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16 results

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Page 1
Clinical Effect of the Acrylonitrile-Co-Methallyl Sulfonate Surface-Treated Membrane as a Cytokine Adsorption Therapy for Sepsis due to Acute Panperitonitis: A Retrospective Cohort Study.
Hayashi K, Sasabuchi Y, Matsui H, Nakajima M, Ohbe H, Ono K, Yasunaga H. Hayashi K, et al. Blood Purif. 2020;49(3):364-371. doi: 10.1159/000504560. Epub 2020 Jan 15. Blood Purif. 2020. PMID: 31940608
METHODS: Using the Diagnosis Procedure Combination database, we identified adult patients with sepsis due to panperitonitis receiving any CRRT. Propensity score matching was used to compare patients who received CRRT with the AN69ST membrane (AN69ST gr …
METHODS: Using the Diagnosis Procedure Combination database, we identified adult patients with sepsis due to panperitonitis receiving any …
AN69ST membranes adsorb nafamostat mesylate and affect the management of anticoagulant therapy: a retrospective study.
Hirayama T, Nosaka N, Okawa Y, Ushio S, Kitamura Y, Sendo T, Ugawa T, Nakao A. Hirayama T, et al. J Intensive Care. 2017 Jul 18;5:46. doi: 10.1186/s40560-017-0244-x. eCollection 2017. J Intensive Care. 2017. PMID: 28729905 Free PMC article.
BACKGROUND: In Japan, nafamostat mesylate (NM) is frequently used as an anticoagulant during continuous renal replacement therapy (CRRT). The dialyzer membrane AN69ST has been reported to adsorb NM and affect the management of anticoagulant therapy. ...This may have …
BACKGROUND: In Japan, nafamostat mesylate (NM) is frequently used as an anticoagulant during continuous renal replacement therapy (CRRT …
Comparison of the cytokine adsorption ability in continuous renal replacement therapy using polyethyleneimine-coated polyacrylonitrile (AN69ST) or polymethylmethacrylate (PMMA) hemofilters: a pilot single-center open-label randomized control trial.
Nakamura Y, Hatomoto H, Yamasaki S, Yamauchi K, Kiyomi F, Hoshino K, Kawano Y, Nakano T, Hasegawa T, Ishikura H. Nakamura Y, et al. Eur J Med Res. 2023 Jun 30;28(1):208. doi: 10.1186/s40001-023-01184-6. Eur J Med Res. 2023. PMID: 37391846 Free PMC article. Clinical Trial.
Primary outcome data were available for 26 patients each in the AN69ST-CRRT and PMMA-CRRT arms. The CHA of high-mobility group box 1, tumor necrosis factor, interleukin (IL)-8, monokine induced by interferon-gamma, and macrophage inflammatory protein were sig …
Primary outcome data were available for 26 patients each in the AN69ST-CRRT and PMMA-CRRT arms. The CHA of high-mobilit …
The Superiority of AN69ST Membrane in the Adsorption of Fibroblast Growth Factor-23.
Minematsu Y, Yamato M, Ikemiya Y, Ito T. Minematsu Y, et al. Clin Lab. 2016;62(1-2):219-25. doi: 10.7754/clin.lab.2015.150717. Clin Lab. 2016. PMID: 27012053
CONCLUSIONS: We found an AN69ST membrane has a greater capacity for FGF-23 adsorption than two other membranes tested. Although this is an in vitro study, we believe the present findings indicate an exciting new direction in the treatment of septic AKI and highlight the ne …
CONCLUSIONS: We found an AN69ST membrane has a greater capacity for FGF-23 adsorption than two other membranes tested. Although this …
Additive effectiveness of acrylonitrile-co-methallyl sulfonate surface-treated membranes in the treatment of pneumonia: A propensity score-matched retrospective cohort study.
Hayashi K, Sasabuchi Y, Matsui H, Nakajima M, Ohbe H, Fushimi K, Ono K, Yasunaga H. Hayashi K, et al. Artif Organs. 2023 Feb;47(2):408-416. doi: 10.1111/aor.14435. Epub 2022 Nov 8. Artif Organs. 2023. PMID: 36310400 Free PMC article.
