Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1990 1
1993 1
1994 1
1996 1
1997 1
1999 4
2000 1
2001 1
2002 1
2003 3
2004 1
2005 4
2006 6
2007 4
2010 1
2011 1
2012 2
2013 5
2014 4
2015 3
2016 3
2017 4
2018 13
2019 6
2020 8
2021 13
2022 15
2023 10
2024 8
2025 13

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

129 results

Results by year

Filters applied: . Clear all
Page 1
The role of CSDE1 in translational reprogramming and human diseases.
Guo AX, Cui JJ, Wang LY, Yin JY. Guo AX, et al. Cell Commun Signal. 2020 Jan 27;18(1):14. doi: 10.1186/s12964-019-0496-2. Cell Commun Signal. 2020. PMID: 31987048 Free PMC article. Review.
The triple complex of CSDE1, a regulator and an RNA reprograms translation in different directions for each transcript. Meanwhile, a number of recent studies have found important roles for CSDE1 in human diseases. This model will help us to understand the role of …
The triple complex of CSDE1, a regulator and an RNA reprograms translation in different directions for each transcript. Meanwhile, a …
CSDE1 promotes miR-451 biogenesis.
Kakumani PK, Ko Y, Ramakrishna S, Christopher G, Dodgson M, Shrinet J, Harvey LM, Shin C, Simard MJ. Kakumani PK, et al. Nucleic Acids Res. 2023 Sep 22;51(17):9385-9396. doi: 10.1093/nar/gkad619. Nucleic Acids Res. 2023. PMID: 37493604 Free PMC article.
CSDE1 binds miR-451 and regulates AGO2 processing of pre-miR-451 through its N-terminal domains. ...Together, our results demonstrate that CSDE1 promotes biogenesis of miR-451 in erythroid progenitors....
CSDE1 binds miR-451 and regulates AGO2 processing of pre-miR-451 through its N-terminal domains. ...Together, our results demonstrate …
Epigenetic modification of CSDE1 locus dictates immune recognition of nascent tumorigenic cells.
Lv J, Zhou Y, Zhou N, Wang Z, Chen J, Chen H, Wang D, Zhou L, Wei K, Zhang H, Tang K, Ma J, Liu Y, Wan Y, Zhang Y, Zhang H, Huang B. Lv J, et al. Sci Transl Med. 2023 Feb;15(681):eabq6024. doi: 10.1126/scitranslmed.abq6024. Epub 2023 Feb 1. Sci Transl Med. 2023. PMID: 36724242
Subsequent investigation identified that the RNA binding protein cold shock domain-containing protein E1 (CSDE1) can promote STAT1 dephosphorylation by stabilizing T cell protein tyrosine phosphatase (TCPTP). ...Thus, owing to the differential epigenetic modification and s …
Subsequent investigation identified that the RNA binding protein cold shock domain-containing protein E1 (CSDE1) can promote STAT1 de …
CSDE1 regulates LDL receptor levels.
Lim GB. Lim GB. Nat Rev Cardiol. 2022 Dec;19(12):782. doi: 10.1038/s41569-022-00795-6. Nat Rev Cardiol. 2022. PMID: 36180591 No abstract available.
CSDE1 attenuates microRNA-mediated silencing of PMEPA1 in melanoma.
Kakumani PK, Guitart T, Houle F, Harvey LM, Goyer B, Germain L, Gebauer F, Simard MJ. Kakumani PK, et al. Oncogene. 2021 May;40(18):3231-3244. doi: 10.1038/s41388-021-01767-9. Epub 2021 Apr 8. Oncogene. 2021. PMID: 33833398
We find an association of CSDE1 with AGO2, the essential component of miRISC, which is facilitated by target mRNAs and depends on the first cold shock domain of CSDE1. Both CSDE1 and AGO2 bind to 3' UTR of PMEPA1. CSDE1 counters AGO2 binding, leading t …
We find an association of CSDE1 with AGO2, the essential component of miRISC, which is facilitated by target mRNAs and depends on the …
A Csde1-Strap complex regulates plasma cell differentiation by coupling mRNA translation and decay.
