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Year Number of Results
1986 1
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2001 4
2002 3
2003 3
2004 2
2005 3
2006 6
2007 3
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2009 5
2010 7
2011 9
2012 9
2013 4
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403 results

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Page 1
A COL5A2 In-Frame Deletion in a Chihuahua with Ehlers-Danlos Syndrome.
Kiener S, Chevallier L, Jagannathan V, Briand A, Cochet-Faivre N, Reyes-Gomez E, Leeb T. Kiener S, et al. Genes (Basel). 2022 May 23;13(5):934. doi: 10.3390/genes13050934. Genes (Basel). 2022. PMID: 35627319 Free PMC article.
Whole-genome sequencing identified a heterozygous de novo 27 bp deletion in the COL5A2 gene, COL5A2:c.3388_3414del. The in-frame deletion is predicted to remove 9 amino acids in the triple-helical region of COL5A2. The molecular analysis and identification of …
Whole-genome sequencing identified a heterozygous de novo 27 bp deletion in the COL5A2 gene, COL5A2:c.3388_3414del. The in-fra …
COL5A2 is a prognostic-related biomarker and correlated with immune infiltrates in gastric cancer based on transcriptomics and single-cell RNA sequencing.
Chen M, Zhu X, Zhang L, Zhao D. Chen M, et al. BMC Med Genomics. 2023 Sep 18;16(1):220. doi: 10.1186/s12920-023-01659-9. BMC Med Genomics. 2023. PMID: 37723519 Free PMC article.
RESULTS: COL5A2 expression was elevated in GC. More than this, the scRNA-seq analysis revealed that COL5A2 expression had a spatial gradient. ...GSEA analyses revealed that COL5A2 was associated with tumor progression-related pathways. Meanwhile, COL5A2 …
RESULTS: COL5A2 expression was elevated in GC. More than this, the scRNA-seq analysis revealed that COL5A2 expression had a sp …
COL5A2-mediated endoplasmic reticulum stress promotes macrophage M2 polarization in lung adenocarcinoma.
Sun G, Wang Y, Ni K, Shen J, Liu D, Wang H. Sun G, et al. Cell Stress Chaperones. 2025 Jul;30(4):100081. doi: 10.1016/j.cstres.2025.100081. Epub 2025 May 7. Cell Stress Chaperones. 2025. PMID: 40345640 Free PMC article.
Therefore, this study aims to investigate the regulatory mechanism of COL5A2 in mediating macrophage M2 polarization in LUAD. We analyzed COL5A2 expression in LUAD samples from the TCGA-LUAD database. Using GSEA, we sought to identify the signaling pathways influenc …
Therefore, this study aims to investigate the regulatory mechanism of COL5A2 in mediating macrophage M2 polarization in LUAD. We anal …
COL5A2 as a potential clinical biomarker for gastric cancer and renal metastasis.
Ding YL, Sun SF, Zhao GL. Ding YL, et al. Medicine (Baltimore). 2021 Feb 19;100(7):e24561. doi: 10.1097/MD.0000000000024561. Medicine (Baltimore). 2021. PMID: 33607786 Free PMC article.
Through the ROC result, COL5A2 had more advantage as a biomarker for GC than other collagens. CONCLUSIONS: COL5A2 gene expression level might be a risk factor for GC. COL5A2 has a strong correlation with the prognosis of the disease....
Through the ROC result, COL5A2 had more advantage as a biomarker for GC than other collagens. CONCLUSIONS: COL5A2 gene express …
Phenotype of COL3A1/COL5A2 deletion patients.
Kempers MJ, Wessels M, Van Berendoncks A, van de Laar IM, de Leeuw N, Loeys B. Kempers MJ, et al. Eur J Med Genet. 2022 Oct;65(10):104593. doi: 10.1016/j.ejmg.2022.104593. Epub 2022 Aug 11. Eur J Med Genet. 2022. PMID: 35964930 Free article.
Classical (cEDS) and vascular type (vEDS) are the most prevalent subtypes and are caused by heterozygous pathogenic variants in COL5A1, COL5A2, COL1A1 or, respectively, in COL3A1. We describe 3 cases with contiguous deletions resulting in haploinsufficiency of both genes w …
Classical (cEDS) and vascular type (vEDS) are the most prevalent subtypes and are caused by heterozygous pathogenic variants in COL5A1, C …
CHSY3 promotes proliferation and migration in gastric cancer and is associated with immune infiltration.
