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2015 1
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2018 1
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CCL22-specific T Cells: Modulating the immunosuppressive tumor microenvironment.
Martinenaite E, Munir Ahmad S, Hansen M, Met Ö, Westergaard MW, Larsen SK, Klausen TW, Donia M, Svane IM, Andersen MH. Martinenaite E, et al. Oncoimmunology. 2016 Sep 30;5(11):e1238541. doi: 10.1080/2162402X.2016.1238541. eCollection 2016. Oncoimmunology. 2016. PMID: 27999757 Free PMC article.
Tumor cells and tumor-infiltrating macrophages produce the chemokine CCL22, which attracts regulatory T cells (Tregs) into the tumor microenvironment, decreasing anticancer immunity. ...CCL22-specific T
Tumor cells and tumor-infiltrating macrophages produce the chemokine CCL22, which attracts regulatory T
Glycocalyx-Mimicking Nanoparticles Improve Anti-PD-L1 Cancer Immunotherapy through Reversion of Tumor-Associated Macrophages.
Zhang Y, Wu L, Li Z, Zhang W, Luo F, Chu Y, Chen G. Zhang Y, et al. Biomacromolecules. 2018 Jun 11;19(6):2098-2108. doi: 10.1021/acs.biomac.8b00305. Epub 2018 Apr 16. Biomacromolecules. 2018. PMID: 29634251
Immune checkpoint blockade by anti-PD-L1 monoclonal antibody (alphaPD-L1) has achieved unprecedented clinical benefits in certain cancers, whereas the therapeutic efficacy is often hindered by immunosuppressive tumor microenvironment mediated by tum
Immune checkpoint blockade by anti-PD-L1 monoclonal antibody (alphaPD-L1) has achieved unprecedented clinical benefits in certain can
Enhancement of adoptive T cell transfer with single low dose pretreatment of doxorubicin or paclitaxel in mice.
Hsu FT, Chen TC, Chuang HY, Chang YF, Hwang JJ. Hsu FT, et al. Oncotarget. 2015 Dec 29;6(42):44134-50. doi: 10.18632/oncotarget.6628. Oncotarget. 2015. PMID: 26683520 Free PMC article.
Currently, preconditioning with chemotherapy is used to modulate the patient immunity before ACT, however, the tumor microenvironment beneficial for transferring T cells may also be damaged. ...Enhanced therapeutic efficacy was found in Dox or T …
Currently, preconditioning with chemotherapy is used to modulate the patient immunity before ACT, however, the tumor microe