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49 results

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Page 1
Effect of Treating Hyperphosphatemia With Lanthanum Carbonate vs Calcium Carbonate on Cardiovascular Events in Patients With Chronic Kidney Disease Undergoing Hemodialysis: The LANDMARK Randomized Clinical Trial.
Ogata H, Fukagawa M, Hirakata H, Kagimura T, Fukushima M, Akizawa T; LANDMARK Investigators and Committees. Ogata H, et al. JAMA. 2021 May 18;325(19):1946-1954. doi: 10.1001/jama.2021.4807. JAMA. 2021. PMID: 34003226 Free PMC article. Clinical Trial.
OBJECTIVE: To determine whether lanthanum carbonate reduces cardiovascular events compared with calcium carbonate in patients with hyperphosphatemia at risk of vascular calcification undergoing hemodialysis. ...INTERVENTIONS: Patients were randomized to recei …
OBJECTIVE: To determine whether lanthanum carbonate reduces cardiovascular events compared with calcium carbonate in pa …
Nutrition, Vitamin D, and Calcium in Elderly Patients before and after a Hip Fracture and Their Impact on the Musculoskeletal System: A Narrative Review.
Cianferotti L, Bifolco G, Caffarelli C, Mazziotti G, Migliaccio S, Napoli N, Ruggiero C, Cipriani C. Cianferotti L, et al. Nutrients. 2024 Jun 5;16(11):1773. doi: 10.3390/nu16111773. Nutrients. 2024. PMID: 38892706 Free PMC article. Review.
An adequate protein intake improves muscle mass and strength and the intestinal absorption of calcium. Other nutrients with recognized beneficial effects on bone health are calcium, vitamins D, K, and C, potassium, magnesium, folate, and carotenoids. With reference …
An adequate protein intake improves muscle mass and strength and the intestinal absorption of calcium. Other nutrients with recognize …
Calcium Carbonate/Polydopamine Composite Nanoplatform Based on TGF-beta Blockade for Comfortable Cancer Immunotherapy.
Li Y, Wang D, Sun J, Hao Z, Tang L, Sun W, Zhang X, Wang P, Ruiz-Alonso S, Pedraz JL, Kim HW, Ramalingam M, Xie S, Wang R. Li Y, et al. ACS Appl Mater Interfaces. 2024 Jan 24;16(3):3187-3201. doi: 10.1021/acsami.3c16571. Epub 2024 Jan 11. ACS Appl Mater Interfaces. 2024. PMID: 38206677
The results indicate that CaPNM(CUR+Ropi) underwent tumor microenvironment-responsive degradation and realized rapid release of calcium ions, Ropi, and CUR. The excessive intracellular calcium triggered the apoptosis of tumor cells, and the transient pain caused by …
The results indicate that CaPNM(CUR+Ropi) underwent tumor microenvironment-responsive degradation and realized rapid release of calcium …
Relative bioavailability and pharmacokinetic comparison of calcium glucoheptonate with calcium carbonate.
Wiria M, Tran HM, Nguyen PHB, Valencia O, Dutta S, Pouteau E. Wiria M, et al. Pharmacol Res Perspect. 2020 Apr;8(2):e00589. doi: 10.1002/prp2.589. Pharmacol Res Perspect. 2020. PMID: 32302064 Free PMC article. Clinical Trial.
The objective of this study was to compare the relative oral bioavailability of calcium from calcium glucoheptonate, a highly soluble calcium salt containing 8.2% of elemental calcium, to that of calcium carbonate. ...The relative oral bi …
The objective of this study was to compare the relative oral bioavailability of calcium from calcium glucoheptonate, a highly …
Hydroxyapatite Functionalized Calcium Carbonate Composites with Ag Nanoparticles: An Integrated Characterization Study.
Bolli E, Kaciulis S, Mezzi A, Ambrogi V, Nocchetti M, Latterini L, Di Michele A, Padeletti G. Bolli E, et al. Nanomaterials (Basel). 2021 Aug 31;11(9):2263. doi: 10.3390/nano11092263. Nanomaterials (Basel). 2021. PMID: 34578579 Free PMC article.
