Abstract
The stereotyped behavior induced by apomorphine in rats was inhibited by oxotremorine and tetrahydroaminoacridine (THA). 5-Hydroxytryptophan (5-HTP) did not change stereotypy scores. These data show influence of cholinergic mechanisms on such behavior. Possible clinical applications are discussed.
Publication types
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Research Support, U.S. Gov't, Non-P.H.S.
MeSH terms
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5-Hydroxytryptophan / pharmacology*
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Acridines / pharmacology*
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Animals
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Apomorphine / pharmacology*
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Behavior / drug effects*
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Humans
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Male
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Oxotremorine / pharmacology*
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Rats
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Stereotyped Behavior / drug effects*
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Tacrine / pharmacology*
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Time Factors
Substances
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Acridines
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Tacrine
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Oxotremorine
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5-Hydroxytryptophan
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Apomorphine