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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1997 3
1998 2
2001 3
2002 5
2003 9
2004 10
2005 8
2006 16
2007 10
2008 11
2009 14
2010 9
2011 14
2012 12
2013 22
2014 19
2015 18
2016 19
2017 11
2018 17
2019 13
2020 10
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218 results
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Page 1
Different pathways of macrophage activation and polarization.
Juhas U, Ryba-Stanisławowska M, Szargiej P, Myśliwska J. Juhas U, et al. Postepy Hig Med Dosw (Online). 2015 Apr 22;69:496-502. doi: 10.5604/17322693.1150133. Postepy Hig Med Dosw (Online). 2015. PMID: 25983288 Free article. Review.
When monocytes are recruited to an area of infection they may differentiate into macrophages. In different microenvironments macrophages polarize into two types. ...Mediators of M1 macrophage TLR-dependent polarization include transcription factors such as NF …
When monocytes are recruited to an area of infection they may differentiate into macrophages. In different microenvironments macro …
An autonomous CEBPA enhancer specific for myeloid-lineage priming and neutrophilic differentiation.
Avellino R, Havermans M, Erpelinck C, Sanders MA, Hoogenboezem R, van de Werken HJ, Rombouts E, van Lom K, van Strien PM, Gebhard C, Rehli M, Pimanda J, Beck D, Erkeland S, Kuiken T, de Looper H, Gröschel S, Touw I, Bindels E, Delwel R. Avellino R, et al. Blood. 2016 Jun 16;127(24):2991-3003. doi: 10.1182/blood-2016-01-695759. Epub 2016 Mar 10. Blood. 2016. PMID: 26966090 Free PMC article.
Neutrophilic differentiation is dependent on CCAAT enhancer-binding protein α (C/EBPα), a transcription factor expressed in multiple organs including the bone marrow. ...We conclude that a single +42-kb enhancer is essential for CEBPA exp …
Neutrophilic differentiation is dependent on CCAAT enhancer-binding protein α (C/EBPα), a transcription factor e …
Labelled regulatory elements are pervasive features of the macrophage genome and are dynamically utilized by classical and alternative polarization signals.
Horvath A, Daniel B, Szeles L, Cuaranta-Monroy I, Czimmerer Z, Ozgyin L, Steiner L, Kiss M, Simandi Z, Poliska S, Giannakis N, Raineri E, Gut IG, Nagy B, Nagy L. Horvath A, et al. Nucleic Acids Res. 2019 Apr 8;47(6):2778-2792. doi: 10.1093/nar/gkz118. Nucleic Acids Res. 2019. PMID: 30799488 Free PMC article.
However, the guiding principles of LDTF binding, chromatin accessibility and enhancer activity have not yet been systematically evaluated. ...We show that Random Forest and Support Vector Regression machine learning methods can accurately predict chromatin accessibi …
However, the guiding principles of LDTF binding, chromatin accessibility and enhancer activity have not yet been systematicall …
CCAAT/enhancer-binding protein alpha (CEBPA) gene haploinsufficiency does not alter hematopoiesis or induce leukemia in Lck-CALM/AF10 transgenic mice.
Lange AP, Almeida LY, Araújo Silva CL, Scheucher PS, Chahud F, Krause A, Bohlander SK, Rego EM. Lange AP, et al. Braz J Med Biol Res. 2019;52(6):e8424. doi: 10.1590/1414-431X20198424. Epub 2019 May 27. Braz J Med Biol Res. 2019. PMID: 31141090 Free PMC article.
Moreover, this translocation is detected in 50% of T-ALL patients with gamma/delta T cell receptor rearrangement, frequently associated with low expression of transcription factor CCAAT/enhancer-binding protein alpha (CEBPA). ...To charac …
Moreover, this translocation is detected in 50% of T-ALL patients with gamma/delta T cell receptor rearrangement, frequently associated with …
Subtype-specific patterns of molecular mutations in acute myeloid leukemia.
