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11,755 results

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Page 1
Calcitonin gene-related peptide (CGRP): role in migraine pathophysiology and therapeutic targeting.
Wattiez AS, Sowers LP, Russo AF. Wattiez AS, et al. Expert Opin Ther Targets. 2020 Feb;24(2):91-100. doi: 10.1080/14728222.2020.1724285. Epub 2020 Feb 13. Expert Opin Ther Targets. 2020. PMID: 32003253 Free PMC article. Review.
Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a critical player in migraine pathophysiology. ...We speculate that this may reflect the redundancy of peptides within the CGRP family and a second …
Introduction: The neuropeptide calcitonin gene-related peptide (CGRP) is recognized as a critical player …
Calcitonin gene-related peptide: physiology and pathophysiology.
Russell FA, King R, Smillie SJ, Kodji X, Brain SD. Russell FA, et al. Physiol Rev. 2014 Oct;94(4):1099-142. doi: 10.1152/physrev.00034.2013. Physiol Rev. 2014. PMID: 25287861 Free PMC article. Review.
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30 years ago, it is produced as a consequence of alternative RNA processing of the calcitonin gene. ...Other areas covered, where there is less info …
Calcitonin gene-related peptide (CGRP) is a 37-amino acid neuropeptide. Discovered 30 years ago, it is pr …
Calcitonin gene-related peptide (CGRP) monoclonal antibodies for migraine.
Giffin NJ. Giffin NJ. Pract Neurol. 2023 Jun;23(3):200-207. doi: 10.1136/pn-2022-003592. Epub 2023 Feb 8. Pract Neurol. 2023. PMID: 36754606 Review.
The introduction of calcitonin gene-related peptide monoclonal antibodies represents a step forward in preventive migraine treatment as the first agents to target the underlying pathogenesis of migraine. ...
The introduction of calcitonin gene-related peptide monoclonal antibodies represents a step forward in preventiv …
Calcitonin Gene-Related Peptide (CGRP) Antagonists and Their Use in Migraines.
Henson B, Hollingsworth H, Nevois E, Herndon C. Henson B, et al. J Pain Palliat Care Pharmacother. 2020 Mar;34(1):22-31. doi: 10.1080/15360288.2019.1690616. Epub 2019 Nov 25. J Pain Palliat Care Pharmacother. 2020. PMID: 31763951 Review.
Current preventive medications have variable efficacy and their use is often limited by intolerable side effects. Calcitonin gene-related peptide (CGRP) has been identified as an integral part of migraine pathophysiology. ...The purpose of this …
Current preventive medications have variable efficacy and their use is often limited by intolerable side effects. Calcitonin gene …
Calcitonin gene-related peptide (CGRP): A novel target for Alzheimer's disease.
Singh Y, Gupta G, Shrivastava B, Dahiya R, Tiwari J, Ashwathanarayana M, Sharma RK, Agrawal M, Mishra A, Dua K. Singh Y, et al. CNS Neurosci Ther. 2017 Jun;23(6):457-461. doi: 10.1111/cns.12696. Epub 2017 Apr 17. CNS Neurosci Ther. 2017. PMID: 28417590 Free PMC article. Review.
Cholinergic treatment could be the best suitable physiological therapy for AD. Calcitonin gene-related peptide (CGRP) is a thirty-seven-amino acid regulatory neuropeptide resulting from different merging of the CGRP gene, which als …
Cholinergic treatment could be the best suitable physiological therapy for AD. Calcitonin gene-related peptide ( …
Novel Calcitonin Gene-Related Peptide (CGRP) Interfering Migraine Therapies and Stroke-A Review.
Eller MT, Frank F, Kaltseis K, Karisik A, Knoflach M, Broessner G. Eller MT, et al. Int J Mol Sci. 2024 Oct 30;25(21):11685. doi: 10.3390/ijms252111685. Int J Mol Sci. 2024. PMID: 39519240 Free PMC article. Review.
Recent advances in migraine therapy have focused on the calcitonin gene-related peptide (CGRP) pathway. This review examines the shared pathomechanisms between migraine and stroke, with emphasis on the role of CGRP. ...Concerns have been …
Recent advances in migraine therapy have focused on the calcitonin gene-related peptide (CGRP) pathway. T …
Calcitonin Gene-Related Peptide (CGRP)-Targeted Monoclonal Antibodies and Antagonists in Migraine: Current Evidence and Rationale.
Cohen F, Yuan H, Silberstein SD. Cohen F, et al. BioDrugs. 2022 May;36(3):341-358. doi: 10.1007/s40259-022-00530-0. Epub 2022 Apr 27. BioDrugs. 2022. PMID: 35476215 Free PMC article. Review.
Calcitonin gene-related peptide (CGRP), a 37 amino-acid neuropeptide found mostly in peptidergic sensory C-fibers, has been suggested to be implicated in the pathogenesis of migraine, which is one of the most common neurological disorders seen i …
Calcitonin gene-related peptide (CGRP), a 37 amino-acid neuropeptide found mostly in peptidergic sensory …
Is calcitonin gene-related peptide (CGRP) the missing link in food histamine-induced migraine? A review of functional gut-to-trigeminovascular system connections.
de Mora F, Messlinger K. de Mora F, et al. Drug Discov Today. 2024 Apr;29(4):103941. doi: 10.1016/j.drudis.2024.103941. Epub 2024 Mar 5. Drug Discov Today. 2024. PMID: 38447930 Free article. Review.
Calcitonin gene-related peptide (CGRP) and histamine plasma concentrations increase during migraine attacks. ...A high-histamine-content diet triggers migraine in patients who have histamine degradation deficiency owing to diaminooxidase (DAO) …
Calcitonin gene-related peptide (CGRP) and histamine plasma concentrations increase during migraine attac …
Calcitonin gene-related peptide (CGRP)-targeted therapies as preventive and acute treatments for migraine-The monoclonal antibodies and gepants.
Chiang CC, Schwedt TJ. Chiang CC, et al. Prog Brain Res. 2020;255:143-170. doi: 10.1016/bs.pbr.2020.06.019. Epub 2020 Jul 22. Prog Brain Res. 2020. PMID: 33008505 Review.
Calcitonin Gene-Related Peptide (CGRP) plays a pivotal role in migraine pathophysiology. Two types of CGRP function-blocking modalities, monoclonal antibodies, and small molecules (gepants), have been developed to target the CGRP l …
Calcitonin Gene-Related Peptide (CGRP) plays a pivotal role in migraine pathophysiology. Two types of …
Evolution of calcitonin/calcitonin gene-related peptide family in chordates: Identification of CT/CGRP family peptides in cartilaginous fish genome.
Sekiguchi T. Sekiguchi T. Gen Comp Endocrinol. 2022 Nov 1;328:114123. doi: 10.1016/j.ygcen.2022.114123. Epub 2022 Sep 6. Gen Comp Endocrinol. 2022. PMID: 36075341 Review.
The calcitonin (CT)/CT gene-related peptide (CGRP) family is a peptide gene family that is widely found in bilaterians. CT, CGRP, adrenomedullin (AM), amylin (AMY), and CT receptor-stimulating peptide (CRSP) are membe …
The calcitonin (CT)/CT gene-related peptide (CGRP) family is a peptide gene family that is …
11,755 results
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