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Identification of potent phenyl imidazoles as opioid receptor agonists.
Breslin HJ, Cai C, Miskowski TA, Coutinho SV, Zhang SP, Hornby P, He W. Breslin HJ, et al. Among authors: cai c. Bioorg Med Chem Lett. 2006 May 1;16(9):2505-8. doi: 10.1016/j.bmcl.2006.01.082. Epub 2006 Feb 17. Bioorg Med Chem Lett. 2006. PMID: 16483774
Design, synthesis and SAR of a novel series of heterocyclic phenylpropanoic acids as GPR120 agonists.
Zhang X, Cai C, Winters M, Wells M, Wall M, Lanter J, Sui Z, Ma J, Novack A, Nashashibi I, Wang Y, Yan W, Suckow A, Hua H, Bell A, Haug P, Clapper W, Jenkinson C, Gunnet J, Leonard J, Murray WV. Zhang X, et al. Among authors: cai c. Bioorg Med Chem Lett. 2017 Aug 1;27(15):3272-3278. doi: 10.1016/j.bmcl.2017.06.028. Epub 2017 Jun 12. Bioorg Med Chem Lett. 2017. PMID: 28642104
Discovery of an Isothiazole-Based Phenylpropanoic Acid GPR120 Agonist as a Development Candidate for Type 2 Diabetes.
Zhang X, Cai C, Sui Z, Macielag M, Wang Y, Yan W, Suckow A, Hua H, Bell A, Haug P, Clapper W, Jenkinson C, Gunnet J, Leonard J, Murray WV. Zhang X, et al. Among authors: cai c. ACS Med Chem Lett. 2017 Jul 27;8(9):947-952. doi: 10.1021/acsmedchemlett.7b00233. eCollection 2017 Sep 14. ACS Med Chem Lett. 2017. PMID: 28947942 Free PMC article.
Diabetogenic effect of a series of tricyclic delta opioid agonists structurally related to cyproheptadine.
Codd EE, Baker J, Brandt MR, Bryant S, Cai C, Carson JR, Chevalier KM, Colburn RW, Coogan TP, Dax SL, Decorte B, Kemmerer M, Legrand EK, Lenhard JM, Leone AM, Lin L, Mabus JR, McDonnell ME, McMillian MK, McNally JJ, Stone DJ Jr, Wang CY, Zhang SP, Flores CM. Codd EE, et al. Among authors: cai c. Toxicol Sci. 2010 Oct;117(2):493-504. doi: 10.1093/toxsci/kfq200. Epub 2010 Jul 8. Toxicol Sci. 2010. PMID: 20616206
5,027 results