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Estimating glomerular filtration rate from serum creatinine and cystatin C.
Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, Kusek JW, Manzi J, Van Lente F, Zhang YL, Coresh J, Levey AS; CKD-EPI Investigators. Inker LA, et al. N Engl J Med. 2012 Jul 5;367(1):20-9. doi: 10.1056/NEJMoa1114248. N Engl J Med. 2012. PMID: 22762315 Free PMC article.
In the validation data set, the creatinine-cystatin C equation performed better than equations that used creatinine or cystatin C alone. ...CONCLUSIONS: The combined creatinine-cystatin C equation performed bet …
In the validation data set, the creatinine-cystatin C equation performed better than equations that used creatin …
A Unifying Approach for GFR Estimation: Recommendations of the NKF-ASN Task Force on Reassessing the Inclusion of Race in Diagnosing Kidney Disease.
Delgado C, Baweja M, Crews DC, Eneanya ND, Gadegbeku CA, Inker LA, Mendu ML, Miller WG, Moxey-Mims MM, Roberts GV, St Peter WL, Warfield C, Powe NR. Delgado C, et al. Am J Kidney Dis. 2022 Feb;79(2):268-288.e1. doi: 10.1053/j.ajkd.2021.08.003. Epub 2021 Sep 23. Am J Kidney Dis. 2022. PMID: 34563581 Review.
RECOMMENDATIONS: (1) For US adults (>85% of whom have normal kidney function), we recommend immediate implementation of the CKD-EPI creatinine equation refit without the race variable in all laboratories in the United States because it does not include rac …
RECOMMENDATIONS: (1) For US adults (>85% of whom have normal kidney function), we recommend immediate implementation of the CKD- …
Combined creatinine-cystatin C CKD-EPI equation significantly underestimates measured glomerular filtration rate in people with type 2 diabetes mellitus.
Machado JD, Camargo EG, Boff R, da Silva Rodrigues L, Camargo JL, Soares AA, Silveiro SP. Machado JD, et al. Clin Biochem. 2018 Mar;53:43-48. doi: 10.1016/j.clinbiochem.2018.01.005. Epub 2018 Jan 10. Clin Biochem. 2018. PMID: 29331592 Clinical Trial.
GFR was measured by (51)Cr-EDTA and estimated (eGFR) by the following equations using creatinine, cysC or both markers: Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI), Caucasian Asian Pediatrics and Adults (CAPA), CKD-EPI creatinine …
GFR was measured by (51)Cr-EDTA and estimated (eGFR) by the following equations using creatinine, cysC or both markers: Chronic Kidne …
CKD-EPI creatinine-cystatin C glomerular filtration rate estimation equation seems more suitable for Chinese patients with chronic kidney disease than other equations.
Chi XH, Li GP, Wang QS, Qi YS, Huang K, Zhang Q, Xue YM. Chi XH, et al. BMC Nephrol. 2017 Jul 10;18(1):226. doi: 10.1186/s12882-017-0637-z. BMC Nephrol. 2017. PMID: 28693441 Free PMC article.
The estimated GFRs (eGFRs) calculated separately by three Diet in Renal Disease (MDRD) equations and three Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equations were compared with the reference GFR (rGFR) measured by the (99)Tc(m)-DTPA …
The estimated GFRs (eGFRs) calculated separately by three Diet in Renal Disease (MDRD) equations and three Chronic Kidney Disease Epi …
Novel glomerular filtration markers.
George JA, Gounden V. George JA, et al. Adv Clin Chem. 2019;88:91-119. doi: 10.1016/bs.acc.2018.10.005. Epub 2018 Nov 16. Adv Clin Chem. 2019. PMID: 30612608 Review.
Chronic kidney disease is currently assessed by estimated glomerular filtration rate, a mathematical construct based on creatinine or creatinine and cystatin concentration. Creatinine-based equations have improved with standardization efforts and the Modification of Diet i …
Chronic kidney disease is currently assessed by estimated glomerular filtration rate, a mathematical construct based on creatinine or creati …
Cystatin C vs creatinine eGFR in advanced CKD: an analysis of the STOP-ACEi trial.
