CA89021/CA/NCI NIH HHS/United States[Grant Number] - Search Results

Year	Number of Results
2001	1
2002	1
2003	4
2005	5
2006	1
2007	1
2008	1
2011	1
2012	1
2013	1
2022	0

1

EZH2 oncogenic activity in castration-resistant prostate cancer cells is Polycomb-independent.

Xu K, Wu ZJ, Groner AC, He HH, Cai C, Lis RT, Wu X, Stack EC, Loda M, Liu T, Xu H, Cato L, Thornton JE, Gregory RI, Morrissey C, Vessella RL, Montironi R, Magi-Galluzzi C, Kantoff PW, Balk SP, Liu XS, Brown M. Xu K, et al. Science. 2012 Dec 14;338(6113):1465-9. doi: 10.1126/science.1227604. Science. 2012. PMID: 23239736 Free PMC article.

2

Targeting the PI3K-Akt pathway in human cancer: rationale and promise.

Luo J, Manning BD, Cantley LC. Luo J, et al. Cancer Cell. 2003 Oct;4(4):257-62. doi: 10.1016/s1535-6108(03)00248-4. Cancer Cell. 2003. PMID: 14585353 Free article. Review. No abstract available.

3

Gastrointestinal stromal tumours overexpress fatty acid synthase.

Rossi S, Ou W, Tang D, Bhattacharya N, Dei Tos AP, Fletcher JA, Loda M. Rossi S, et al. J Pathol. 2006 Jul;209(3):369-75. doi: 10.1002/path.1983. J Pathol. 2006. PMID: 16583360

4

Integrative genomic approaches identify IKBKE as a breast cancer oncogene.

Boehm JS, Zhao JJ, Yao J, Kim SY, Firestein R, Dunn IF, Sjostrom SK, Garraway LA, Weremowicz S, Richardson AL, Greulich H, Stewart CJ, Mulvey LA, Shen RR, Ambrogio L, Hirozane-Kishikawa T, Hill DE, Vidal M, Meyerson M, Grenier JK, Hinkle G, Root DE, Roberts TM, Lander ES, Polyak K, Hahn WC. Boehm JS, et al. Cell. 2007 Jun 15;129(6):1065-79. doi: 10.1016/j.cell.2007.03.052. Cell. 2007. PMID: 17574021 Free article.

5

PI3K-targeted therapy can be evaded by gene amplification along the MYC-eukaryotic translation initiation factor 4E (eIF4E) axis.

Ilic N, Utermark T, Widlund HR, Roberts TM. Ilic N, et al. Proc Natl Acad Sci U S A. 2011 Sep 13;108(37):E699-708. doi: 10.1073/pnas.1108237108. Epub 2011 Aug 29. Proc Natl Acad Sci U S A. 2011. PMID: 21876152 Free PMC article.

6

Feedback inhibition of Akt signaling limits the growth of tumors lacking Tsc2.

Manning BD, Logsdon MN, Lipovsky AI, Abbott D, Kwiatkowski DJ, Cantley LC. Manning BD, et al. Genes Dev. 2005 Aug 1;19(15):1773-8. doi: 10.1101/gad.1314605. Epub 2005 Jul 18. Genes Dev. 2005. PMID: 16027169 Free PMC article.

7

A prostatic intraepithelial neoplasia-dependent p27 Kip1 checkpoint induces senescence and inhibits cell proliferation and cancer progression.

Majumder PK, Grisanzio C, O'Connell F, Barry M, Brito JM, Xu Q, Guney I, Berger R, Herman P, Bikoff R, Fedele G, Baek WK, Wang S, Ellwood-Yen K, Wu H, Sawyers CL, Signoretti S, Hahn WC, Loda M, Sellers WR. Majumder PK, et al. Cancer Cell. 2008 Aug 12;14(2):146-55. doi: 10.1016/j.ccr.2008.06.002. Cancer Cell. 2008. PMID: 18691549 Free PMC article.

8

Breast cancer-associated PIK3CA mutations are oncogenic in mammary epithelial cells.

Isakoff SJ, Engelman JA, Irie HY, Luo J, Brachmann SM, Pearline RV, Cantley LC, Brugge JS. Isakoff SJ, et al. Cancer Res. 2005 Dec 1;65(23):10992-1000. doi: 10.1158/0008-5472.CAN-05-2612. Cancer Res. 2005. PMID: 16322248

9

Dissection of angiogenic signaling in zebrafish using a chemical genetic approach.

Chan J, Bayliss PE, Wood JM, Roberts TM. Chan J, et al. Cancer Cell. 2002 Apr;1(3):257-67. doi: 10.1016/s1535-6108(02)00042-9. Cancer Cell. 2002. PMID: 12086862 Free article.

10

Prostate intraepithelial neoplasia induced by prostate restricted Akt activation: the MPAKT model.

Majumder PK, Yeh JJ, George DJ, Febbo PG, Kum J, Xue Q, Bikoff R, Ma H, Kantoff PW, Golub TR, Loda M, Sellers WR. Majumder PK, et al. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7841-6. doi: 10.1073/pnas.1232229100. Epub 2003 Jun 10. Proc Natl Acad Sci U S A. 2003. PMID: 12799464 Free PMC article.

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