Small vessel dysfunction at 7T MRI locally predicts white matter damage progression in CADASIL.
Pham SD, van den Brink H, Kopczak A, Vlegels N, De Luca A, Gesierich B, Stringer MS, Thrippleton MJ, Wardlaw JM, Bhogal AA, Dieleman N, Zwanenburg JJ, Duering M, Biessels GJ, Siero JC.
Pham SD, et al.
J Cereb Blood Flow Metab. 2026 Feb;46(2):521-533. doi: 10.1177/0271678X251369257. Epub 2025 Aug 20.
J Cereb Blood Flow Metab. 2026.
PMID: 40832975
Free PMC article.
White matter changes were assessed on 3 T MRI over two years, analyzing mean diffusivity changes and conversion of normal-appearing white matter to white matter hyperintensities (WMH). ...However, whole-brain vascular function meas …
White matter changes were assessed on 3 T MRI over two years, analyzing mean diffusivity changes and conversion of norm …