Huang X, Liu Y, Qian C, Shen Q, Wu M, Zhu B, Feng Y. Huang X, et al. J Transl Med. 2023 Jul 17;21(1):474. doi: 10.1186/s12967-023-04333-x. J Transl Med. 2023. PMID: 37461041 Free PMC article.
Then, utilizing WGCNA, the PPI network constructed by Cytoscape, and random forest model, the Hub genes of COL5A2, POSTN, COL1A1, and FN1 associated with immunity were screened. Finally, the expression of CHSY3 in GC tissues was verified by qRT-PCR and immunohistochemical …
Then, utilizing WGCNA, the PPI network constructed by Cytoscape, and random forest model, the Hub genes of COL5A2, POSTN, COL1A1, and …
COL5A2 drives regorafenib resistance-induced metastatic phenotype via reducing LIFR expression in hepatocellular carcinoma.
Zhang S, Xue X, Chen F, Yang Y, Zhang N, Chen Y, Wu W, Wang J, Zheng N. Zhang S, et al. Acta Biochim Biophys Sin (Shanghai). 2024 May 30;56(7):997-1010. doi: 10.3724/abbs.2024058. Acta Biochim Biophys Sin (Shanghai). 2024. PMID: 38818582 Free PMC article.
Here, we conduct transcriptome sequencing analysis to identify COL5A2 as a crucial driver of the metastatic characteristics of regorafenib-resistant HCC cells. ...Interestingly, rescue experiments show that the inhibition of the above aggressive features of resistant cells …
Here, we conduct transcriptome sequencing analysis to identify COL5A2 as a crucial driver of the metastatic characteristics of regora …
COL5A2 Inhibits the TGF-beta and Wnt/beta-Catenin Signaling Pathways to Inhibit the Invasion and Metastasis of Osteosarcoma.
Han YL, Luo D, Habaxi K, Tayierjiang J, Zhao W, Wang W, Aikebaier W, Wang L. Han YL, et al. Front Oncol. 2022 Feb 24;12:813809. doi: 10.3389/fonc.2022.813809. eCollection 2022. Front Oncol. 2022. PMID: 35280775 Free PMC article.
Furthermore, qRT-PCR and immunofluorescence assays confirmed the high expression of COL5A2 in human osteosarcoma cells. CCK-8 assay and scratch WB was used to determine whether the downregulation of COL5A2 expression inhibits the TGF-beta signaling and Wnt/beta-Cate …
Furthermore, qRT-PCR and immunofluorescence assays confirmed the high expression of COL5A2 in human osteosarcoma cells. CCK-8 assay a …
Integrative Analysis From Multicenter Studies Identifies a WGCNA-Derived Cancer-Associated Fibroblast Signature for Ovarian Cancer.
Feng S, Xu Y, Dai Z, Yin H, Zhang K, Shen Y. Feng S, et al. Front Immunol. 2022 Jul 8;13:951582. doi: 10.3389/fimmu.2022.951582. eCollection 2022. Front Immunol. 2022. PMID: 35874760 Free PMC article.
A machine learning methodology was used to identify COL16A1, COL5A2, GREM1, LUM, SRPX, and TIMP3 and construct a prognostic signature. Subsequently, a series of bioinformatics algorithms indicated risk stratification based on the above signature, suggesting that high-risk …
A machine learning methodology was used to identify COL16A1, COL5A2, GREM1, LUM, SRPX, and TIMP3 and construct a prognostic signature …
COL5A2 Promotes Proliferation and Invasion in Prostate Cancer and Is One of Seven Gleason-Related Genes That Predict Recurrence-Free Survival.
Ren X, Chen X, Fang K, Zhang X, Wei X, Zhang T, Li G, Lu Z, Song N, Wang S, Qin C. Ren X, et al. Front Oncol. 2021 Mar 18;11:583083. doi: 10.3389/fonc.2021.583083. eCollection 2021. Front Oncol. 2021. PMID: 33816226 Free PMC article.
Weighted correlation network analysis (WGCNA) was used, and COL5A2 was selected for further analysis. The results from in vitro experiments demonstrated that COL5A2 was upregulated in PCa with high Gleason scores. The knockdown of COL5A2 inhibited cell prolif …
Weighted correlation network analysis (WGCNA) was used, and COL5A2 was selected for further analysis. The results from in vitro exper …
403 results