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Control of tumor bioenergetics and survival stress signaling by mitochondrial HSP90s.
Chae YC, Caino MC, Lisanti S, Ghosh JC, Dohi T, Danial NN, Villanueva J, Ferrero S, Vaira V, Santambrogio L, Bosari S, Languino LR, Herlyn M, Altieri DC. Chae YC, et al. Among authors: Caino MC. Cancer Cell. 2012 Sep 11;22(3):331-44. doi: 10.1016/j.ccr.2012.07.015. Cancer Cell. 2012. PMID: 22975376 Free PMC article.
Metabolic stress regulates cytoskeletal dynamics and metastasis of cancer cells.
Caino MC, Chae YC, Vaira V, Ferrero S, Nosotti M, Martin NM, Weeraratna A, O'Connell M, Jernigan D, Fatatis A, Languino LR, Bosari S, Altieri DC. Caino MC, et al. J Clin Invest. 2013 Jul;123(7):2907-20. doi: 10.1172/JCI67841. Epub 2013 Jun 10. J Clin Invest. 2013. PMID: 23921130 Free PMC article.
Adaptive mitochondrial reprogramming and resistance to PI3K therapy.
Ghosh JC, Siegelin MD, Vaira V, Faversani A, Tavecchio M, Chae YC, Lisanti S, Rampini P, Giroda M, Caino MC, Seo JH, Kossenkov AV, Michalek RD, Schultz DC, Bosari S, Languino LR, Altieri DC. Ghosh JC, et al. Among authors: Caino MC. J Natl Cancer Inst. 2015 Feb 3;107(3):dju502. doi: 10.1093/jnci/dju502. Print 2015 Mar. J Natl Cancer Inst. 2015. PMID: 25650317 Free PMC article.
PI3K therapy reprograms mitochondrial trafficking to fuel tumor cell invasion.
Caino MC, Ghosh JC, Chae YC, Vaira V, Rivadeneira DB, Faversani A, Rampini P, Kossenkov AV, Aird KM, Zhang R, Webster MR, Weeraratna AT, Bosari S, Languino LR, Altieri DC. Caino MC, et al. Proc Natl Acad Sci U S A. 2015 Jul 14;112(28):8638-43. doi: 10.1073/pnas.1500722112. Epub 2015 Jun 29. Proc Natl Acad Sci U S A. 2015. PMID: 26124089 Free PMC article.
Disabling mitochondrial reprogramming in cancer.
Caino MC, Altieri DC. Caino MC, et al. Pharmacol Res. 2015 Dec;102:42-5. doi: 10.1016/j.phrs.2015.08.022. Epub 2015 Sep 10. Pharmacol Res. 2015. PMID: 26365877 Free PMC article.
The Mitochondrial Unfoldase-Peptidase Complex ClpXP Controls Bioenergetics Stress and Metastasis.
Seo JH, Rivadeneira DB, Caino MC, Chae YC, Speicher DW, Tang HY, Vaira V, Bosari S, Palleschi A, Rampini P, Kossenkov AV, Languino LR, Altieri DC. Seo JH, et al. Among authors: Caino MC. PLoS Biol. 2016 Jul 7;14(7):e1002507. doi: 10.1371/journal.pbio.1002507. eCollection 2016 Jul. PLoS Biol. 2016. PMID: 27389535 Free PMC article.
Mitochondrial Akt Regulation of Hypoxic Tumor Reprogramming.
Chae YC, Vaira V, Caino MC, Tang HY, Seo JH, Kossenkov AV, Ottobrini L, Martelli C, Lucignani G, Bertolini I, Locatelli M, Bryant KG, Ghosh JC, Lisanti S, Ku B, Bosari S, Languino LR, Speicher DW, Altieri DC. Chae YC, et al. Among authors: Caino MC. Cancer Cell. 2016 Aug 8;30(2):257-272. doi: 10.1016/j.ccell.2016.07.004. Cancer Cell. 2016. PMID: 27505672 Free PMC article.
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