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Catalase, a remarkable enzyme: targeting the oldest antioxidant enzyme to find a new cancer treatment approach.
Glorieux C, Calderon PB. Glorieux C, et al. Among authors: calderon pb. Biol Chem. 2017 Sep 26;398(10):1095-1108. doi: 10.1515/hsz-2017-0131. Biol Chem. 2017. PMID: 28384098 Review.
Catalase expression in MCF-7 breast cancer cells is mainly controlled by PI3K/Akt/mTor signaling pathway.
Glorieux C, Auquier J, Dejeans N, Sid B, Demoulin JB, Bertrand L, Verrax J, Calderon PB. Glorieux C, et al. Among authors: calderon pb. Biochem Pharmacol. 2014 May 15;89(2):217-23. doi: 10.1016/j.bcp.2014.02.025. Epub 2014 Mar 11. Biochem Pharmacol. 2014. PMID: 24630930
Catalase overexpression in mammary cancer cells leads to a less aggressive phenotype and an altered response to chemotherapy.
Glorieux C, Dejeans N, Sid B, Beck R, Calderon PB, Verrax J. Glorieux C, et al. Among authors: calderon pb. Biochem Pharmacol. 2011 Nov 15;82(10):1384-90. doi: 10.1016/j.bcp.2011.06.007. Epub 2011 Jun 13. Biochem Pharmacol. 2011. PMID: 21689642
Evaluation of Potential Mechanisms Controlling the Catalase Expression in Breast Cancer Cells.
Glorieux C, Sandoval JM, Dejeans N, Nonckreman S, Bahloula K, Poirel HA, Calderon PB. Glorieux C, et al. Among authors: calderon pb. Oxid Med Cell Longev. 2018 Jan 28;2018:5351967. doi: 10.1155/2018/5351967. eCollection 2018. Oxid Med Cell Longev. 2018. PMID: 29535798 Free PMC article.
Chromatin remodeling regulates catalase expression during cancer cells adaptation to chronic oxidative stress.
Glorieux C, Sandoval JM, Fattaccioli A, Dejeans N, Garbe JC, Dieu M, Verrax J, Renard P, Huang P, Calderon PB. Glorieux C, et al. Among authors: calderon pb. Free Radic Biol Med. 2016 Oct;99:436-450. doi: 10.1016/j.freeradbiomed.2016.08.031. Epub 2016 Aug 31. Free Radic Biol Med. 2016. PMID: 27591797
Regulation of catalase expression in healthy and cancerous cells.
Glorieux C, Zamocky M, Sandoval JM, Verrax J, Calderon PB. Glorieux C, et al. Among authors: calderon pb. Free Radic Biol Med. 2015 Oct;87:84-97. doi: 10.1016/j.freeradbiomed.2015.06.017. Epub 2015 Jun 25. Free Radic Biol Med. 2015. PMID: 26117330 Review.
Potential therapeutic application of the association of vitamins C and K3 in cancer treatment.
Calderon PB, Cadrobbi J, Marques C, Hong-Ngoc N, Jamison JM, Gilloteaux J, Summers JL, Taper HS. Calderon PB, et al. Curr Med Chem. 2002 Dec;9(24):2271-85. doi: 10.2174/0929867023368674. Curr Med Chem. 2002. PMID: 12470246 Review.
In situ modulation of oxidative stress: a novel and efficient strategy to kill cancer cells.
Verrax J, Pedrosa RC, Beck R, Dejeans N, Taper H, Calderon PB. Verrax J, et al. Among authors: calderon pb. Curr Med Chem. 2009;16(15):1821-30. doi: 10.2174/092986709788186057. Curr Med Chem. 2009. PMID: 19442148 Review.
Redox-active quinones and ascorbate: an innovative cancer therapy that exploits the vulnerability of cancer cells to oxidative stress.
Verrax J, Beck R, Dejeans N, Glorieux C, Sid B, Pedrosa RC, Benites J, Vásquez D, Valderrama JA, Calderon PB. Verrax J, et al. Among authors: calderon pb. Anticancer Agents Med Chem. 2011 Feb;11(2):213-21. doi: 10.2174/187152011795255902. Anticancer Agents Med Chem. 2011. PMID: 21395522 Review.
Molecular chaperone Hsp90 as a target for oxidant-based anticancer therapies.
Beck R, Dejeans N, Glorieux C, Pedrosa RC, Vásquez D, Valderrama JA, Calderon PB, Verrax J. Beck R, et al. Among authors: calderon pb. Curr Med Chem. 2011;18(18):2816-25. doi: 10.2174/092986711796011256. Curr Med Chem. 2011. PMID: 21568884 Review.
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