In the present work, composite materials very promising for biomedical and pharma-ceutical applications were investigated. They are composed of silver nanoparticles (Ag NPs) in a matrix constituted of calcium carbonate functionalized with hydroxyapatite (HA-F …
In the present work, composite materials very promising for biomedical and pharma-ceutical applications were investigated. They are c …
Effect of the Phosphate Binders Sevelamer Carbonate and Calcium Acetate on the Pharmacokinetics of Roxadustat After Concomitant or Time-separated Administration in Healthy Individuals.
Groenendaal-van de Meent D, Kerbusch V, Barroso-Fernandez B, den Adel M, van Dijk J, Golor G, Schaddelee M. Groenendaal-van de Meent D, et al. Clin Ther. 2021 Jun;43(6):1079-1091. doi: 10.1016/j.clinthera.2021.03.025. Epub 2021 May 5. Clin Ther. 2021. PMID: 33962762 Free article. Clinical Trial.
This study in healthy individuals investigated the effect of 2 PBs, sevelamer carbonate and calcium acetate, on the pharmacokinetic properties of a single oral dose of roxadustat administered concomitantly or with a time lag. ...On day 1 of each period, participants …
This study in healthy individuals investigated the effect of 2 PBs, sevelamer carbonate and calcium acetate, on the pharmacoki …
Proteomic analysis of a rare urinary stone composed of calcium carbonate and calcium oxalate dihydrate: a case report.
Kaneko K, Matsuta Y, Moriyama M, Yasuda M, Chishima N, Yamaoka N, Fukuuchi T, Miyazawa K, Suzuki K. Kaneko K, et al. Int J Urol. 2014 Mar;21(3):341-6. doi: 10.1111/iju.12282. Epub 2013 Sep 30. Int J Urol. 2014. PMID: 24118610
X-ray diffraction and infrared analysis confirmed that the stone contained calcium carbonate and calcium oxalate dihydrate. Of the identified 53 proteins, 24 have not been previously reported from calcium oxalate- or calcium phosphate-containing …
X-ray diffraction and infrared analysis confirmed that the stone contained calcium carbonate and calcium oxalate dihydr …
Preclinical Pharmacokinetics, Pharmacodynamics and Safety of Sucroferric Oxyhydroxide.
Cozzolino M, Funk F, Rakov V, Phan O, Teitelbaum I. Cozzolino M, et al. Curr Drug Metab. 2014;15(10):953-65. doi: 10.2174/1389200216666150206124424. Curr Drug Metab. 2014. PMID: 25658128 Free PMC article. Review.
Moreoever, in uraemic rats, sucroferric oxyhydroxide was associated with reduced progression of vascular calcification compared with calcium carbonate. In conclusion, sucroferric oxyhydroxide offers a new option for the treatment of hyperphosphataemia, with a high p …
Moreoever, in uraemic rats, sucroferric oxyhydroxide was associated with reduced progression of vascular calcification compared with calc …
Drug loading into porous calcium carbonate microparticles by solvent evaporation.
Preisig D, Haid D, Varum FJ, Bravo R, Alles R, Huwyler J, Puchkov M. Preisig D, et al. Eur J Pharm Biopharm. 2014 Aug;87(3):548-58. doi: 10.1016/j.ejpb.2014.02.009. Epub 2014 Feb 22. Eur J Pharm Biopharm. 2014. PMID: 24568926
The aim of this study was to evaluate a drug-loading method based on solvent evaporation and crystallization, and to investigate the underlying drug-loading mechanisms. Functionalized calcium carbonate (FCC) microparticles and four drugs with different solubility an …
The aim of this study was to evaluate a drug-loading method based on solvent evaporation and crystallization, and to investigate the underly …
Effect of the Phosphate Binder Sevelamer Carbonate on the Bioavailability of Enarodustat, an Oral Erythropoiesis Stimulating Agent.
Pai SM, Yamada H. Pai SM, et al. Clin Pharmacol Drug Dev. 2024 Jan;13(1):111-116. doi: 10.1002/cpdd.1336. Epub 2023 Nov 17. Clin Pharmacol Drug Dev. 2024. PMID: 37975611
Enarodustat is an orally available hypoxia-inducible factor-prolyl hydroxylase inhibitor which can correct the erythropoietic capacity and improve anemia in chronic kidney disease. Sevelamer carbonate, a non-calcium-based polymeric resin, is one of the commonly pres …
Enarodustat is an orally available hypoxia-inducible factor-prolyl hydroxylase inhibitor which can correct the erythropoietic capacity and i …
49 results