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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1993 1
1994 1
1995 1
1996 2
1997 2
1998 6
1999 9
2000 5
2001 21
2002 20
2003 23
2004 29
2005 28
2006 44
2007 59
2008 67
2009 67
2010 126
2011 126
2012 154
2013 222
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3,477 results

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Page 1
Stabilization of E-cadherin adhesions by COX-2/GSK3β signaling is a targetable pathway in metastatic breast cancer.
Balamurugan K, Poria DK, Sehareen SW, Krishnamurthy S, Tang W, McKennett L, Padmanaban V, Czarra K, Ewald AJ, Ueno NT, Ambs S, Sharan S, Sterneck E. Balamurugan K, et al. JCI Insight. 2023 Mar 22;8(6):e156057. doi: 10.1172/jci.insight.156057. JCI Insight. 2023. PMID: 36757813 Free PMC article.
Metastatic progression of epithelial cancers can be associated with epithelial-mesenchymal transition (EMT) including transcriptional inhibition of E-cadherin (CDH1) expression. Recently, EM plasticity (EMP) and E-cadherin-mediated, cluster-based metastasis and treatment r …
Metastatic progression of epithelial cancers can be associated with epithelial-mesenchymal transition (EMT) including transcriptional inhibi …
Cadherin-1 and cadherin-3 cooperation determines the aggressiveness of pancreatic ductal adenocarcinoma.
Siret C, Dobric A, Martirosyan A, Terciolo C, Germain S, Bonier R, Dirami T, Dusetti N, Tomasini R, Rubis M, Garcia S, Iovanna J, Lombardo D, Rigot V, André F. Siret C, et al. Br J Cancer. 2018 Feb 20;118(4):546-557. doi: 10.1038/bjc.2017.411. Epub 2017 Nov 21. Br J Cancer. 2018. PMID: 29161242 Free PMC article.
We have generated pancreatic cancer cell lines expressing both cadherin-1 and cadherin-3 or only one of these cadherins. Functional implications of such genetic alterations were analysed both in vitro and in vivo. ...In vitro assays showed that cadherins …
We have generated pancreatic cancer cell lines expressing both cadherin-1 and cadherin-3 or only one of these cadherins …
Global distribution of prophylactic total gastrectomy in E-cadherin (CDH1) mutations.
Corso G, Magnoni F, Nicastro V, Bagnardi V, Trovato CM, Veronesi P. Corso G, et al. Semin Oncol. 2022 Apr;49(2):130-135. doi: 10.1053/j.seminoncol.2022.03.001. Epub 2022 Mar 18. Semin Oncol. 2022. PMID: 35393124 Review.
Individuals with germline E-cadherin (CDH1) mutations are at high risk of developing diffuse gastric cancer (GC) and prophylactic total gastrectomy (PTG) represents the only life-saving treatment. ...PTG remains the best treatment for individuals harboring germline CDH1 …
Individuals with germline E-cadherin (CDH1) mutations are at high risk of developing diffuse gastric cancer (GC) and prophylactic tot …
Low expression of E-Cadherin and CDH1 variants associated with diffuse gastric cancer.
García-Ruvalcaba A, Vázquez-Ibarra KC, Magaña-Torres MT, Rizo de-la-Torre LDC, Meléndez-Aranda L, López-Armas G, Cruz-Ramos JA, Peregrina-Sandoval J, Espinoza-Jiménez E, Rosales-Gradilla ME, Sánchez-López JY. García-Ruvalcaba A, et al. Rev Invest Clin. 2023 Feb 20;75(1):037-044. doi: 10.24875/RIC.22000257. Rev Invest Clin. 2023. PMID: 36652613 Free article.
More than 50% of patients with DGC present somatic variants in CDH1 gene. OBJECTIVES: The objectives of this study were to study E-cadherin expression and identify variants in the CDH1 gene in gastric tumors of patients with DGC. ...RESULTS: We found that 56% of DGC …
More than 50% of patients with DGC present somatic variants in CDH1 gene. OBJECTIVES: The objectives of this study were to study E-ca …
Gene of the month: E-cadherin (CDH1).
Gall TM, Frampton AE. Gall TM, et al. J Clin Pathol. 2013 Nov;66(11):928-32. doi: 10.1136/jclinpath-2013-201768. Epub 2013 Aug 12. J Clin Pathol. 2013. PMID: 23940132 Review. No abstract available.
CDH1/E-cadherin and solid tumors. An updated gene-disease association analysis using bioinformatics tools.
Abascal MF, Besso MJ, Rosso M, Mencucci MV, Aparicio E, Szapiro G, Furlong LI, Vazquez-Levin MH. Abascal MF, et al. Comput Biol Chem. 2016 Feb;60:9-20. doi: 10.1016/j.compbiolchem.2015.10.002. Epub 2015 Nov 7. Comput Biol Chem. 2016. PMID: 26674224
A systematic study was carried out to gather and summarize current knowledge on CDH1/E-cadherin and ST using bioinformatics resources. The DisGeNET database was exploited to survey CDH1-associated diseases. ...Using CDH1 as query term, 26 disease concepts wer …
A systematic study was carried out to gather and summarize current knowledge on CDH1/E-cadherin and ST using bioinformatics resources …
Zinc Inhibits Cadherin 1 Expression Induced by 1alpha,25-Dihydroxyvitamin D(3) in Colon Cancer Cells.
Ishizawa M, Hirayu A, Makishima M. Ishizawa M, et al. Anticancer Res. 2021 Nov;41(11):5453-5459. doi: 10.21873/anticanres.15357. Anticancer Res. 2021. PMID: 34732414
MATERIALS AND METHODS: Colon cancer SW480 and HCT116 cells were treated with zinc chloride (ZnCl(2)) with/without 1,25(OH)(2)D(3) Expression of zinc-inducible genes [metallothionein 1A (MT1A) and MT2A] and VDR target genes [cytochrome P450 family 24 subfamily A member 1 (CYP24A1) …
MATERIALS AND METHODS: Colon cancer SW480 and HCT116 cells were treated with zinc chloride (ZnCl(2)) with/without 1,25(OH)(2)D(3) Expression …
E-cadherin (CDH1) gene -160C/A polymorphism and the risk of colorectal cancer: A meta-analysis involving 17,291 subjects.
Ye CC, Wang J. Ye CC, et al. J Gene Med. 2021 Oct;23(10):e3370. doi: 10.1002/jgm.3370. Epub 2021 Jul 2. J Gene Med. 2021. PMID: 34097324 Review.
BACKGROUND: The E-cadherin (CDH1) polymorphism has been implicated in the susceptibility to colorectal cancer (CRC). ...Overall, no significant associations between the CDH1 -160C/A polymorphism and CRC risk were detected. In subgroup analysis by ethnicity, source o …
BACKGROUND: The E-cadherin (CDH1) polymorphism has been implicated in the susceptibility to colorectal cancer (CRC). ...Overall, no s …
[Prophylactic gastrectomy].
Côme P, Rochefort P, De Crignis L, Dupré A. Côme P, et al. Bull Cancer. 2025 Mar;112(3):259-262. doi: 10.1016/j.bulcan.2024.04.003. Epub 2024 May 15. Bull Cancer. 2025. PMID: 38755036 Review. French.
One to 3% of gastric cancers are secondary to genetic predisposition, notably hereditary diffuse gastric cancers (HDGC) caused by CDH1 gene mutations. According to French recommendations, in case of CDH1 gene mutation, a prophylactic total gastrectomy should be perf …
One to 3% of gastric cancers are secondary to genetic predisposition, notably hereditary diffuse gastric cancers (HDGC) caused by CDH1 …
3,477 results