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A brief review of complex regional pain syndrome and current management.
Abd-Elsayed A, Stark CW, Topoluk N, Isaamullah M, Uzodinma P, Viswanath O, Gyorfi MJ, Fattouh O, Schlidt KC, Dyara O. Abd-Elsayed A, et al. Ann Med. 2024 Dec;56(1):2334398. doi: 10.1080/07853890.2024.2334398. Epub 2024 Apr 3. Ann Med. 2024. PMID: 38569195 Free PMC article. Review.
Current management directed at this disease is broad and growing, ranging from non-invasive modalities such as physical and psychological therapy to more invasive techniques such as dorsal root ganglion stimulation and potentially amputation. Ideal the …
Current management directed at this disease is broad and growing, ranging from non-invasive modalities such as physical and psychological th …
Complex Regional Pain Syndrome: Diagnosis, Pathophysiology, and Treatment Approaches.
Lima Pessôa B, Netto JGM, Adolphsson L, Longo L, Hauwanga WN, McBenedict B. Lima Pessôa B, et al. Cureus. 2024 Dec 24;16(12):e76324. doi: 10.7759/cureus.76324. eCollection 2024 Dec. Cureus. 2024. PMID: 39850174 Free PMC article. Review.
Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by significant sensory, motor, and autonomic dysfunction, often following trauma or nerve injury. ...In refractory cases, interventional modalities like spinal cord stimulation
Complex regional pain syndrome (CRPS) is a chronic pain condition characterized by significant sensory, motor, and autonomic dysfunct …
Continuous electrical stimulation of the dorsal root ganglion (drg-s) as a salvation therapy in patients previously treated with spinal cord stimulation. systematic review and pooled analysis.
Acevedo-Gonzalez JC, Lacouture-Silgado I. Acevedo-Gonzalez JC, et al. Neurosurg Rev. 2025 Sep 22;48(1):660. doi: 10.1007/s10143-025-03769-7. Neurosurg Rev. 2025. PMID: 40982036 Free PMC article.
BACKGROUND CONTEXT: Treatment techniques on the dorsal root ganglion has offered a broad overview in the chronic pain. The aim is to review the existing evidence on DRG-s as a "salvation" of spinal cord stimulation therapies. ...In the ph …
BACKGROUND CONTEXT: Treatment techniques on the dorsal root ganglion has offered a broad overview in the chronic pain. …
Cost-Effectiveness of Dorsal Root Ganglion Stimulation or Spinal Cord Stimulation for Complex Regional Pain Syndrome.
Mekhail N, Deer TR, Poree L, Staats PS, Burton AW, Connolly AT, Karst E, Mehanny DS, Saweris Y, Levy RM. Mekhail N, et al. Neuromodulation. 2021 Jun;24(4):708-718. doi: 10.1111/ner.13134. Epub 2020 Mar 9. Neuromodulation. 2021. PMID: 32153073
OBJECTIVES: ACCURATE, a randomized controlled trial, compared safety and effectiveness of stimulation of the dorsal root ganglion (DRG) vs. conventional spinal cord stimulation (SCS) in complex regional pain syndrome (CRPS-I …
OBJECTIVES: ACCURATE, a randomized controlled trial, compared safety and effectiveness of stimulation of the dorsal root
Modern Principles of Diagnosis and Treatment in Complex Regional Pain Syndrome.
Melf-Marzi A, Böhringer B, Wiehle M, Hausteiner-Wiehle C. Melf-Marzi A, et al. Dtsch Arztebl Int. 2022 Dec 27;119(51-52):879-886. doi: 10.3238/arztebl.m2022.0358. Dtsch Arztebl Int. 2022. PMID: 36482756 Free PMC article.
METHODS: Method: Based on a selective search of the literature, we summarize current principles for the diagnosis and treatment of CRPS. RESULTS: Results: Regional findings in CRPS are accompanied by systemic symptoms, especially by neurocognitive disorders of body …
METHODS: Method: Based on a selective search of the literature, we summarize current principles for the diagnosis and treatment of CRPS
The Analgesic Efficacy of Therapies Used for Complex Regional Pain Syndrome: A Systematic Review.