Chen P, Lin L, Lin X, Liao K, Qiang J, Wang Z, Wu J, Li Y, Yang L, Yao N, Song H, Hong Y, Liu WH, Zhang Y, Chang X, Du D, Xiao C. Chen P, et al. Nat Commun. 2025 Mar 25;16(1):2906. doi: 10.1038/s41467-025-58212-8. Nat Commun. 2025. PMID: 40133358 Free PMC article.
Here we find by RNA interactome capture-coupled CRISPR/Cas9 functional screening that the Csde1-Strap complex plays an important role in plasma cell differentiation. Mechanistically, the Csde1-Strap complex establishes the expression kinetics of Bach2, a key regulat …
Here we find by RNA interactome capture-coupled CRISPR/Cas9 functional screening that the Csde1-Strap complex plays an important role …
Csde1 Mediates Neurogenesis via Post-transcriptional Regulation of the Cell Cycle.
Jia X, Xie W, Du B, He M, Chen J, Chen M, Zhang G, Wang K, Xu W, Liao Y, Tan S, Lyu Y, Yu B, Zheng Z, Sun X, Liao Y, Hu Z, Yuan L, Tan J, Xia K, Guo H. Jia X, et al. Neurosci Bull. 2025 Nov;41(11):1977-1990. doi: 10.1007/s12264-025-01426-z. Epub 2025 Jun 24. Neurosci Bull. 2025. PMID: 40555862
Loss-of-function variants in CSDE1 have been strongly linked to neuropsychiatric disorders, yet the precise role of CSDE1 in neurogenesis remains elusive. ...Collectively, this study elucidates Csde1 as a novel regulator of Cdk6, sheds new light on its critic …
Loss-of-function variants in CSDE1 have been strongly linked to neuropsychiatric disorders, yet the precise role of CSDE1 in n …
CSDE1 Intracellular Distribution as a Biomarker of Melanoma Prognosis.
Indacochea A, Guitart T, Boada A, Peg V, Quer A, Laayouni H, Condal L, Espinosa P, Manzano JL, Gebauer F. Indacochea A, et al. Int J Mol Sci. 2024 Feb 15;25(4):2319. doi: 10.3390/ijms25042319. Int J Mol Sci. 2024. PMID: 38396995 Free PMC article.
Here, we design a monoclonal antibody useful for IHC in the clinical setting and use it to evaluate the prognosis potential of CSDE1 in an exploratory cohort of 149 whole tissue sections including benign nevi and primary tumors and metastasis from melanoma patients. Contra …
Here, we design a monoclonal antibody useful for IHC in the clinical setting and use it to evaluate the prognosis potential of CSDE1 …
CSDE1 controls gene expression through the miRNA-mediated decay machinery.
Kakumani PK, Harvey LM, Houle F, Guitart T, Gebauer F, Simard MJ. Kakumani PK, et al. Life Sci Alliance. 2020 Mar 11;3(4):e201900632. doi: 10.26508/lsa.201900632. Print 2020 Apr. Life Sci Alliance. 2020. PMID: 32161113 Free PMC article.
We show that CSDE1 interacts with LSM14A, a constituent of P-body assembly and further associates to the DCP1-DCP2 decapping complex, suggesting that CSDE1 could promote the decay of miRNA-induced silencing complex-targeted mRNAs. Together, our findings uncover a hi …
We show that CSDE1 interacts with LSM14A, a constituent of P-body assembly and further associates to the DCP1-DCP2 decapping complex, …
Coordinated post-transcriptional control of oncogene-induced senescence by UNR/CSDE1.
Avolio R, Inglés-Ferrándiz M, Ciocia A, Coll O, Bonnin S, Guitart T, Ribó A, Gebauer F. Avolio R, et al. Cell Rep. 2022 Jan 11;38(2):110211. doi: 10.1016/j.celrep.2021.110211. Cell Rep. 2022. PMID: 35021076 Free article.
Here, we show that the RNA-binding protein UNR/CSDE1 enables OIS in primary mouse keratinocytes. Depletion of CSDE1 leads to senescence bypass, cell immortalization, and tumor formation, indicating that CSDE1 behaves as a tumor suppressor. Unbiased high-throu …
Here, we show that the RNA-binding protein UNR/CSDE1 enables OIS in primary mouse keratinocytes. Depletion of CSDE1 leads to s …
129 results