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Page 1
COVID-19 Coronavirus Vaccine Design Using Reverse Vaccinology and Machine Learning.
Ong E, Wong MU, Huffman A, He Y. Ong E, et al. Among authors: he y. Front Immunol. 2020 Jul 3;11:1581. doi: 10.3389/fimmu.2020.01581. eCollection 2020. Front Immunol. 2020. PMID: 32719684 Free PMC article.
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. ...We then applied the Vaxign and the newly developed …
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highl …
COVID-19 vaccine design using reverse and structural vaccinology, ontology-based literature mining and machine learning.
Huffman A, Ong E, Hur J, D'Mello A, Tettelin H, He Y. Huffman A, et al. Among authors: he y. Brief Bioinform. 2022 Jul 18;23(4):bbac190. doi: 10.1093/bib/bbac190. Brief Bioinform. 2022. PMID: 35649389 Free PMC article.
Rational vaccine design, especially vaccine antigen identification and optimization, is critical to successful and efficient vaccine development against various infectious diseases including coronavirus disease 2019 (COVID-19). In general, computational vacci …
Rational vaccine design, especially vaccine antigen identification and optimization, is critical to successful and efficient vaccine develop …
Profiling COVID-19 Vaccine Adverse Events by Statistical and Ontological Analysis of VAERS Case Reports.
Guo W, Deguise J, Tian Y, Huang PC, Goru R, Yang Q, Peng S, Zhang L, Zhao L, Xie J, He Y. Guo W, et al. Among authors: he y. Front Pharmacol. 2022 Jun 24;13:870599. doi: 10.3389/fphar.2022.870599. eCollection 2022. Front Pharmacol. 2022. PMID: 35814246 Free PMC article.
Since the beginning of the COVID-19 pandemic, vaccines have been developed to mitigate the spread of SARS-CoV-2, the virus that causes COVID-19. ...Using VAERS data as of 31 December 2021, 96 AEs were found to be statistically sign …
Since the beginning of the COVID-19 pandemic, vaccines have been developed to mitigate the spread of SARS-CoV- …
Differential COVID-19 Symptoms Given Pandemic Locations, Time, and Comorbidities During the Early Pandemic.
Wang Y, Zhang F, Byrd JB, Yu H, Ye X, He Y. Wang Y, et al. Among authors: he y. Front Med (Lausanne). 2022 Jan 28;9:770031. doi: 10.3389/fmed.2022.770031. eCollection 2022. Front Med (Lausanne). 2022. PMID: 35155491 Free PMC article.
In this study, we systematically extracted and analyzed clinical phenotypes and comorbidities in COVID-19 patients found at different countries and regions during the early pandemic using an ontology-based bioinformatics approach, with the aim to identify new insigh …
In this study, we systematically extracted and analyzed clinical phenotypes and comorbidities in COVID-19 patients found at di …
Cov19VaxKB: A Web-based Integrative COVID-19 Vaccine Knowledge Base.
Huang PC, Goru R, Huffman A, Yu Lin A, Cooke MF, He Y. Huang PC, et al. Among authors: he y. Vaccine X. 2021 Dec 28;10:100139. doi: 10.1016/j.jvacx.2021.100139. Online ahead of print. Vaccine X. 2021. PMID: 34981039 Free PMC article.
The development of SARS-CoV-2 vaccines during the COVID-19 pandemic has prompted the emergence of COVID-19 vaccine data. ...Cov19VaxKB features comprehensive lists of COVID-19 vaccines, vaccine formulations, cl …
The development of SARS-CoV-2 vaccines during the COVID-19 pandemic has prompted the emergence of COVI …
COVID-19-associated AKI in hospitalized US patients: incidence, temporal trends, geographical distribution, risk factors and mortality.
Yoo YJ, Wilkins KJ, Alakwaa F, Liu F, Torre-Healy LA, Krichevsky S, Hong SS, Sakhuja A, Potu CK, Saltz JH, Saran R, Zhu RL, Setoguchi S, Kane-Gill SL, Mallipattu SK, He Y, Ellison DH, Byrd JB, Parikh CR, Moffitt RA, Koraishy FM; Consortial Authors:. Yoo YJ, et al. Among authors: he y. medRxiv [Preprint]. 2022 Sep 2:2022.09.02.22279398. doi: 10.1101/2022.09.02.22279398. medRxiv. 2022. PMID: 36093355 Free PMC article. Preprint.
We selected hospitalized adults diagnosed with COVID-19 between March 6th, 2020, and January 6th, 2022. AKI was determined with serum creatinine (SCr) and diagnosis codes. ...In multivariable models, AKI defined by either SCr or diagnostic code, and the severity of …
We selected hospitalized adults diagnosed with COVID-19 between March 6th, 2020, and January 6th, 2022. AKI was determined wit …
A community effort for COVID-19 Ontology Harmonization.
Lin AY, Yamagata Y, Duncan WD, Carmody LC, Kushida T, Masuya H, Beverley J, Dutta B, DeBellis M, Pendlington ZM, Roncaglia P, He Y. Lin AY, et al. Among authors: he y. CEUR Workshop Proc. 2022;3073:122-127. Epub 2022 Jan 28. CEUR Workshop Proc. 2022. PMID: 37324543 Free PMC article.
Ontologies have emerged to become critical to support data and knowledge representation, standardization, integration, and analysis. The SARS-CoV-2 pandemic led to the rapid proliferation of COVID-19 data, as well as the development of many C …
Ontologies have emerged to become critical to support data and knowledge representation, standardization, integration, and analysis. The …
COVID-19 coronavirus vaccine design using reverse vaccinology and machine learning.
Ong E, Wong MU, Huffman A, He Y. Ong E, et al. Among authors: he y. bioRxiv [Preprint]. 2020 Mar 22:2020.03.20.000141. doi: 10.1101/2020.03.20.000141. bioRxiv. 2020. Update in: Front Immunol. 2020 Jul 03;11:1581. doi: 10.3389/fimmu.2020.01581. PMID: 32511333 Free PMC article. Updated. Preprint.
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highly contagious disease caused by the SARS-CoV-2 coronavirus. ...Besides the commonly used S protein, the nsp3 prot …
To ultimately combat the emerging COVID-19 pandemic, it is desired to develop an effective and safe vaccine against this highl …
Evaluating the safety of XBB.1.5-containing COVID-19 mRNA vaccines using a self-controlled case series study.
Pan Y, Han Y, Zhou C, Zhao L, Zheng J, Ye X, He Y; N3C Consortium. Pan Y, et al. Among authors: he y. Nat Commun. 2025 Jul 15;16(1):6514. doi: 10.1038/s41467-025-61613-4. Nat Commun. 2025. PMID: 40664645 Free PMC article.
The safety of XBB.1.5-containing COVID-19 mRNA vaccines warrants investigation. We assessed the relative risk of 15 adverse events following the XBB.1.5 vaccination using a self-controlled case series study design with data from the National COVID Cohort Collaborati …
The safety of XBB.1.5-containing COVID-19 mRNA vaccines warrants investigation. We assessed the relative risk of 15 adverse ev …
39 results