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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2003 1
2004 3
2005 1
2006 5
2007 1
2008 1
2009 2
2010 4
2011 2
2013 1
2014 4
2015 2
2016 1
2026 0

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23 results

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Page 1
Hypermethylation of Chfr and hMLH1 in gastric noninvasive and early invasive neoplasias.
Homma N, Tamura G, Honda T, Jin Z, Ohmura K, Kawata S, Motoyama T. Homma N, et al. Virchows Arch. 2005 Feb;446(2):120-6. doi: 10.1007/s00428-004-1146-6. Epub 2004 Dec 10. Virchows Arch. 2005. PMID: 15735977
Hypermethylation was less frequent in L-NIN than H-NIN (P<0.05) for Chfr and was also less frequent in L-NIN than the others (P<0.05) for hMLH1. We failed to find a significant correlation between Chfr hypermethylation and chromosomal loss of heterozygosity, a …
Hypermethylation was less frequent in L-NIN than H-NIN (P<0.05) for Chfr and was also less frequent in L-NIN than the others (P&lt …
Predictive value of CHFR and MLH1 methylation in human gastric cancer.
Li Y, Yang Y, Lu Y, Herman JG, Brock MV, Zhao P, Guo M. Li Y, et al. Gastric Cancer. 2015 Apr;18(2):280-7. doi: 10.1007/s10120-014-0370-2. Epub 2014 Apr 21. Gastric Cancer. 2015. PMID: 24748501 Free PMC article.
No association was found between methylation of CHFR, MLH1, RASSF1A, MGMT, or FANCF with gender, age, tumor size, tumor differentiation, lymph node metastasis, and TNM stage. In docetaxel-treated gastric cancer patients, resistance to docetaxel was found in CHFR unm …
No association was found between methylation of CHFR, MLH1, RASSF1A, MGMT, or FANCF with gender, age, tumor size, tumor differentiati …
Pathobiologic implications of methylation and expression status of Runx3 and CHFR genes in gastric cancer.
Hu SL, Huang DB, Sun YB, Wu L, Xu WP, Yin S, Chen J, Jiang XD, Shen G. Hu SL, et al. Med Oncol. 2011 Jun;28(2):447-54. doi: 10.1007/s12032-010-9467-6. Epub 2010 Mar 19. Med Oncol. 2011. PMID: 20300977
Runx3 and CHFR genes were defined as tumor suppressor genes in gastric cancer (GC) recently. This paper was to investigate the roles of methylation and expression status of Runx3 and CHFR genes in GC patients. ...The expression of the protein and mRNA decreased rema …
Runx3 and CHFR genes were defined as tumor suppressor genes in gastric cancer (GC) recently. This paper was to investigate the roles …
Mechanism and pathobiologic implications of CHFR promoter methylation in gastric carcinoma.
Gao YJ, Xin Y, Zhang JJ, Zhou J. Gao YJ, et al. World J Gastroenterol. 2008 Aug 28;14(32):5000-7. doi: 10.3748/wjg.14.5000. World J Gastroenterol. 2008. PMID: 18763281 Free PMC article.
AIM: To investigate the aberrant methylation of CHFR promoter in human gastric cancer (GC) and its impact on the expression of CHFR mRNA and protein, as well as its correlation with clinical and histological features of human GC. ...The CHFR protein expressio …
AIM: To investigate the aberrant methylation of CHFR promoter in human gastric cancer (GC) and its impact on the expression of CHF …
Gene methylation in gastric cancer.
Qu Y, Dang S, Hou P. Qu Y, et al. Clin Chim Acta. 2013 Sep 23;424:53-65. doi: 10.1016/j.cca.2013.05.002. Epub 2013 May 10. Clin Chim Acta. 2013. PMID: 23669186 Free article. Review.
Promoter hypermethylation and silencing of CHFR mitotic stress checkpoint gene in human gastric cancers.
