The critical role of ASD-related gene CNTNAP3 in regulating synaptic development and social behavior in mice.
Tong DL, Chen RG, Lu YL, Li WK, Zhang YF, Lin JK, He LJ, Dang T, Shan SF, Xu XH, Zhang Y, Zhang C, Du YS, Zhou WH, Wang X, Qiu Z.
Tong DL, et al.
Neurobiol Dis. 2019 Oct;130:104486. doi: 10.1016/j.nbd.2019.104486. Epub 2019 May 29.
Neurobiol Dis. 2019.
PMID: 31150793
We found that CNTNAP3 interacted with synaptic adhesion proteins Neuroligin1 and Neuroligin2, as well as scaffolding proteins PSD95 and Gephyrin. ...These evidences elucidate the pivotal role of CNTNAP3 in synapse development and social behaviors, providing mechanis …
We found that CNTNAP3 interacted with synaptic adhesion proteins Neuroligin1 and Neuroligin2, as well as scaffolding proteins PSD95 a …