Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2002 1
2003 1
2004 1
2005 5
2006 5
2007 15
2008 25
2009 36
2010 50
2011 86
2012 139
2013 307
2014 637
2015 1252
2016 2186
2017 3141
2018 4129
2019 5115
2020 6015
2021 6843
2022 7436
2023 7196
2024 72

Text availability

Article attribute

Article type

Publication date

Search Results

40,763 results

Results by year

Filters applied: . Clear all
Page 1
Did you mean crisp[Title/Abstract] (1,648 results)?
Genome modification by CRISPR/Cas9.
Ma Y, Zhang L, Huang X. Ma Y, et al. FEBS J. 2014 Dec;281(23):5186-93. doi: 10.1111/febs.13110. Epub 2014 Nov 7. FEBS J. 2014. PMID: 25315507 Free article. Review.
Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein (Cas)9-mediated genome modification enables us to edit the genomes of a variety of organisms rapidly and efficiently. ...We will also discuss the potential applications of …
Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated protein (Cas)9-mediated genome modificati …
Current applications and future perspective of CRISPR/Cas9 gene editing in cancer.
Wang SW, Gao C, Zheng YM, Yi L, Lu JC, Huang XY, Cai JB, Zhang PF, Cui YH, Ke AW. Wang SW, et al. Mol Cancer. 2022 Feb 21;21(1):57. doi: 10.1186/s12943-022-01518-8. Mol Cancer. 2022. PMID: 35189910 Free PMC article. Review.
This system inspires the development of a powerful genome engineering tool, the CRISPR/CRISPR-associated nuclease 9 (CRISPR/Cas9) genome editing system. ...Here, we review current status of CRISPR/Cas9 gene editing technology in oncological research. W …
This system inspires the development of a powerful genome engineering tool, the CRISPR/CRISPR-associated nuclease 9 (CRISPR
CRISPR-Cas bioinformatics.
Alkhnbashi OS, Meier T, Mitrofanov A, Backofen R, Voß B. Alkhnbashi OS, et al. Methods. 2020 Feb 1;172:3-11. doi: 10.1016/j.ymeth.2019.07.013. Epub 2019 Jul 19. Methods. 2020. PMID: 31326596 Review.
In recent years, the CRISPR-Cas system has also been engineered to facilitate target gene editing in eukaryotic genomes. Bioinformatics played an essential role in the detection and analysis of CRISPR systems and here we review the bioinformatics-based efforts that …
In recent years, the CRISPR-Cas system has also been engineered to facilitate target gene editing in eukaryotic genomes. Bioinformati …
The Biology of CRISPR-Cas: Backward and Forward.
Hille F, Richter H, Wong SP, Bratovič M, Ressel S, Charpentier E. Hille F, et al. Cell. 2018 Mar 8;172(6):1239-1259. doi: 10.1016/j.cell.2017.11.032. Cell. 2018. PMID: 29522745 Free article. Review.
In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) proteins constitute an adaptive immune system against phages and other foreign genetic elements. Here, we review the biology of the diverse CRI
In bacteria and archaea, clustered regularly interspaced short palindromic repeats (CRISPR) and CRISPR-associated (Cas) protei …
Controlling and enhancing CRISPR systems.
Shivram H, Cress BF, Knott GJ, Doudna JA. Shivram H, et al. Nat Chem Biol. 2021 Jan;17(1):10-19. doi: 10.1038/s41589-020-00700-7. Epub 2020 Dec 16. Nat Chem Biol. 2021. PMID: 33328654 Free PMC article. Review.
Many bacterial and archaeal organisms use clustered regularly interspaced short palindromic repeats-CRISPR associated (CRISPR-Cas) systems to defend themselves from mobile genetic elements. ...To realize their full potential, it is important to control the timing, d …
Many bacterial and archaeal organisms use clustered regularly interspaced short palindromic repeats-CRISPR associated (CRISPR- …
Diverse virus-encoded CRISPR-Cas systems include streamlined genome editors.
Al-Shayeb B, Skopintsev P, Soczek KM, Stahl EC, Li Z, Groover E, Smock D, Eggers AR, Pausch P, Cress BF, Huang CJ, Staskawicz B, Savage DF, Jacobsen SE, Banfield JF, Doudna JA. Al-Shayeb B, et al. Cell. 2022 Nov 23;185(24):4574-4586.e16. doi: 10.1016/j.cell.2022.10.020. Cell. 2022. PMID: 36423580 Free article.
CRISPR-Cas systems are host-encoded pathways that protect microbes from viral infection using an adaptive RNA-guided mechanism. ...Bacteriophage-encoded CRISPR systems belong to all six known CRISPR-Cas types, though some lack crucial components, suggesting a
CRISPR-Cas systems are host-encoded pathways that protect microbes from viral infection using an adaptive RNA-guided mechanism. ...Ba
Cancer CRISPR Screens In Vivo.
Chow RD, Chen S. Chow RD, et al. Trends Cancer. 2018 May;4(5):349-358. doi: 10.1016/j.trecan.2018.03.002. Epub 2018 Mar 30. Trends Cancer. 2018. PMID: 29709259 Free PMC article. Review.
Clustered regularly interspaced short palindromic repeats (CRISPR) screening is a powerful toolset for investigating diverse biological processes. Most CRISPR screens to date have been performed with in vitro cultures or cellular transplant models. ...
Clustered regularly interspaced short palindromic repeats (CRISPR) screening is a powerful toolset for investigating diverse biologic …
Lipid-Nanoparticle-Based Delivery of CRISPR/Cas9 Genome-Editing Components.
Kazemian P, Yu SY, Thomson SB, Birkenshaw A, Leavitt BR, Ross CJD. Kazemian P, et al. Mol Pharm. 2022 Jun 6;19(6):1669-1686. doi: 10.1021/acs.molpharmaceut.1c00916. Epub 2022 May 20. Mol Pharm. 2022. PMID: 35594500 Free PMC article. Review.
In this review, we provide a background of CRISPR-mediated gene therapy, as well as LNPs and their applicable characteristics for delivering CRISPR components. ...Finally, we discuss considerations for using LNPs to deliver CRISPR and future perspectives on c …
In this review, we provide a background of CRISPR-mediated gene therapy, as well as LNPs and their applicable characteristics for del …
Applications of CRISPR as a potential therapeutic.
Luthra R, Kaur S, Bhandari K. Luthra R, et al. Life Sci. 2021 Nov 1;284:119908. doi: 10.1016/j.lfs.2021.119908. Epub 2021 Aug 25. Life Sci. 2021. PMID: 34453943 Review.
CRISPR-based therapy is also being researched and defined for COVID-19. The related mechanism of CRISPR has been discussed alongside highlighting challenges involved in therapeutic applications of CRISPR....
CRISPR-based therapy is also being researched and defined for COVID-19. The related mechanism of CRISPR has been discussed alo
CRISPR/Cas9 for cancer treatment: technology, clinical applications and challenges.
Cheng X, Fan S, Wen C, Du X. Cheng X, et al. Brief Funct Genomics. 2020 May 20;19(3):209-214. doi: 10.1093/bfgp/elaa001. Brief Funct Genomics. 2020. PMID: 32052006 Review.
Clustered regularly interspaced short palindromic repeats (CRISPR) is described as RNA mediated adaptive immune system defense, which is naturally found in bacteria and archaea. ...Then, we summarize these preclinical CRISPR-Cas9-based therapeutic strategies against …
Clustered regularly interspaced short palindromic repeats (CRISPR) is described as RNA mediated adaptive immune system defense, which …
40,763 results
You have reached the last available page of results. Please see the User Guide for more information.