Rose D, Haferlach T, Schnittger S, Perglerová K, Kern W, Haferlach C. Rose D, et al. Leukemia. 2017 Jan;31(1):11-17. doi: 10.1038/leu.2016.163. Epub 2016 Jun 10. Leukemia. 2017. PMID: 27285584
We investigated mutations in 20 genes, including myeloid transcription factors (CEBPA, RUNX1), tumor suppressors (TP53, WT1), DNA modifiers (DNMT3A, IDH1/2, TET2), chromatin modifiers (ASXL1, MLL), signal transduction genes (FLT3, KRAS, NRAS) and NPM1. ...FLT3, NPM1 and WT …
We investigated mutations in 20 genes, including myeloid transcription factors (CEBPA, RUNX1), tumor suppressors (TP53, WT1), DNA mod …
Different Achilles Tendon Pathologies Show Distinct Histological and Molecular Characteristics.
Klatte-Schulz F, Minkwitz S, Schmock A, Bormann N, Kurtoglu A, Tsitsilonis S, Manegold S, Wildemann B. Klatte-Schulz F, et al. Int J Mol Sci. 2018 Jan 30;19(2):404. doi: 10.3390/ijms19020404. Int J Mol Sci. 2018. PMID: 29385715 Free PMC article. Clinical Trial.
In all three tendon pathology groups markers of inflammation (interleukin (IL) 1β, tumor necrosis factor α, IL6, IL10, IL33, soluble ST2, transforming growth factor β1, cyclooxygenase 2), inflammatory cells (cluster of differentaition (CD) 3, CD68, CD80, CD206), fat metabolism (f …
In all three tendon pathology groups markers of inflammation (interleukin (IL) 1β, tumor necrosis factor α, IL6, IL10, IL33, soluble ST2, tr …
Vitamin D Signaling in the Context of Innate Immunity: Focus on Human Monocytes.
Carlberg C. Carlberg C. Front Immunol. 2019 Sep 13;10:2211. doi: 10.3389/fimmu.2019.02211. eCollection 2019. Front Immunol. 2019. PMID: 31572402 Free PMC article. Review.
Monocytes and their differentiated phenotypes, macrophages and dendritic cells, are key cell types of the innate immune system, in which vitamin D signaling was most comprehensively investigated via the use of next generation sequencing technologies. These investigations p …
Monocytes and their differentiated phenotypes, macrophages and dendritic cells, are key cell types of the innate immune system, in wh …
Omega-3 Fatty Acids Activate Ciliary FFAR4 to Control Adipogenesis.
Hilgendorf KI, Johnson CT, Mezger A, Rice SL, Norris AM, Demeter J, Greenleaf WJ, Reiter JF, Kopinke D, Jackson PK. Hilgendorf KI, et al. Cell. 2019 Nov 27;179(6):1289-1305.e21. doi: 10.1016/j.cell.2019.11.005. Epub 2019 Nov 21. Cell. 2019. PMID: 31761534
The regulatory control of Cebpa enhancers and silencers in the myeloid and red-blood cell lineages.
Repele A, Krueger S, Bhattacharyya T, Tuineau MY, Manu. Repele A, et al. PLoS One. 2019 Jun 10;14(6):e0217580. doi: 10.1371/journal.pone.0217580. eCollection 2019. PLoS One. 2019. PMID: 31181110 Free PMC article.
Cebpa encodes a transcription factor (TF) that plays an instructive role in the development of multiple myeloid lineages. The expression of Cebpa itself is finely modulated, as Cebpa is expressed at high and intermediate levels in neutrophils and macrophag …
Cebpa encodes a transcription factor (TF) that plays an instructive role in the development of multiple myeloid lineages. The express …
Tet2 Regulates Osteoclast Differentiation by Interacting with Runx1 and Maintaining Genomic 5-Hydroxymethylcytosine (5hmC).
Chu Y, Zhao Z, Sant DW, Zhu G, Greenblatt SM, Liu L, Wang J, Cao Z, Tho JC, Chen S, Liu X, Zhang P, Maciejewski JP, Nimer S, Wang G, Yuan W, Yang FC, Xu M. Chu Y, et al. Genomics Proteomics Bioinformatics. 2018 Jun;16(3):172-186. doi: 10.1016/j.gpb.2018.04.005. Epub 2018 Jun 13. Genomics Proteomics Bioinformatics. 2018. PMID: 29908294 Free PMC article.
Deletion of Tet2 impairs the differentiation of osteoclast precursor cells (macrophages) and their maturation into bone-resorbing osteoclasts in vitro. ...Tet2 loss in macrophages results in the altered expression of a set of genes implicated in osteoclast different …
Deletion of Tet2 impairs the differentiation of osteoclast precursor cells (macrophages) and their maturation into bone-resorbing ost …
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