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Year Number of Results
1962 1
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1982 6
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1993 200
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1996 200
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1999 131
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2002 133
2003 155
2004 129
2005 136
2006 145
2007 122
2008 125
2009 132
2010 113
2011 106
2012 119
2013 128
2014 110
2015 99
2016 98
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4,853 results

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Page 1
PD-1(-) CD45RA(+) effector-memory CD8 T cells and CXCL10(+) macrophages are associated with response to atezolizumab plus bevacizumab in advanced hepatocellular carcinoma.
Cappuyns S, Philips G, Vandecaveye V, Boeckx B, Schepers R, Van Brussel T, Arijs I, Mechels A, Bassez A, Lodi F, Jaekers J, Topal H, Topal B, Bricard O, Qian J, Van Cutsem E, Verslype C, Lambrechts D, Dekervel J. Cappuyns S, et al. Nat Commun. 2023 Nov 29;14(1):7825. doi: 10.1038/s41467-023-43381-1. Nat Commun. 2023. PMID: 38030622 Free PMC article.
Based on T cell receptor sharing and pseudotime trajectory analysis, we propose that CD8 T(EM) preferentially differentiate into clonally-expanded PD1(- )CD45RA(+) effector-memory CD8(+) T cells (CD8 T(EMRA)) with pronounced cytotoxicity. In contrast, in non-responders, CD …
Based on T cell receptor sharing and pseudotime trajectory analysis, we propose that CD8 T(EM) preferentially differentiate into clonally-ex …
Characterization of a monoclonal antibody identifying a CD45RA antigen on feline leukocytes.
Gengozian N, Foster JS, Kestler DP. Gengozian N, et al. Vet Immunol Immunopathol. 2005 Dec 15;108(3-4):253-64. doi: 10.1016/j.vetimm.2005.05.012. Epub 2005 Jul 22. Vet Immunol Immunopathol. 2005. PMID: 16040129
Mild papain digestion of bone marrow and PBL completely removed the antigen detected by this antibody while not affecting reactivity of a pan-T antibody. Western blot analysis showed binding of the antibody to polypeptides of approximately 200 kDa on feline b …
Mild papain digestion of bone marrow and PBL completely removed the antigen detected by this antibody while not affecting reactivity …
Anti-CD45RB monoclonal antibody-mediated transplantation tolerance.
Luke PP, O'Brien CA, Jevnikar AM, Zhong R. Luke PP, et al. Curr Mol Med. 2001 Nov;1(5):533-43. doi: 10.2174/1566524013363348. Curr Mol Med. 2001. PMID: 11899229 Review.
Although predictable tolerance induction has been elusive, we found that short course of the novel immunomodulatory agent, anti-CD45RB monoclonal antibody, leads to indefinite acceptance of renal allografts in mice, and has been shown to markedly prolong allograft survival …
Although predictable tolerance induction has been elusive, we found that short course of the novel immunomodulatory agent, anti-CD45RB monoc …
Antibody-targeted therapy for myeloid leukemia.
Appelbaum FR. Appelbaum FR. Semin Hematol. 1999 Oct;36(4 Suppl 6):2-8. Semin Hematol. 1999. PMID: 10530710 Review.
The availability of antibodies reactive with antigens expressed only by hematopoietic cells has provided clinical investigators with new tools for use in developing therapies for acute myeloid leukemia (AML). ...Initial in vivo studies with an unmodified murine anti …
The availability of antibodies reactive with antigens expressed only by hematopoietic cells has provided clinical investigator …
The role of CD45RA on human B-cell function: anti-CD45RA antibody (anti-2H4) inhibits the activation of resting B cells and antibody production of activated B cells independently in humans.
Morikawa K, Oseko F, Morikawa S. Morikawa K, et al. Scand J Immunol. 1991 Sep;34(3):273-83. doi: 10.1111/j.1365-3083.1991.tb01547.x. Scand J Immunol. 1991. PMID: 1715602
Anti-CD45RA antibody defined by anti-2H4 monoclonal antibody has been reported to split CD4+T cells into two distinct subpopulations. ...In addition, anti-CD45RA antibody also had a suppressive effect on early phase of B-cell differentiation. .. …
Anti-CD45RA antibody defined by anti-2H4 monoclonal antibody has been reported to split CD4+T cells into two distinct s …
First-in-class anti-human CD45RC antibody targets CD45RC(high) T and B cells to mitigate pathogenic immune responses.
