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Year Number of Results
2002 1
2003 1
2004 6
2005 1
2006 16
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2008 24
2009 41
2010 56
2011 50
2012 47
2013 50
2014 35
2015 32
2016 26
2017 42
2018 30
2019 30
2020 1
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Page 1
De novo design of bioactive protein switches
Langan RA, et al. Nature 2019. PMID 31341284 Free PMC article.
Allosteric regulation of protein function is widespread in biology, but is challenging for de novo protein design as it requires the explicit design of multiple states with comparable free energies. ...
Allosteric regulation of protein function is widespread in biology, but is challenging for de novo protein design as it requires the explici …
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