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An efficient strategy for evaluating new non-invasive screening tests for colorectal cancer: the guiding principles.
Bresalier RS, Senore C, Young GP, Allison J, Benamouzig R, Benton S, Bossuyt PMM, Caro L, Carvalho B, Chiu HM, Coupé VMH, de Klaver W, de Klerk CM, Dekker E, Dolwani S, Fraser CG, Grady W, Guittet L, Gupta S, Halloran SP, Haug U, Hoff G, Itzkowitz S, Kortlever T, Koulaouzidis A, Ladabaum U, Lauby-Secretan B, Leja M, Levin B, Levin TR, Macrae F, Meijer GA, Melson J, O'Morain C, Parry S, Rabeneck L, Ransohoff DF, Sáenz R, Saito H, Sanduleanu-Dascalescu S, Schoen RE, Selby K, Singh H, Steele RJC, Sung JJY, Symonds EL, Winawer SJ; Members of the World Endoscopy Colorectal Cancer Screening New Test Evaluation Expert Working Group. Bresalier RS, et al. Gut. 2023 Oct;72(10):1904-1918. doi: 10.1136/gutjnl-2023-329701. Epub 2023 Jul 18. Gut. 2023. PMID: 37463757 Free PMC article.
Reducing demographic bias in biomedical machine learning for cancer detection using cfDNA methylation.
Li S, Zeng W, Li W, Liu CC, Zhou Y, Ni X, Stackpole ML, Yeh AH, Melehy A, Lu DS, Raman SS, Hsu W, Mishra L, Shetty K, Tran B, Yokomizo M, Ahuja P, Zhu Y, Tseng HR, Aberle DR, Agopian VG, Han SB, French SW, Dubinett SM, Zhou XJ, Wong WH. Li S, et al. Genome Biol. 2026 Feb 25. doi: 10.1186/s13059-026-04006-0. Online ahead of print. Genome Biol. 2026. PMID: 41736096 Free article.
Toward the simultaneous detection of multiple diseases with a highly cost-effective cell-free DNA methylome test.
Zeng W, Liu CC, Li S, Zhou Y, Stackpole ML, Xiao Y, Hu R, Tang C, Liu Q, Zeng W, Yeh A, Melehy A, Tran B, Noor Z, Yokomizo M, Amara D, Gumate S, Ahuja P, Li DY, Zhao J, Rose I, Walker C, Malik S, Zhu Y, Tseng HR, Garon EB, French SW, Magyar CE, Dry SM, Lajonchere CM, Geschwind D, Choi G, Saab S, Shetty A, Wong CR, King KG, Lu DS, Raman SS, Xiang X, Shetty K, Mishra L, Memarzadeh S, Liu Y, Albe F, Hsu W, Krysan K, Dubinett SM, Aberle DR, Agopian V, Han SB, Wong WH, Ni X, Li W, Zhou XJ. Zeng W, et al. Proc Natl Acad Sci U S A. 2026 Apr 14;123(15):e2518347123. doi: 10.1073/pnas.2518347123. Epub 2026 Apr 6. Proc Natl Acad Sci U S A. 2026. PMID: 41941615 Free article.