Shekarsarai C, McQuibban NA, Gullick N. Shekarsarai C, et al. Cureus. 2025 Sep 6;17(9):e91697. doi: 10.7759/cureus.91697. eCollection 2025 Sep. Cureus. 2025. PMID: 40917914 Free PMC article. Review.
Pain exposure physical therapy (PEPT) improved range of motion but had a limited impact on overall functional outcomes. Neuromodulation methods, including spinal cord stimulation (SCS), dorsal root ganglion (DRG) stimulation, and t …
Pain exposure physical therapy (PEPT) improved range of motion but had a limited impact on overall functional outcomes. Neuromodulation meth …
Paresthesia-Free Dorsal Root Ganglion Stimulation: An ACCURATE Study Sub-Analysis.
Mekhail N, Deer TR, Kramer J, Poree L, Amirdelfan K, Grigsby E, Staats P, Burton AW, Burgher AH, Scowcroft J, Golovac S, Kapural L, Paicius R, Pope J, Samuel S, McRoberts WP, Schaufele M, Kent AR, Raza A, Levy RM. Mekhail N, et al. Neuromodulation. 2020 Feb;23(2):185-195. doi: 10.1111/ner.12942. Epub 2019 Mar 12. Neuromodulation. 2020. PMID: 30861286 Clinical Trial.
INTRODUCTION: ACCURATE, a randomized controlled trial comparing dorsal root ganglion (DRG) stimulation to spinal cord stimulation, showed that DRG stimulation is a safe and effective therapy in individuals with lower extremi …
INTRODUCTION: ACCURATE, a randomized controlled trial comparing dorsal root ganglion (DRG) stimulation to spi
Cervical dorsal root ganglion stimulation for complex regional pain syndrome: Technical description and results of seven cases.
Rosado Caracena R, Mendiola de la Osa A, Rincón Higuera A, Abad Fau de Casajuana E, Ruiz Córdoba G, García de Lucas F. Rosado Caracena R, et al. Pain Pract. 2023 Mar;23(3):242-251. doi: 10.1111/papr.13183. Epub 2022 Nov 25. Pain Pract. 2023. PMID: 36380700
Dorsal root ganglion (DRG) stimulation has demonstrated better results than conventional spinal cord stimulation (SCS) for patients with CRPS in lower limbs. ...DISCUSSION: The results for cervical DRG stimulation are
Dorsal root ganglion (DRG) stimulation has demonstrated better results than conventional spinal cord
Therapy Habituation at 12 Months: Spinal Cord Stimulation Versus Dorsal Root Ganglion Stimulation for Complex Regional Pain Syndrome Type I and II.
Levy RM, Mekhail N, Kramer J, Poree L, Amirdelfan K, Grigsby E, Staats P, Burton AW, Burgher AH, Scowcroft J, Golovac S, Kapural L, Paicius R, Pope J, Samuel S, McRoberts WP, Schaufele M, Kent AR, Raza A, Deer TR. Levy RM, et al. J Pain. 2020 Mar-Apr;21(3-4):399-408. doi: 10.1016/j.jpain.2019.08.005. Epub 2019 Sep 5. J Pain. 2020. PMID: 31494275 Free article. Clinical Trial.
The ACCURATE randomized, controlled trial compared outcomes of dorsal root ganglion (DRG) stimulation versus tonic spinal cord stimulation (SCS) in 152 subjects with chronic lower extremity pain due to complex regional pain syndrom …
The ACCURATE randomized, controlled trial compared outcomes of dorsal root ganglion (DRG) stimulation versus ton …
Utilization of Concurrent Dorsal Root Ganglion Stimulation and Dorsal Column Spinal Cord Stimulation in Complex Regional Pain Syndrome.
Ghosh P, Gungor S. Ghosh P, et al. Neuromodulation. 2021 Jun;24(4):769-773. doi: 10.1111/ner.13144. Epub 2020 Mar 11. Neuromodulation. 2021. PMID: 32162402
INTRODUCTION: Complex regional pain syndrome (CRPS) can be effectively treated with spinal cord stimulation (t-SCS). There is also evidence that dorsal root ganglion (DRG) stimulation may be superior to t-SCS in CRPS. …
INTRODUCTION: Complex regional pain syndrome (CRPS) can be effectively treated with spinal cord stimulation (t-S …
59 results