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The following terms were not found in PubMed: Ca2++Insulin, secretion+RINm5F, cells+Tillandsia, usneoides+Type
Page 1
Resistin induces rat insulinoma cell RINm5F apoptosis.
Gao CL, Zhao DY, Qiu J, Zhang CM, Ji CB, Chen XH, Liu F, Guo XR. Gao CL, et al. Mol Biol Rep. 2009 Sep;36(7):1703-8. doi: 10.1007/s11033-008-9371-8. Epub 2008 Oct 7. Mol Biol Rep. 2009. PMID: 18839335
Beta-cell apoptosis induced by adipokines may result in beta-cell dysfunction in type 2 diabetes. Resistin, an adipokine-linked obesity with type 2 diabetes, impairs glucose-stimulated insulin secretion (GSIS) in beta-cells. Presently, the effects of r …
Beta-cell apoptosis induced by adipokines may result in beta-cell dysfunction in type 2 diabetes. Resistin, an adipokine-linke …
Opposite effects of D-glucose and a nonmetabolized analogue of L-leucine on respiration and secretion in insulin-producing tumoral cells (RINm5F).
Sener A, Leclercq-Meyer V, Giroix MH, Malaisse WJ, Hellerström C. Sener A, et al. Diabetes. 1987 Feb;36(2):187-92. doi: 10.2337/diab.36.2.187. Diabetes. 1987. PMID: 3542645
D-Glucose increased the cytosolic NADH/NAD+ ratio (but not the cytosolic NADPH/NADP+ ratio), augmented O2 uptake, raised the ATP/ADP ratio, decreased 86Rb outflow, and stimulated insulin release in tumoral insulin-producing cells of the RINm5F line. L-Leucine and 4-methyl-2 …
D-Glucose increased the cytosolic NADH/NAD+ ratio (but not the cytosolic NADPH/NADP+ ratio), augmented O2 uptake, raised the ATP/ADP ratio, …
Cytokines inhibit proliferation and insulin secretion by clonal rat insulinoma cells (RINm5F) non-synergistically and in a pertussis toxin-insensitive manner.
Sjöholm A. Sjöholm A. Immunol Lett. 1991 Sep;30(1):81-6. doi: 10.1016/0165-2478(91)90093-p. Immunol Lett. 1991. PMID: 1959944
It has been proposed that certain cytokines secreted by islet-infiltrating leukocytes may be involved in the pathogenesis of insulin-dependent diabetes mellitus. Since the cytotoxic actions by the cytokines may reflect interactions with islet cell types other than t …
It has been proposed that certain cytokines secreted by islet-infiltrating leukocytes may be involved in the pathogenesis of insulin-depende …
[Resistin inhibits rat insulinoma cell RINm5F proliferation].
Liu F, Qiu J, Zhang CM, Ji CB, Guo XR. Liu F, et al. Zhongguo Dang Dai Er Ke Za Zhi. 2010 Jan;12(1):43-6. Zhongguo Dang Dai Er Ke Za Zhi. 2010. PMID: 20113634 Free article. Chinese.
OBJECTIVE: Resistin was thought to link the obesity to type 2 diabetes. This study aimed to investigate the effect of resistin on insulinoma cell proliferation. METHODS: pcDNA3.1-resistin was transfected into rat insulinoma cells RINm5F. Cell prolifera …
OBJECTIVE: Resistin was thought to link the obesity to type 2 diabetes. This study aimed to investigate the effect of resistin …
Nicorandil improves diabetes and rat islet beta-cell damage induced by streptozotocin in vivo and in vitro.
Kasono K, Yasu T, Kakehashi A, Kinoshita N, Tamemoto H, Namai K, Ohno R, Ueba H, Kuroki M, Ishikawa S, Kawakami M. Kasono K, et al. Eur J Endocrinol. 2004 Aug;151(2):277-85. doi: 10.1530/eje.0.1510277. Eur J Endocrinol. 2004. PMID: 15296485
We examined the effects of nicorandil on streptozotocin (STZ)-induced islet beta-cell damage both in vivo and in vitro. DESIGN AND METHODS: STZ-induced diabetic Brown Norway rats (STZ-DM) were fed with nicorandil-containing chow from day 2 (STZ-DM-N48), 3 (STZ-DM-N7 …
We examined the effects of nicorandil on streptozotocin (STZ)-induced islet beta-cell damage both in vivo and in vitro. DESIGN AND METHODS: …
Anchoring of protein kinase A facilitates hormone-mediated insulin secretion.