Kang HC, Kim IJ, Park JH, Shin Y, Park HW, Ku JL, Yang HK, Lee KU, Choe KJ, Park JG. Kang HC, et al. Oncol Rep. 2004 Jul;12(1):129-33. Oncol Rep. 2004. PMID: 15201973
CHFR is a recently identified mitotic stress check-point gene. CHFR is ubiquitously expressed in normal human tissues, whereas loss of CHFR expression has been observed in human tumors. ...A series of primary gastric tumors were also analyzed for CHFR …
CHFR is a recently identified mitotic stress check-point gene. CHFR is ubiquitously expressed in normal human tissues, whereas …
Promoter methylation of CHFR gene in gastric carcinoma tissues detected using two methods.
Cheng ZD, Hu SL, Sun YB, Xu WP, Shen G, Kong XY. Cheng ZD, et al. Chin J Cancer. 2010 Feb;29(2):163-6. doi: 10.5732/cjc.009.10305. Chin J Cancer. 2010. PMID: 20109344 Free article.
CONCLUSIONS: Aberrant methylation of the CHFR gene is a frequent event in the carcinogenesis of gastric cancer. Detecting the methylation of CHFR gene in gastric mucosa may conduce to the diagnosis of gastric cancer. No difference was found between MSP and COBRA in …
CONCLUSIONS: Aberrant methylation of the CHFR gene is a frequent event in the carcinogenesis of gastric cancer. Detecting the methyla …
Promoter methylation of p16, Runx3, DAPK and CHFR genes is frequent in gastric carcinoma.
Hu SL, Kong XY, Cheng ZD, Sun YB, Shen G, Xu WP, Wu L, Xu XC, Jiang XD, Huang DB. Hu SL, et al. Tumori. 2010 Sep-Oct;96(5):726-33. doi: 10.1177/030089161009600515. Tumori. 2010. PMID: 21302620
In addition, the mRNA expression of p16, Runx3, DAPK and CHFR was investigated in 34 gastric cancer patients by RT-PCR. Bisulfite DNA sequence analysis was applied to check the positive samples detected by MSP. ...CONCLUSIONS: Promoter hypermethylation of p16, Runx3, DAPK …
In addition, the mRNA expression of p16, Runx3, DAPK and CHFR was investigated in 34 gastric cancer patients by RT-PCR. Bisulfite DNA …
Epigenetic inactivation of CHFR and sensitivity to microtubule inhibitors in gastric cancer.
Satoh A, Toyota M, Itoh F, Sasaki Y, Suzuki H, Ogi K, Kikuchi T, Mita H, Yamashita T, Kojima T, Kusano M, Fujita M, Hosokawa M, Endo T, Tokino T, Imai K. Satoh A, et al. Cancer Res. 2003 Dec 15;63(24):8606-13. Cancer Res. 2003. PMID: 14695171
Apparently, the absence of CHFR is associated with sensitivity of cells to mitotic stress caused by microtubule inhibition, and restoration of CHFR expression by 5-aza-2'-deoxycytidine or adenoviral gene transfer restored the checkpoint. By affecting mitotic checkpo …
Apparently, the absence of CHFR is associated with sensitivity of cells to mitotic stress caused by microtubule inhibition, and resto …
Aberrant methylation of the CHFR gene in digestive tract cancer.
Morioka Y, Hibi K, Sakai M, Koike M, Fujiwara M, Kodera Y, Ito K, Nakao A. Morioka Y, et al. Anticancer Res. 2006 May-Jun;26(3A):1791-5. Anticancer Res. 2006. PMID: 16827108 Free article.
BACKGROUND: Recently, aberrant methylation of the CHFR gene associated with gene silencing has been reported in several cancers. The methylation status of the CHFR gene was examined in primary esophageal and gastric carcinomas. MATERIALS AND METHODS: The methylation …
BACKGROUND: Recently, aberrant methylation of the CHFR gene associated with gene silencing has been reported in several cancers. The …
23 results