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2013 1
2026 7

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Page 1
Therapeutic Peptides in Orthopaedics: Applications, Challenges, and Future Directions.
Rahman OF, Lee SJ, Seeds WA. Rahman OF, et al. J Am Acad Orthop Surg Glob Res Rev. 2026 Jan 2;10(1):e25.00236. doi: 10.5435/JAAOSGlobal-D-25-00236. eCollection 2026 Jan 1. J Am Acad Orthop Surg Glob Res Rev. 2026. PMID: 41490200 Free PMC article. Review.
Wound-healing peptides such as BPC-157, TB-500, and GHK-Cu promote angiogenesis, integrin-mediated extracellular matrix remodeling, and fibroblast activation, whereas growth hormone secretagogues like ipamorelin, CJC-1295, tesamorelin, sermorelin, and AOD-960 …
Wound-healing peptides such as BPC-157, TB-500, and GHK-Cu promote angiogenesis, integrin-mediated extracellular matrix remodeling, and fibr …
Injectable Peptide Therapy: A Primer for Orthopaedic and Sports Medicine Physicians.
Mayfield CK, Bolia IK, Feingold CL, Lin EH, Liu JN, Rick Hatch GF, Gamradt SC, Weber AE. Mayfield CK, et al. Am J Sports Med. 2026 Jan;54(1):223-229. doi: 10.1177/03635465251357593. Epub 2026 Jan 1. Am J Sports Med. 2026. PMID: 41476424 Review.
Key peptides evaluated included BPC-157, TB-4, TB-500, CJC-1295 + ipamorelin, tesamorelin, and GHK-Cu. RESULTS: BPC-157 demonstrated potential benefits in tendon and muscle repair, but these findings are largely unvalidated in human trials. ...TB-4 and its de …
Key peptides evaluated included BPC-157, TB-4, TB-500, CJC-1295 + ipamorelin, tesamorelin, and GHK-Cu. RESULTS: BPC-157 …
Therapeutic peptides in gerontology: mechanisms and applications for healthy aging.
Mavrych V, Shypilova I, Bolgova O. Mavrych V, et al. Front Aging. 2026 Apr 7;7:1790247. doi: 10.3389/fragi.2026.1790247. eCollection 2026. Front Aging. 2026. PMID: 42021992 Free PMC article. Review.
Search terms included "peptide therapeutics," "aging," "gerontology," "healthspan," combined with specific peptide names (tirzepatide, epitalon, GHK-Cu, BPC-157, TB-500, Semax, CJC-1295, ipamorelin, bremelanotide). Peer-reviewed articles, clinical trials, reg …
Search terms included "peptide therapeutics," "aging," "gerontology," "healthspan," combined with specific peptide names (tirzepatide, epita …
A new era of doping? Use of peptide and peptide-analog drugs in recreational and professional sport and bodybuilding: a critical review.
Coutinho LFD, DE Oliveira Neves LF, Camilo RP. Coutinho LFD, et al. J Sports Med Phys Fitness. 2026 Mar 25. doi: 10.23736/S0022-4707.26.17773-1. Online ahead of print. J Sports Med Phys Fitness. 2026. PMID: 41880199
Marketed as more selective and ostensibly safer alternatives, peptides-including growth hormone secretagogues (e.g., Ipamorelin), growth hormone-releasing hormone analogues (e.g., CJC-1295, Sermorelin), and synthetic fragments (e.g., Frag 176-191, KPV)-are pr …
Marketed as more selective and ostensibly safer alternatives, peptides-including growth hormone secretagogues (e.g., Ipamorelin), gro …
Injectable Peptides in Sports Medicine: A Structured Narrative Review of Evidence, Safety, and Antidoping Implications.
Villegas Meza AD, Nocek M, Mitchell BC, Lizarraga M, DeFoor MT, Ruzbarsky JJ, Huard J, Philippon MJ. Villegas Meza AD, et al. JBJS Rev. 2026 May 20;14(5). doi: 10.2106/JBJS.RVW.26.00027. eCollection 2026 May 1. JBJS Rev. 2026. PMID: 42160466 Review.
Regenerative peptides (e.g., body protection compound-157 and thymosin derivatives) and growth hormone axis secretagogues (e.g., CJC-1295, ipamorelin, and tesamorelin) remain investigational, with uncertain safety profiles, product quality concerns, and wides …
Regenerative peptides (e.g., body protection compound-157 and thymosin derivatives) and growth hormone axis secretagogues (e.g., CJC- …
Doping control analysis of seven bioactive peptides in horse plasma by liquid chromatography-mass spectrometry.
Kwok WH, Ho EN, Lau MY, Leung GN, Wong AS, Wan TS. Kwok WH, et al. Anal Bioanal Chem. 2013 Mar;405(8):2595-606. doi: 10.1007/s00216-012-6697-9. Epub 2013 Jan 15. Anal Bioanal Chem. 2013. PMID: 23318763
In our study, a simple mixed-mode anion exchange solid-phase extraction cartridge was employed for the extraction of seven target peptides (GHRP-1, GHRP-2, GHRP-6, ipamorelin, hexarelin, CJC-1295, and N-acetylated LKKTETQ (active ingredient of TB-500)) and th …
In our study, a simple mixed-mode anion exchange solid-phase extraction cartridge was employed for the extraction of seven target peptides ( …
Safety and Efficacy of Approved and Unapproved Peptide Therapies for Musculoskeletal Injuries and Athletic Performance.
Mendias CL, Awan TM. Mendias CL, et al. Sports Med. 2026 Apr 12. doi: 10.1007/s40279-026-02437-0. Online ahead of print. Sports Med. 2026. PMID: 41966639 Review.
Our objective is to present the pharmacological mechanisms, safety profiles, and regulatory status of prominent approved and unapproved peptides marketed direct to patients, including AOD-9604 (anti-obesity drug 9604), BPC-157 (body protection compound 157), CJC-1295 …
Our objective is to present the pharmacological mechanisms, safety profiles, and regulatory status of prominent approved and unapproved pept …