Spencer S, Desborough R, Mehta S, Ives N, Bhandari S. Spencer S, et al. Clin Kidney J. 2024 Aug 29;17(9):sfae268. doi: 10.1093/ckj/sfae268. eCollection 2024 Sep. Clin Kidney J. 2024. PMID: 40034484 Free PMC article.
BACKGROUND: In this secondary analysis of the STOP-ACEi trial, we explored the impact of discontinuing or continuing renin-angiotensin system inhibitor therapy in people with advanced chronic kidney disease on cystatin C estimated glomerular filtration rate (eGFR). …
BACKGROUND: In this secondary analysis of the STOP-ACEi trial, we explored the impact of discontinuing or continuing renin-angiotensin syste …
Comparison of CKD-EPI Cystatin C and Creatinine Glomerular Filtration Rate Estimation Equations in Asian Indians.
Teo BW, Sabanayagam C, Liao J, Toh QC, Saw S, Wong TY, Sethi S. Teo BW, et al. Int J Nephrol. 2014;2014:746497. doi: 10.1155/2014/746497. Epub 2014 Apr 27. Int J Nephrol. 2014. PMID: 24868463 Free PMC article.
Chronic kidney disease (CKD) is identified in the general population using estimated glomerular filtration rates (eGFR) calculated from a serum creatinine-based equation, the chronic kidney disease-epidemiology collaboration (CKD-EPI) equation. Using s …
Chronic kidney disease (CKD) is identified in the general population using estimated glomerular filtration rates (eGFR) calculated from a se …
Should Cystatin C eGFR Become Routine Clinical Practice?
Spencer S, Desborough R, Bhandari S. Spencer S, et al. Biomolecules. 2023 Jul 5;13(7):1075. doi: 10.3390/biom13071075. Biomolecules. 2023. PMID: 37509111 Free PMC article. Review.
It is unaffected by muscle mass and shows stronger associations with cardiovascular disease and mortality than creatinine. Various equations have been developed to estimate GFR using creatinine or cystatin C alone or in combination. The CKD-E …
It is unaffected by muscle mass and shows stronger associations with cardiovascular disease and mortality than creatinine. Various equati …
The Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation incorporating both cystatin C and creatinine best predicts individual risk: a cohort study in 444 patients with chronic kidney disease.
Rogacev KS, Pickering JW, Seiler S, Zawada AM, Emrich I, Fliser D, Heine GH. Rogacev KS, et al. Nephrol Dial Transplant. 2014 Feb;29(2):348-55. doi: 10.1093/ndt/gft422. Epub 2013 Oct 28. Nephrol Dial Transplant. 2014. PMID: 24166454
BACKGROUND: The recently introduced CKD-EPIcreat-cys equation surpassed creatinine-based equations for GFR estimation in a large cross-sectional analysis. ...METHODS: We recruited 444 patients with CKD GFR categories 2-4 (eGFR 15-89 mL/min/1.73 m2); baseline eGFR wa …
BACKGROUND: The recently introduced CKD-EPIcreat-cys equation surpassed creatinine-based equations for GFR estimation in a lar …
Estimated glomerular filtration rates are higher when creatinine-based equations are compared with a cystatin C-based equation in coronavirus disease 2019.
Larsson AO, Hultström M, Frithiof R, Lipcsey M, Nyman U, Eriksson MB. Larsson AO, et al. Acta Anaesthesiol Scand. 2023 Feb;67(2):213-220. doi: 10.1111/aas.14173. Epub 2022 Nov 26. Acta Anaesthesiol Scand. 2023. PMID: 36400740 Free PMC article.
Creatinine and cystatin C were analyzed at admission to the ICU as part of the routine care. Creatinine-based eGFR (ml/min) was calculated using the following equations, developed in chronological order; the Cockcroft-Gault (C-G), Modified Diet in Renal Disea …
Creatinine and cystatin C were analyzed at admission to the ICU as part of the routine care. Creatinine-based eGFR (ml/min) wa …
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