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2000 1
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17 results

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Page 1
Development of Promitil, a lipidic prodrug of mitomycin c in PEGylated liposomes: From bench to bedside.
Gabizon A, Shmeeda H, Tahover E, Kornev G, Patil Y, Amitay Y, Ohana P, Sapir E, Zalipsky S. Gabizon A, et al. Adv Drug Deliv Rev. 2020;154-155:13-26. doi: 10.1016/j.addr.2020.07.027. Epub 2020 Aug 7. Adv Drug Deliv Rev. 2020. PMID: 32777239 Review.
The pharmacokinetics of MLP was typically stealth with long T (~1 day), slow clearance and small volume of distribution. Interestingly, a longer T, and slower clearance were both correlated with disease stabilization and longer survival. This association of pharm
The pharmacokinetics of MLP was typically stealth with long T (~1 day), slow clearance and small volume of distribution. Inter …
Stealth Nanocarriers in Cancer Therapy: a Comprehensive Review of Design, Functionality, and Clinical Applications.
Saadh MJ, Mustafa MA, Kumar A, Alamir HTA, Kumar A, Khudair SA, Faisal A, Alubiady MHS, Jalal SS, Shafik SS, Ahmad I, Khry FAF, Abosaoda MK. Saadh MJ, et al. AAPS PharmSciTech. 2024 Jun 18;25(6):140. doi: 10.1208/s12249-024-02843-5. AAPS PharmSciTech. 2024. PMID: 38890191 Review.
The in vivo behavior of stealth nanocarriers and their impact on pharmacokinetics, biodistribution, and toxicity were also systematically examined. Additionally, the review presented clinical applications, case studies of approved nanocarrier-based can …
The in vivo behavior of stealth nanocarriers and their impact on pharmacokinetics, biodistribution, and toxicity were also sys …
Exploring the possible targeting strategies of liposomes against methicillin-resistant Staphylococcus aureus (MRSA).
Mat Rani NNI, Mustafa Hussein Z, Mustapa F, Azhari H, Sekar M, Chen XY, Mohd Amin MCI. Mat Rani NNI, et al. Eur J Pharm Biopharm. 2021 Aug;165:84-105. doi: 10.1016/j.ejpb.2021.04.021. Epub 2021 May 8. Eur J Pharm Biopharm. 2021. PMID: 33974973 Review.
The surface of the liposomes can also be designed and enhanced with drug-release properties, active targeting, and stealth effects to prevent recognition by the mononuclear phagocyte system, thus enhancing its circulation time. The present review aimed to hig …
The surface of the liposomes can also be designed and enhanced with drug-release properties, active targeting, and stealth eff …
The Targeted-liposome Delivery System of Antitumor Drugs.
Wu WD, Yi XL, Jiang LX, Li YZ, Gao J, Zeng Y, Yi RD, Dai LP, Li W, Ci XY, Si DY, Liu CX. Wu WD, et al. Curr Drug Metab. 2015;16(10):894-910. doi: 10.2174/138920021610151210184654. Curr Drug Metab. 2015. PMID: 26652257 Review.
Here, the author reviewed the important targets for cancer therapy and the pharmacokinetic behavior of liposomal drugs in vivo, as well as the application of the targeting liposomal system in cancer therapy. Considering further application for clinical
Here, the author reviewed the important targets for cancer therapy and the pharmacokinetic behavior of liposomal drugs in vivo …
Cell membrane coated nanocarriers - an efficient biomimetic platform for targeted therapy.
Dash P, Piras AM, Dash M. Dash P, et al. J Control Release. 2020 Nov 10;327:546-570. doi: 10.1016/j.jconrel.2020.09.012. Epub 2020 Sep 8. J Control Release. 2020. PMID: 32911013 Review.
Traditional methods of delivering drugs and therapeutics faced issues of solubility, sustained release, not enough amount getting through the diseased site, for e.g a tumor. Various formulations of liposomes, polymers, dendrimers, etc have succeeded and made their way for …
Traditional methods of delivering drugs and therapeutics faced issues of solubility, sustained release, not enough amount getting through th …
From conventional to stealth liposomes: a new Frontier in cancer chemotherapy.
Cattel L, Ceruti M, Dosio F. Cattel L, et al. J Chemother. 2004 Nov;16 Suppl 4:94-7. doi: 10.1179/joc.2004.16.Supplement-1.94. J Chemother. 2004. PMID: 15688621 Review.
The first-generation liposomes (conventional liposomes) comprised a liposome-containing amphotericin B, Ambisome, and Myocet, doxorubicin-containing liposome used in clinical trials to treat metastatic breast cancer. The last generation lipos
The first-generation liposomes (conventional liposomes) comprised a liposome-containing amphotericin B, Ambisome, and M …
Stealth Engineering for In Vivo Drug Delivery Systems.
Mohapatra A, Morshed BI, Haggard WO, Smith RA. Mohapatra A, et al. Crit Rev Biomed Eng. 2015;43(5-6):347-69. doi: 10.1615/CritRevBiomedEng.2016016141. Crit Rev Biomed Eng. 2015. PMID: 27480580 Review.
Stealth-engineered DDS has been successful in extending drug circulation lifetime from a few minutes to several days. ...This review covers the progress of some types of DDS that have been published and indexed in major databases (including ScienceDirect, PubMed, an
Stealth-engineered DDS has been successful in extending drug circulation lifetime from a few minutes to several days. ...This revi
Liposomes and nanotechnology in drug development: focus on neurological targets.
Ramos-Cabrer P, Campos F. Ramos-Cabrer P, et al. Int J Nanomedicine. 2013;8:951-60. doi: 10.2147/IJN.S30721. Epub 2013 Mar 3. Int J Nanomedicine. 2013. PMID: 23486739 Free PMC article. Review.
The marriage between drug delivery and molecular imaging disciplines has resulted in a relatively new discipline, known as theranostics, which represents the basis of the concept of personalized medicine. In this study, we review the concepts of the blood-brain barrier and …
The marriage between drug delivery and molecular imaging disciplines has resulted in a relatively new discipline, known as theranostics, whi …
Advantages of liposomal delivery systems for anthracyclines.
Allen TM, Martin FJ. Allen TM, et al. Semin Oncol. 2004 Dec;31(6 Suppl 13):5-15. doi: 10.1053/j.seminoncol.2004.08.001. Semin Oncol. 2004. PMID: 15717735 Review.
Numerous strategies that seek to either exploit or avoid this phenomenon have been used. As a result, several liposomal chemotherapeutic agents are now available in the clinic. STEALTH, a novel liposomal system coated with polyethylene glycol, avoids u …
Numerous strategies that seek to either exploit or avoid this phenomenon have been used. As a result, several liposomal chemotherapeu …
Liposomal drug delivery systems: an update review.
Samad A, Sultana Y, Aqil M. Samad A, et al. Curr Drug Deliv. 2007 Oct;4(4):297-305. doi: 10.2174/156720107782151269. Curr Drug Deliv. 2007. PMID: 17979650 Review.
Most clinical applications of liposomal drug delivery are targeting to tissue with or without expression of target recognition molecules on lipid membrane. ...This review would be a help to the researchers working in the area of liposomal drug delivery …
Most clinical applications of liposomal drug delivery are targeting to tissue with or without expression of target recognition …
17 results