Lester LB, Langeberg LK, Scott JD. Lester LB, et al. Proc Natl Acad Sci U S A. 1997 Dec 23;94(26):14942-7. doi: 10.1073/pnas.94.26.14942. Proc Natl Acad Sci U S A. 1997. PMID: 9405718 Free PMC article.
Impaired insulin secretion is a characteristic of non-insulin-dependent diabetes mellitus (NIDDM). One possible therapeutic agent for NIDDM is the insulinotropic hormone glucagon-like peptide 1 (GLP-1). ...Disruption of PKA anchoring by the introduction of anchoring …
Impaired insulin secretion is a characteristic of non-insulin-dependent diabetes mellitus (NIDDM). One possible therapeutic ag …
Increased cytokine-induced cytotoxicity of pancreatic islet cells from transgenic mice expressing the Src-like tyrosine kinase GTK.
Annerén C, Welsh M. Annerén C, et al. Mol Med. 2001 May;7(5):301-10. Mol Med. 2001. PMID: 11474576 Free PMC article.
BACKGROUND: The loss of beta cells in type 1 diabetes may involve protein kinases because they control cell growth, differentiation, and survival. ...Extracellular signal-regulated kinase (ERK) 1/2, p38 mitogen-activated protein kinase (MAPK), c-Jun NH2-terminal kin …
BACKGROUND: The loss of beta cells in type 1 diabetes may involve protein kinases because they control cell growth, differentiation, …
Transcriptional regulation of cyclooxygenase-2 gene in pancreatic beta-cells.
Yang F, Bleich D. Yang F, et al. J Biol Chem. 2004 Aug 20;279(34):35403-11. doi: 10.1074/jbc.M404055200. Epub 2004 Jun 21. J Biol Chem. 2004. PMID: 15213229 Free article.
Prostaglandin E(2) (PGE(2)) has been shown to negatively affect pancreatic beta-cell function, and its inducible synthesis is mediated in part by cycloxygenase-2 (COX-2). Regulation of basal and inducible COX-2 gene expression in pancreatic beta …
Prostaglandin E(2) (PGE(2)) has been shown to negatively affect pancreatic beta-cell function, and its inducible synthesis is …
Protective Mechanism of KIOM-4 in Streptozotocin-Induced Pancreatic β-Cells Damage Is Involved in the Inhibition of Endoplasmic Reticulum Stress.
Zhang R, Kim JS, Kang KA, Piao MJ, Kim KC, Hyun JW. Zhang R, et al. Evid Based Complement Alternat Med. 2011;2011:231938. doi: 10.1155/2011/231938. Epub 2010 Sep 16. Evid Based Complement Alternat Med. 2011. PMID: 20924496 Free PMC article.
Endoplasmic reticulum stress-mediated apoptosis plays an important role in the destruction of pancreatic beta-cells and contributes to the development of type 1 diabetes. The present study examined the effect of KIOM-4, a mixture of four plant extracts, on streptozotocin- …
Endoplasmic reticulum stress-mediated apoptosis plays an important role in the destruction of pancreatic beta-cells and contributes to the d …
Influence of cytokines on Dmt1 iron transporter and ferritin expression in insulin-secreting cells.
Lortz S, Schröter S, Stückemann V, Mehmeti I, Lenzen S. Lortz S, et al. J Mol Endocrinol. 2014 Jun;52(3):301-10. doi: 10.1530/JME-13-0261. J Mol Endocrinol. 2014. PMID: 24850829
Free intracellular ferrous iron (Fe(2+)) is essential for the generation of the extremely toxic hydroxyl radicals, which contribute to beta-cell destruction by cytokines. ...The Dmt1 isoforms (1A/1B and +IRE/-IRE) and the total Dmt1 expression in insulin-producing cells …
Free intracellular ferrous iron (Fe(2+)) is essential for the generation of the extremely toxic hydroxyl radicals, which contribute t …
18 results