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Page 1
The Clinicogenomic Landscape of Induction Failure in Childhood and Young Adult T-Cell Acute Lymphoblastic Leukemia.
O'Connor D, Demeulemeester J, Conde L, Kirkwood A, Fung K, Papaleonidopoulou F, Bloye G, Farah N, Rahman S, Hancock J, Bateman C, Inglott S, Mee J, Herrero J, Van Loo P, Moorman AV, Vora A, Mansour MR. O'Connor D, et al. J Clin Oncol. 2023 Jul 1;41(19):3545-3556. doi: 10.1200/JCO.22.02734. Epub 2023 Apr 25. J Clin Oncol. 2023. PMID: 37098241 Free PMC article.
Aberrant paracrine signalling for bone remodelling underlies the mutant histone-driven giant cell tumour of bone.
Cottone L, Ligammari L, Lee HM, Knowles HJ, Henderson S, Bianco S, Davies C, Strauss S, Amary F, Leite AP, Tirabosco R, Haendler K, Schultze JL, Herrero J, O'Donnell P, Grigoriadis AE, Salomoni P, Flanagan AM. Cottone L, et al. Cell Death Differ. 2022 Dec;29(12):2459-2471. doi: 10.1038/s41418-022-01031-x. Epub 2022 Aug 3. Cell Death Differ. 2022. PMID: 36138226 Free PMC article.
A population of naive-like CD4+ T cells stably polarized to the TH 1 lineage.
Lo JW, de Mucha MV, Henderson S, Roberts LB, Constable LE, Garrido-Mesa N, Hertweck A, Stolarczyk E, Houlder EL, Jackson I, MacDonald AS, Powell N, Neves JF, Howard JK, Jenner RG, Lord GM. Lo JW, et al. Eur J Immunol. 2022 Apr;52(4):566-581. doi: 10.1002/eji.202149228. Epub 2022 Feb 12. Eur J Immunol. 2022. PMID: 35092032 Free PMC article.
Aberrant chromatin landscape following loss of the H3.3 chaperone Daxx in haematopoietic precursors leads to Pu.1-mediated neutrophilia and inflammation.
Gerber JP, Russ J, Chandrasekar V, Offermann N, Lee HM, Spear S, Guzzi N, Maida S, Pattabiraman S, Zhang R, Kayvanjoo AH, Datta P, Kasturiarachchi J, Sposito T, Izotova N, Händler K, Adams PD, Marafioti T, Enver T, Wenzel J, Beyer M, Mass E, Bellodi C, Schultze JL, Capasso M, Nimmo R, Salomoni P. Gerber JP, et al. Nat Cell Biol. 2021 Dec;23(12):1224-1239. doi: 10.1038/s41556-021-00774-y. Epub 2021 Dec 7. Nat Cell Biol. 2021. PMID: 34876685 Free PMC article.
Increased fidelity of protein synthesis extends lifespan.
Martinez-Miguel VE, Lujan C, Espie-Caullet T, Martinez-Martinez D, Moore S, Backes C, Gonzalez S, Galimov ER, Brown AEX, Halic M, Tomita K, Rallis C, von der Haar T, Cabreiro F, Bjedov I. Martinez-Miguel VE, et al. Cell Metab. 2021 Nov 2;33(11):2288-2300.e12. doi: 10.1016/j.cmet.2021.08.017. Epub 2021 Sep 14. Cell Metab. 2021. PMID: 34525330 Free PMC article.
26 results