CA-55823/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
1995	5
1996	1
1997	1
2024	0

1

Disruption of oncogenic K-Ras4B processing and signaling by a potent geranylgeranyltransferase I inhibitor.

Lerner EC, Qian Y, Hamilton AD, Sebti SM. Lerner EC, et al. J Biol Chem. 1995 Nov 10;270(45):26770-3. doi: 10.1074/jbc.270.45.26770. J Biol Chem. 1995. PMID: 7592913 Free article.

2

Ras CAAX peptidomimetic FTI-277 selectively blocks oncogenic Ras signaling by inducing cytoplasmic accumulation of inactive Ras-Raf complexes.

Lerner EC, Qian Y, Blaskovich MA, Fossum RD, Vogt A, Sun J, Cox AD, Der CJ, Hamilton AD, Sebti SM. Lerner EC, et al. J Biol Chem. 1995 Nov 10;270(45):26802-6. doi: 10.1074/jbc.270.45.26802. J Biol Chem. 1995. PMID: 7592920 Free article.

3

CAAX peptidomimetic FTI-244 decreases platelet-derived growth factor receptor tyrosine phosphorylation levels and inhibits stimulation of phosphatidylinositol 3-kinase but not mitogen-activated protein kinase.

McGuire TF, Qian Y, Blaskovich MA, Fossum RD, Sun J, Marlowe T, Corey SJ, Wathen SP, Vogt A, Hamilton AD, et al. McGuire TF, et al. Biochem Biophys Res Commun. 1995 Sep 5;214(1):295-303. doi: 10.1006/bbrc.1995.2287. Biochem Biophys Res Commun. 1995. PMID: 7669049

4

Geranylgeraniol potentiates lovastatin inhibition of oncogenic H-Ras processing and signaling while preventing cytotoxicity.

McGuire TF, Sebti SM. McGuire TF, et al. Oncogene. 1997 Jan 23;14(3):305-12. doi: 10.1038/sj.onc.1200819. Oncogene. 1997. PMID: 9018116

5

Protein geranylgeranylation, not farnesylation, is required for the G1 to S phase transition in mouse fibroblasts.

Vogt A, Qian Y, McGuire TF, Hamilton AD, Sebti SM. Vogt A, et al. Oncogene. 1996 Nov 7;13(9):1991-9. Oncogene. 1996. PMID: 8934546

6

Ras CAAX peptidomimetic FTI 276 selectively blocks tumor growth in nude mice of a human lung carcinoma with K-Ras mutation and p53 deletion.

Sun J, Qian Y, Hamilton AD, Sebti SM. Sun J, et al. Cancer Res. 1995 Oct 1;55(19):4243-7. Cancer Res. 1995. PMID: 7671229

7

Burkitt lymphoma Daudi cells contain two distinct farnesyltransferases with different divalent cation requirements.

Vogt A, Sun J, Qian Y, Tan-Chiu E, Hamilton AD, Sebti SM. Vogt A, et al. Biochemistry. 1995 Sep 26;34(38):12398-403. doi: 10.1021/bi00038a037. Biochemistry. 1995. PMID: 7547984

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