Bergua C, Ahmil-Boiteau G, Ouisse LH, Vimond N, Sérazin C, Dugast L, Humeau R, Salama A, Tesson L, Swinnen K, Van Brempt R, Collette A, Anegon I, Guillonneau C. Bergua C, et al. Mol Ther. 2026 Feb 4;34(2):1024-1046. doi: 10.1016/j.ymthe.2025.10.057. Epub 2025 Oct 30. Mol Ther. 2026. PMID: 41174880 Free article.
CD45RC, an isoform of the transmembrane tyrosine phosphatase CD45, regulates T and B cell antigen receptor signaling and is highly expressed on Th1 precursors, Th1 cells, T effector memory CD45RA(+) cells, and most B cells. Preclinical studies have shown that anti-CD45RC m …
CD45RC, an isoform of the transmembrane tyrosine phosphatase CD45, regulates T and B cell antigen receptor signaling and is highly expressed …
CD45RA T-cell activation without proliferation by a partial agonist monoclonal antibody to beta1 integrin.
Billard MJ, McIntyre BW. Billard MJ, et al. Immunol Cell Biol. 2008 May-Jun;86(4):381-4. doi: 10.1038/sj.icb.7100165. Epub 2008 Jan 15. Immunol Cell Biol. 2008. PMID: 18195724
CD45RA T cells are fully co-activated by natural beta1 integrin ligands fibronectin (FN) and VCAM-1, as well as monoclonal antibody (mAb) 19H8, which binds a combinatorial epitope of the alpha4beta1 heterodimer. These integrin ligands stimulate CD3-dependent prolife …
CD45RA T cells are fully co-activated by natural beta1 integrin ligands fibronectin (FN) and VCAM-1, as well as monoclonal antibod …
Sensitive antibody-based CTCs detection from peripheral blood.
Shahneh FZ. Shahneh FZ. Hum Antibodies. 2013;22(1-2):51-4. doi: 10.3233/HAB-130270. Hum Antibodies. 2013. PMID: 24284308 Review.
Different characteristics of tumor cells have been applied to define enrichment methods through the differential expression of tumor-specific markers on the surface of the cells. Antibody-based affinity methods can provide the separation of CTCs via the expression of speci …
Different characteristics of tumor cells have been applied to define enrichment methods through the differential expression of tumor-specifi …
Monoclonal antibody against CD45RB for the therapy of rejection and autoimmune diseases.
Zhong RZ, Lazarovits AI. Zhong RZ, et al. J Mol Med (Berl). 1998 Jul;76(8):572-80. doi: 10.1007/s001090050252. J Mol Med (Berl). 1998. PMID: 9694434 Review.
We have recently reported that a monoclonal antibody against CD45RB is a potent immunosuppressive agent, and that it induces donor specific tolerance in the mouse. ...
We have recently reported that a monoclonal antibody against CD45RB is a potent immunosuppressive agent, and that it induces donor sp …
Development of an anti-CD45RA-quantum dots conjugated scFv to detect leukemic cancer stem cells.
Moradi-Kalbolandi S, Dashtestani F, Salehi M, Jalili N, Majidzadeh-A K, Rahighi R, Yadegari A, Farahmand L. Moradi-Kalbolandi S, et al. Mol Biol Rep. 2020 Jan;47(1):225-234. doi: 10.1007/s11033-019-05122-w. Epub 2019 Oct 22. Mol Biol Rep. 2020. PMID: 31642038
The variable light and heavy chain sequences of a recently developed anti-CD45RA monoclonal antibody were derived from hybridoma cells and PCR amplified to construct scFv. ...Based on results, purified CD45RA scFv conjugated C dots could specifically recogniz …
The variable light and heavy chain sequences of a recently developed anti-CD45RA monoclonal antibody were derived from hybrido …
4,853 results