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Taxol: an antimitotic agent with a new mechanism of action.

Manfredi JJ, Horwitz SB. Manfredi JJ, et al. Pharmacol Ther. 1984;25(1):83-125. doi: 10.1016/0163-7258(84)90025-1. Pharmacol Ther. 1984. PMID: 6149569 Review. No abstract available.

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Taxol: mechanisms of action and resistance.

Horwitz SB, Lothstein L, Manfredi JJ, Mellado W, Parness J, Roy SN, Schiff PB, Sorbara L, Zeheb R. Horwitz SB, et al. Ann N Y Acad Sci. 1986;466:733-44. doi: 10.1111/j.1749-6632.1986.tb38455.x. Ann N Y Acad Sci. 1986. PMID: 2873780 No abstract available.

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Taxol binds to cellular microtubules.

Manfredi JJ, Parness J, Horwitz SB. Manfredi JJ, et al. J Cell Biol. 1982 Sep;94(3):688-96. doi: 10.1083/jcb.94.3.688. J Cell Biol. 1982. PMID: 6127342 Free PMC article.

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Taxol binds to polymerized tubulin in vitro.

Parness J, Horwitz SB. Parness J, et al. J Cell Biol. 1981 Nov;91(2 Pt 1):479-87. doi: 10.1083/jcb.91.2.479. J Cell Biol. 1981. PMID: 6118377 Free PMC article.

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A phosphoglycoprotein associated with taxol resistance in J774.2 cells.

Roy SN, Horwitz SB. Roy SN, et al. Cancer Res. 1985 Aug;45(8):3856-63. Cancer Res. 1985. PMID: 2861892 Free article.

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6

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Origin of malondialdehyde from DNA degraded by Fe(II) x bleomycin.

Burger RM, Berkowitz AR, Peisach J, Horwitz SB. Burger RM, et al. J Biol Chem. 1980 Dec 25;255(24):11832-8. J Biol Chem. 1980. PMID: 6160153

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VP16-213 and podophyllotoxin. A study on the relationship between chemical structure and biological activity.

Loike JD. Loike JD. Cancer Chemother Pharmacol. 1982;7(2-3):103-11. doi: 10.1007/BF00254530. Cancer Chemother Pharmacol. 1982. PMID: 7044591 Review.

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8

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Taxol: a new probe for studying the structure and function of microtubules.

Horwitz SB, Parness J, Schiff PB, Manfredi JJ. Horwitz SB, et al. Cold Spring Harb Symp Quant Biol. 1982;46 Pt 1:219-26. doi: 10.1101/sqb.1982.046.01.025. Cold Spring Harb Symp Quant Biol. 1982. PMID: 6125292 No abstract available.

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Activated bleomycin. A transient complex of drug, iron, and oxygen that degrades DNA.

Burger RM, Peisach J, Horwitz SB. Burger RM, et al. J Biol Chem. 1981 Nov 25;256(22):11636-44. J Biol Chem. 1981. PMID: 6170635 Free article.

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Redox potential of iron-bleomycin.

Melnyk DL, Horwitz SB, Peisach J. Melnyk DL, et al. Biochemistry. 1981 Sep 1;20(18):5327-31. doi: 10.1021/bi00521a036. Biochemistry. 1981. PMID: 6170321 No abstract available.

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