BACKGROUND: The acrylonitrile-co-methallyl sulfonate surface-treated (AN69ST) membrane has cytokine adsorption capacity and is used for treating sepsis. This study aimed to compare the effects of continuous renal replacement therapy (CRRT) using the AN69ST me …
BACKGROUND: The acrylonitrile-co-methallyl sulfonate surface-treated (AN69ST) membrane has cytokine adsorption capacity and is used f …
Associations of Polyethylenimine-Coated AN69ST Membrane in Continuous Renal Replacement Therapy with the Intensive Care Outcomes: Observations from a Claims Database from Japan.
Doi K, Iwagami M, Yoshida E, Marshall MR. Doi K, et al. Blood Purif. 2017;44(3):184-192. doi: 10.1159/000476052. Epub 2017 Jun 14. Blood Purif. 2017. PMID: 28609776 Free PMC article.
BACKGROUND/AIMS: Polyethylenimine-coated polyacrylonitrile (AN69ST) membrane is expected to improve the outcomes of critically ill patients treated by continuous renal replacement therapy (CRRT). ...CONCLUSION: This retrospective observational study suggested that …
BACKGROUND/AIMS: Polyethylenimine-coated polyacrylonitrile (AN69ST) membrane is expected to improve the outcomes of critically ill pa …
Comparison of the circulatory effects of continuous renal replacement therapy using AN69ST and polysulfone membranes in septic shock patients: A retrospective observational study.
Shibata M, Miyamoto K, Kato S. Shibata M, et al. Ther Apher Dial. 2020 Oct;24(5):561-567. doi: 10.1111/1744-9987.13462. Epub 2020 Jan 21. Ther Apher Dial. 2020. PMID: 31837077
However, the clinical literature on AN69ST membranes is very limited. We aimed to compare the circulatory effects of continuous renal replacement therapy (CRRT) between patients using the AN69ST membrane and polysulfone (PS) membrane (a nonadsorbing membrane) …
However, the clinical literature on AN69ST membranes is very limited. We aimed to compare the circulatory effects of continuous renal …
The Effect of Continuous Renal Replacement Therapy with the AN69ST Membrane on Inflammatory Markers and the Level of Consciousness of Hemodialysis Patients with Stroke: Comparison with Hemodialysis with Low Blood Flow Rate.
Matsui T, Nakagawa T, Kikuchi H, Horio H, Hashimura K. Matsui T, et al. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2018 Dec 1;39(2-3):29-35. doi: 10.2478/prilozi-2018-0039. Pril (Makedon Akad Nauk Umet Odd Med Nauki). 2018. PMID: 30864363 Free article.
MATERIAL AND METHODS: We developed a novel protocol for performing CRRT with the AN69ST membrane, which has excellent adsorption capacity for various cytokines. ...No significant changes were observed in WBC and platelet counts after 1 week of treatment in either gr …
MATERIAL AND METHODS: We developed a novel protocol for performing CRRT with the AN69ST membrane, which has excellent adsorpti …
The Role and Clinical Application of Novel Filters in Sepsis-Associated Acute Kidney Injury Blood Purification.
Deng C, Zhang W, Liu Y, Zhang H, Li Z. Deng C, et al. Ther Apher Dial. 2026 Apr;30(2):119-134. doi: 10.1111/1744-9987.70085. Epub 2025 Oct 2. Ther Apher Dial. 2026. PMID: 41036579 Review.
This review assesses the mechanisms and clinical applications of novel filters such as the oXiris filter, AN69ST membrane, CytoSorb, Hemopurifier, and others, focusing on their effectiveness in eliminating toxins and inflammatory mediators. ...Furthermore, the integration …
This review assesses the mechanisms and clinical applications of novel filters such as the oXiris filter, AN69ST membrane, CytoSorb, …
The 28-day survival rates of two cytokine-adsorbing hemofilters for continuous renal replacement therapy: a single-center retrospective comparative study.
Kobashi S, Maruhashi T, Nakamura T, Hatabayashi E, Kon A. Kobashi S, et al. Acute Med Surg. 2018 Dec 13;6(1):60-67. doi: 10.1002/ams2.382. eCollection 2019 Jan. Acute Med Surg. 2018. PMID: 30651999 Free PMC article.
Two filter types, namely polymethyl methacrylate (PMMA) and surface-treated AN69 (AN69ST) hemofilters, have been successfully used for CRRT, but no direct comparisons have been published to date. This study compared the efficacy, as measured by 28-day survival rates …
Two filter types, namely polymethyl methacrylate (PMMA) and surface-treated AN69 (AN69ST) hemofilters, have been successfully used fo …
16 results