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213 results
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T-type calcium channels in burst-firing, network synchrony, and epilepsy.
Cain SM, Snutch TP. Cain SM, et al. Biochim Biophys Acta. 2013 Jul;1828(7):1572-8. doi: 10.1016/j.bbamem.2012.07.028. Epub 2012 Aug 2. Biochim Biophys Acta. 2013. PMID: 22885138 Review.
A Cav3.2 T-type calcium channel point mutation has splice-variant-specific effects on function and segregates with seizure expression in a polygenic rat model of absence epilepsy.
Powell KL, Cain SM, Ng C, Sirdesai S, David LS, Kyi M, Garcia E, Tyson JR, Reid CA, Bahlo M, Foote SJ, Snutch TP, O'Brien TJ. Powell KL, et al. Among authors: cain sm. J Neurosci. 2009 Jan 14;29(2):371-80. doi: 10.1523/JNEUROSCI.5295-08.2009. J Neurosci. 2009. PMID: 19144837 Free PMC article.
Splice-variant changes of the Ca(V)3.2 T-type calcium channel mediate voltage-dependent facilitation and associate with cardiac hypertrophy and development.
David LS, Garcia E, Cain SM, Thau E, Tyson JR, Snutch TP. David LS, et al. Among authors: cain sm. Channels (Austin). 2010 Sep-Oct;4(5):375-89. doi: 10.4161/chan.4.5.12874. Epub 2010 Sep 1. Channels (Austin). 2010. PMID: 20699644 Free PMC article.
Contributions of T-type calcium channel isoforms to neuronal firing.
Cain SM, Snutch TP. Cain SM, et al. Channels (Austin). 2010 Nov-Dec;4(6):475-82. doi: 10.4161/chan.4.6.14106. Channels (Austin). 2010. PMID: 21139420 Free PMC article. Review.
Voltage-gated calcium channels and disease.
Cain SM, Snutch TP. Cain SM, et al. Biofactors. 2011 May-Jun;37(3):197-205. doi: 10.1002/biof.158. Biofactors. 2011. PMID: 21698699 Review.
T-type calcium channel blockers that attenuate thalamic burst firing and suppress absence seizures.
Tringham E, Powell KL, Cain SM, Kuplast K, Mezeyova J, Weerapura M, Eduljee C, Jiang X, Smith P, Morrison JL, Jones NC, Braine E, Rind G, Fee-Maki M, Parker D, Pajouhesh H, Parmar M, O'Brien TJ, Snutch TP. Tringham E, et al. Among authors: cain sm. Sci Transl Med. 2012 Feb 15;4(121):121ra19. doi: 10.1126/scitranslmed.3003120. Sci Transl Med. 2012. PMID: 22344687
Low threshold T-type calcium channels as targets for novel epilepsy treatments.
Powell KL, Cain SM, Snutch TP, O'Brien TJ. Powell KL, et al. Among authors: cain sm. Br J Clin Pharmacol. 2014 May;77(5):729-39. doi: 10.1111/bcp.12205. Br J Clin Pharmacol. 2014. PMID: 23834404 Free PMC article. Review.
Thalamocortical neurons display suppressed burst-firing due to an enhanced Ih current in a genetic model of absence epilepsy.
Cain SM, Tyson JR, Jones KL, Snutch TP. Cain SM, et al. Pflugers Arch. 2015 Jun;467(6):1367-82. doi: 10.1007/s00424-014-1549-4. Epub 2014 Jun 24. Pflugers Arch. 2015. PMID: 24953239 Free PMC article.
Epigallocatechin-3-gallate elicits Ca2+ spike in MCF-7 breast cancer cells: essential role of Cav3.2 channels.
Ranzato E, Magnelli V, Martinotti S, Waheed Z, Cain SM, Snutch TP, Marchetti C, Burlando B. Ranzato E, et al. Among authors: cain sm. Cell Calcium. 2014 Oct;56(4):285-95. doi: 10.1016/j.ceca.2014.09.002. Epub 2014 Sep 15. Cell Calcium. 2014. PMID: 25260713
The cellular mechanisms of neuronal swelling underlying cytotoxic edema.
Rungta RL, Choi HB, Tyson JR, Malik A, Dissing-Olesen L, Lin PJC, Cain SM, Cullis PR, Snutch TP, MacVicar BA. Rungta RL, et al. Among authors: cain sm. Cell. 2015 Apr 23;161(3):610-621. doi: 10.1016/j.cell.2015.03.029. Cell. 2015. PMID: 25910210
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