al. Front Immunol. 2022 Aug 24;13:974864. doi: 10.3389/fimmu.2022.974864. eCollection 2022. Front Immunol. 2022. PMID: 36091068 Free PMC article.
T lymphocytes are key players in the pathogenesis of autoimmune diabetes. We recruited subjects with T1D (n=81), LADA (n=82), T2D (n=95) and NGT (n=218) and analyzed the percentages of T-lymphocyte subsets, including T helper 1 (Th1), T helper 2 (Th2), T help …
T lymphocytes are key players in the pathogenesis of autoimmune diabetes. We recruited subjects with T1D (n=81), LADA (n=82), T2D (n= …
191 results