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Altered trafficking and stability of polycystins underlie polycystic kidney disease.
Cai Y, Fedeles SV, Dong K, Anyatonwu G, Onoe T, Mitobe M, Gao JD, Okuhara D, Tian X, Gallagher AR, Tang Z, Xie X, Lalioti MD, Lee AH, Ehrlich BE, Somlo S. Cai Y, et al. J Clin Invest. 2014 Dec;124(12):5129-44. doi: 10.1172/JCI67273. Epub 2014 Nov 3. J Clin Invest. 2014. PMID: 25365220 Free PMC article.
Cloning and characterization of the murine pkd2 promoter.
Park JH, Li L, Cai Y, Hayashi T, Dong F, Maeda Y, Rubin C, Somlo S, Wu G. Park JH, et al. Among authors: cai y. Genomics. 2000 Jun 15;66(3):305-12. doi: 10.1006/geno.2000.6197. Genomics. 2000. PMID: 10873385
Cardiac defects and renal failure in mice with targeted mutations in Pkd2.
Wu G, Markowitz GS, Li L, D'Agati VD, Factor SM, Geng L, Tibara S, Tuchman J, Cai Y, Park JH, van Adelsberg J, Hou H Jr, Kucherlapati R, Edelmann W, Somlo S. Wu G, et al. Among authors: cai y. Nat Genet. 2000 Jan;24(1):75-8. doi: 10.1038/71724. Nat Genet. 2000. PMID: 10615132
Aberrant splicing in the PKD2 gene as a cause of polycystic kidney disease.
Reynolds DM, Hayashi T, Cai Y, Veldhuisen B, Watnick TJ, Lens XM, Mochizuki T, Qian F, Maeda Y, Li L, Fossdal R, Coto E, Wu G, Breuning MH, Germino GG, Peters DJ, Somlo S. Reynolds DM, et al. Among authors: cai y. J Am Soc Nephrol. 1999 Nov;10(11):2342-51. doi: 10.1681/ASN.V10112342. J Am Soc Nephrol. 1999. PMID: 10541293
Polycystin-2 expression is developmentally regulated.
Markowitz GS, Cai Y, Li L, Wu G, Ward LC, Somlo S, D'Agati VD. Markowitz GS, et al. Among authors: cai y. Am J Physiol. 1999 Jul;277(1):F17-25. doi: 10.1152/ajprenal.1999.277.1.F17. Am J Physiol. 1999. PMID: 10409293
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