C3 glomerulopathy - understanding a rare complement-driven renal disease.
Nat Rev Nephrol. 2019.
PMID: 30692664
Free PMC article.
Review.
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The following term was not found in PubMed: Glomerulopathy-Understanding
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C3 glomerulopathy - understanding a rare complement-driven renal disease.
Smith RJH, Appel GB, Blom AM, Cook HT, D'Agati VD, Fakhouri F, Fremeaux-Bacchi V, Józsi M, Kavanagh D, Lambris JD, Noris M, Pickering MC, Remuzzi G, de Córdoba SR, Sethi S, Van der Vlag J, Zipfel PF, Nester CM.
Smith RJH, et al.
Nat Rev Nephrol. 2019 Mar;15(3):129-143. doi: 10.1038/s41581-018-0107-2.
Nat Rev Nephrol. 2019.
PMID: 30692664
Free PMC article.
Review.
The C3 glomerulopathies are a group of rare kidney diseases characterized by complement dysregulation occurring in the fluid phase and in the glomerular microenvironment, which results in prominent complement C3 deposition in kidney biops …
The C3 glomerulopathies are a group of rare kidney diseases characterized by complement dysregulation occurring …
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Development and validation of a nomogram to predict kidney survival at baseline in patients with C3 glomerulopathy.
Caravaca-Fontán F, Rivero M, Cavero T, Díaz-Encarnación M, Cabello V, Ariceta G, Quintana LF, Marco H, Barros X, Ramos N, Rodríguez-Mendiola N, Cruz S, Fernández-Juárez G, Rodríguez A, Pérez de José A, Rabasco C, Rodado R, Fernández L, Pérez-Gómez V, Ávila A, Bravo L, Espinosa N, Allende N, Sanchez de la Nieta MD, Rodríguez E, Olea T, Melgosa M, Huerta A, Miquel R, Mon C, Fraga G, de Lorenzo A, Draibe J, González F, Shabaka A, López-Rubio ME, Fenollosa MÁ, Martín-Penagos L, Da Silva I, Alonso Titos J, Rodríguez de Córdoba S, Goicoechea de Jorge E, Praga M.
Caravaca-Fontán F, et al.
Clin Kidney J. 2022 Apr 28;15(9):1737-1746. doi: 10.1093/ckj/sfac108. eCollection 2022 Sep.
Clin Kidney J. 2022.
PMID: 36003665
Free PMC article.
BACKGROUND: C3 glomerulopathy is a rare and heterogeneous complement-driven disease. It is often challenging to accurately predict in clinical practice the individual kidney prognosis at baseline. ...CONCLUSIONS: We constructed and valida …
BACKGROUND: C3 glomerulopathy is a rare and heterogeneous complement-driven disease. It is often challeng …
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Gain-of-Function Mutations R249C and S250C in Complement C2 Protein Increase C3 Deposition in the Presence of C-Reactive Protein.
Urban A, Kowalska D, Stasiłojć G, Kuźniewska A, Skrobińska A, Arjona E, Alonso EC, Fenollosa Segarra MÁ, Jongerius I, Spaapen R, Satchell S, Thiel M, Ołdziej S, Rodriguez de Córdoba S, Okrój M.
Urban A, et al.
Front Immunol. 2021 Nov 25;12:724361. doi: 10.3389/fimmu.2021.724361. eCollection 2021.
Front Immunol. 2021.
PMID: 34899688
Free PMC article.
The impairment of the alternative complement pathway contributes to rare kidney diseases such as atypical hemolytic uremic syndrome (aHUS) and C3 glomerulopathy (C3G). ...Our data justify the inclusion of classical pathway genes in the genetic analysis …
The impairment of the alternative complement pathway contributes to rare kidney diseases such as atypical hemolytic ure …
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