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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
2003 1
2004 1
2007 2
2008 3
2009 5
2010 4
2011 1
2012 3
2020 1
2021 0
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20 results
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Page 1
How shelterin protects mammalian telomeres.
Palm W, de Lange T. Palm W, et al. Annu Rev Genet. 2008;42:301-34. doi: 10.1146/annurev.genet.41.110306.130350. Annu Rev Genet. 2008. PMID: 18680434 Review.
ATRX affects the repair of telomeric DSBs by promoting cohesion and a DAXX-dependent activity.
Lovejoy CA, Takai K, Huh MS, Picketts DJ, de Lange T. Lovejoy CA, et al. PLoS Biol. 2020 Jan 2;18(1):e3000594. doi: 10.1371/journal.pbio.3000594. eCollection 2020 Jan. PLoS Biol. 2020. PMID: 31895940 Free PMC article.
Removal of shelterin reveals the telomere end-protection problem.
Sfeir A, de Lange T. Sfeir A, et al. Science. 2012 May 4;336(6081):593-7. doi: 10.1126/science.1218498. Science. 2012. PMID: 22556254 Free PMC article.
Mammalian telomeres resemble fragile sites and require TRF1 for efficient replication.
Sfeir A, Kosiyatrakul ST, Hockemeyer D, MacRae SL, Karlseder J, Schildkraut CL, de Lange T. Sfeir A, et al. Cell. 2009 Jul 10;138(1):90-103. doi: 10.1016/j.cell.2009.06.021. Cell. 2009. PMID: 19596237 Free PMC article.
Loss of ATRX, genome instability, and an altered DNA damage response are hallmarks of the alternative lengthening of telomeres pathway.
Lovejoy CA, Li W, Reisenweber S, Thongthip S, Bruno J, de Lange T, De S, Petrini JH, Sung PA, Jasin M, Rosenbluh J, Zwang Y, Weir BA, Hatton C, Ivanova E, Macconaill L, Hanna M, Hahn WC, Lue NF, Reddel RR, Jiao Y, Kinzler K, Vogelstein B, Papadopoulos N, Meeker AK; ALT Starr Cancer Consortium. Lovejoy CA, et al. PLoS Genet. 2012;8(7):e1002772. doi: 10.1371/journal.pgen.1002772. Epub 2012 Jul 19. PLoS Genet. 2012. PMID: 22829774 Free PMC article.
The causes and consequences of polyploidy in normal development and cancer.
Davoli T, de Lange T. Davoli T, et al. Annu Rev Cell Dev Biol. 2011;27:585-610. doi: 10.1146/annurev-cellbio-092910-154234. Epub 2011 Jul 21. Annu Rev Cell Dev Biol. 2011. PMID: 21801013 Review.
How telomeres solve the end-protection problem.
de Lange T. de Lange T. Science. 2009 Nov 13;326(5955):948-52. doi: 10.1126/science.1170633. Science. 2009. PMID: 19965504 Free PMC article.
In vivo stoichiometry of shelterin components.
Takai KK, Hooper S, Blackwood S, Gandhi R, de Lange T. Takai KK, et al. J Biol Chem. 2010 Jan 8;285(2):1457-67. doi: 10.1074/jbc.M109.038026. Epub 2009 Oct 28. J Biol Chem. 2010. PMID: 19864690 Free PMC article.
Engineered telomere degradation models dyskeratosis congenita.
Hockemeyer D, Palm W, Wang RC, Couto SS, de Lange T. Hockemeyer D, et al. Genes Dev. 2008 Jul 1;22(13):1773-85. doi: 10.1101/gad.1679208. Epub 2008 Jun 11. Genes Dev. 2008. PMID: 18550783 Free PMC article.
How shelterin solves the telomere end-protection problem.
de Lange T. de Lange T. Cold Spring Harb Symp Quant Biol. 2010;75:167-77. doi: 10.1101/sqb.2010.75.017. Epub 2011 Jan 5. Cold Spring Harb Symp Quant Biol. 2010. PMID: 21209389
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