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CD95 maintains stem cell-like and non-classical EMT programs in primary human glioblastoma cells.
Drachsler M, Kleber S, Mateos A, Volk K, Mohr N, Chen S, Cirovic B, Tüttenberg J, Gieffers C, Sykora J, Wirtz CR, Mueller W, Synowitz M, Martin-Villalba A. Drachsler M, et al. Cell Death Dis. 2016 Apr 28;7(4):e2209. doi: 10.1038/cddis.2016.102. Cell Death Dis. 2016. PMID: 27124583 Free PMC article.
In this study, we show that the expression of CD95 associates with stemness and EMT features in GBM tumors and cells and serves as a prognostic biomarker. ...Recruitment of the activating PI3K subunit, p85, to CD95 death domain is required for maint
In this study, we show that the expression of CD95 associates with stemness and EMT features in GBM tumors and cells an …