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206 results

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Page 1
Clonal expansion and epigenetic reprogramming following deletion or amplification of mutant IDH1.
Mazor T, Chesnelong C, Pankov A, Jalbert LE, Hong C, Hayes J, Smirnov IV, Marshall R, Souza CF, Shen Y, Viswanath P, Noushmehr H, Ronen SM, Jones SJM, Marra MA, Cairncross JG, Perry A, Nelson SJ, Chang SM, Bollen AW, Molinaro AM, Bengtsson H, Olshen AB, Weiss S, Phillips JJ, Luchman HA, Costello JF. Mazor T, et al. Among authors: cairncross jg. Proc Natl Acad Sci U S A. 2017 Oct 3;114(40):10743-10748. doi: 10.1073/pnas.1708914114. Epub 2017 Sep 15. Proc Natl Acad Sci U S A. 2017. PMID: 28916733 Free PMC article.
An in vivo patient-derived model of endogenous IDH1-mutant glioma.
Luchman HA, Stechishin OD, Dang NH, Blough MD, Chesnelong C, Kelly JJ, Nguyen SA, Chan JA, Weljie AM, Cairncross JG, Weiss S. Luchman HA, et al. Among authors: cairncross jg. Neuro Oncol. 2012 Feb;14(2):184-91. doi: 10.1093/neuonc/nor207. Epub 2011 Dec 13. Neuro Oncol. 2012. PMID: 22166263 Free PMC article.
Lactate dehydrogenase A silencing in IDH mutant gliomas.
Chesnelong C, Chaumeil MM, Blough MD, Al-Najjar M, Stechishin OD, Chan JA, Pieper RO, Ronen SM, Weiss S, Luchman HA, Cairncross JG. Chesnelong C, et al. Among authors: cairncross jg. Neuro Oncol. 2014 May;16(5):686-95. doi: 10.1093/neuonc/not243. Epub 2013 Dec 22. Neuro Oncol. 2014. PMID: 24366912 Free PMC article.
IDH1 Mutation Induces Reprogramming of Pyruvate Metabolism.
Izquierdo-Garcia JL, Viswanath P, Eriksson P, Cai L, Radoul M, Chaumeil MM, Blough M, Luchman HA, Weiss S, Cairncross JG, Phillips JJ, Pieper RO, Ronen SM. Izquierdo-Garcia JL, et al. Among authors: cairncross jg. Cancer Res. 2015 Aug 1;75(15):2999-3009. doi: 10.1158/0008-5472.CAN-15-0840. Epub 2015 Jun 4. Cancer Res. 2015. PMID: 26045167 Free PMC article.
2-Hydroxyglutarate-Mediated Autophagy of the Endoplasmic Reticulum Leads to an Unusual Downregulation of Phospholipid Biosynthesis in Mutant IDH1 Gliomas.
Viswanath P, Radoul M, Izquierdo-Garcia JL, Ong WQ, Luchman HA, Cairncross JG, Huang B, Pieper RO, Phillips JJ, Ronen SM. Viswanath P, et al. Among authors: cairncross jg. Cancer Res. 2018 May 1;78(9):2290-2304. doi: 10.1158/0008-5472.CAN-17-2926. Epub 2018 Jan 22. Cancer Res. 2018. PMID: 29358170 Free PMC article.
Comprehensive genomic profiling of glioblastoma tumors, BTICs, and xenografts reveals stability and adaptation to growth environments.
Shen Y, Grisdale CJ, Islam SA, Bose P, Lever J, Zhao EY, Grinshtein N, Ma Y, Mungall AJ, Moore RA, Lun X, Senger DL, Robbins SM, Wang AY, MacIsaac JL, Kobor MS, Luchman HA, Weiss S, Chan JA, Blough MD, Kaplan DR, Cairncross JG, Marra MA, Jones SJM. Shen Y, et al. Among authors: cairncross jg. Proc Natl Acad Sci U S A. 2019 Sep 17;116(38):19098-19108. doi: 10.1073/pnas.1813495116. Epub 2019 Aug 30. Proc Natl Acad Sci U S A. 2019. PMID: 31471491 Free PMC article.
DNA hypermethylation and 1p Loss silence NHE-1 in oligodendroglioma.
Blough MD, Al-Najjar M, Chesnelong C, Binding CE, Rogers AD, Luchman HA, Kelly JJ, Fliegel L, Morozova O, Yip S, Marra M, Weiss S, Chan JA, Cairncross JG. Blough MD, et al. Among authors: cairncross jg. Ann Neurol. 2012 Jun;71(6):845-9. doi: 10.1002/ana.23610. Ann Neurol. 2012. PMID: 22718548
Concurrent CIC mutations, IDH mutations, and 1p/19q loss distinguish oligodendrogliomas from other cancers.
Yip S, Butterfield YS, Morozova O, Chittaranjan S, Blough MD, An J, Birol I, Chesnelong C, Chiu R, Chuah E, Corbett R, Docking R, Firme M, Hirst M, Jackman S, Karsan A, Li H, Louis DN, Maslova A, Moore R, Moradian A, Mungall KL, Perizzolo M, Qian J, Roldan G, Smith EE, Tamura-Wells J, Thiessen N, Varhol R, Weiss S, Wu W, Young S, Zhao Y, Mungall AJ, Jones SJ, Morin GB, Chan JA, Cairncross JG, Marra MA. Yip S, et al. Among authors: cairncross jg. J Pathol. 2012 Jan;226(1):7-16. doi: 10.1002/path.2995. Epub 2011 Nov 10. J Pathol. 2012. PMID: 22072542 Free PMC article.
206 results