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Modulating Antibody-Drug Conjugate Payload Metabolism by Conjugation Site and Linker Modification.
Su D, Kozak KR, Sadowsky J, Yu SF, Fourie-O'Donohue A, Nelson C, Vandlen R, Ohri R, Liu L, Ng C, He J, Davis H, Lau J, Del Rosario G, Cosino E, Cruz-Chuh JD, Ma Y, Zhang D, Darwish M, Cai W, Chen C, Zhou H, Lu J, Liu Y, Kaur S, Xu K, Pillow TH. Su D, et al. Among authors: cai w. Bioconjug Chem. 2018 Apr 18;29(4):1155-1167. doi: 10.1021/acs.bioconjchem.7b00785. Epub 2018 Mar 13. Bioconjug Chem. 2018. PMID: 29481745
Stabilizing a Tubulysin Antibody-Drug Conjugate To Enable Activity Against Multidrug-Resistant Tumors.
Staben LR, Yu SF, Chen J, Yan G, Xu Z, Del Rosario G, Lau JT, Liu L, Guo J, Zheng B, Cruz-Chuh JD, Lee BC, Ohri R, Cai W, Zhou H, Kozak KR, Xu K, Lewis Phillips GD, Lu J, Wai J, Polson AG, Pillow TH. Staben LR, et al. Among authors: cai w. ACS Med Chem Lett. 2017 Sep 5;8(10):1037-1041. doi: 10.1021/acsmedchemlett.7b00243. eCollection 2017 Oct 12. ACS Med Chem Lett. 2017. PMID: 29057047 Free PMC article.
Guilu Erxian glue reduces endoplasmic reticulum stress-mediated apoptosis and restores the balance of extracellular matrix synthesis and degradation in chondrocytes by inhibiting the ATF6/GRP78/CHOP signaling pathway.
Geng Q, Wu W, Yang M, Gu F, Cai W, Qin Y, Wei L, Wang H, Li N. Geng Q, et al. Among authors: cai w. Heliyon. 2024 Oct 31;10(24):e39987. doi: 10.1016/j.heliyon.2024.e39987. eCollection 2024 Dec 30. Heliyon. 2024. PMID: 39759286 Free PMC article.
TRIOL attenuates intracerebral hemorrhage injury by bidirectionally modulating microglia- and neuron-mediated hematoma clearance.
Wei C, Chen C, Li S, Ding Y, Zhou Y, Mai F, Hong S, Wu J, Yang Y, Zhu Z, Xue D, Ning X, Sheng L, Lu B, Cai W, Yuan M, Liang H, Lin S, Yan G, Chen Y, Huang Y, Hu C, Yin W. Wei C, et al. Among authors: cai w. Redox Biol. 2024 Dec 31;80:103487. doi: 10.1016/j.redox.2024.103487. Online ahead of print. Redox Biol. 2024. PMID: 39756315
8,402 results