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IL-7 engages multiple mechanisms to overcome chronic viral infection and limit organ pathology.
Pellegrini M, Calzascia T, Toe JG, Preston SP, Lin AE, Elford AR, Shahinian A, Lang PA, Lang KS, Morre M, Assouline B, Lahl K, Sparwasser T, Tedder TF, Paik JH, DePinho RA, Basta S, Ohashi PS, Mak TW. Pellegrini M, et al. Among authors: calzascia t. Cell. 2011 Feb 18;144(4):601-13. doi: 10.1016/j.cell.2011.01.011. Epub 2011 Feb 3. Cell. 2011. PMID: 21295337 Free article.
Loss of the signaling adaptor TRAF1 causes CD8+ T cell dysregulation during human and murine chronic infection.
Wang C, McPherson AJ, Jones RB, Kawamura KS, Lin GH, Lang PA, Ambagala T, Pellegrini M, Calzascia T, Aidarus N, Elford AR, Yue FY, Kremmer E, Kovacs CM, Benko E, Tremblay C, Routy JP, Bernard NF, Ostrowski MA, Ohashi PS, Watts TH. Wang C, et al. Among authors: calzascia t. J Exp Med. 2012 Jan 16;209(1):77-91. doi: 10.1084/jem.20110675. Epub 2011 Dec 19. J Exp Med. 2012. PMID: 22184633 Free PMC article.
CD4 T cells, lymphopenia, and IL-7 in a multistep pathway to autoimmunity.
Calzascia T, Pellegrini M, Lin A, Garza KM, Elford AR, Shahinian A, Ohashi PS, Mak TW. Calzascia T, et al. Proc Natl Acad Sci U S A. 2008 Feb 26;105(8):2999-3004. doi: 10.1073/pnas.0712135105. Epub 2008 Feb 14. Proc Natl Acad Sci U S A. 2008. PMID: 18287017 Free PMC article.
Aggravation of viral hepatitis by platelet-derived serotonin.
Lang PA, Contaldo C, Georgiev P, El-Badry AM, Recher M, Kurrer M, Cervantes-Barragan L, Ludewig B, Calzascia T, Bolinger B, Merkler D, Odermatt B, Bader M, Graf R, Clavien PA, Hegazy AN, Löhning M, Harris NL, Ohashi PS, Hengartner H, Zinkernagel RM, Lang KS. Lang PA, et al. Among authors: calzascia t. Nat Med. 2008 Jul;14(7):756-61. doi: 10.1038/nm1780. Epub 2008 May 30. Nat Med. 2008. PMID: 18516052 Free article.
Deficiency of MALT1 paracaspase activity results in unbalanced regulatory and effector T and B cell responses leading to multiorgan inflammation.
Bornancin F, Renner F, Touil R, Sic H, Kolb Y, Touil-Allaoui I, Rush JS, Smith PA, Bigaud M, Junker-Walker U, Burkhart C, Dawson J, Niwa S, Katopodis A, Nuesslein-Hildesheim B, Weckbecker G, Zenke G, Kinzel B, Traggiai E, Brenner D, Brüstle A, St Paul M, Zamurovic N, McCoy KD, Rolink A, Régnier CH, Mak TW, Ohashi PS, Patel DD, Calzascia T. Bornancin F, et al. Among authors: calzascia t. J Immunol. 2015 Apr 15;194(8):3723-34. doi: 10.4049/jimmunol.1402254. Epub 2015 Mar 11. J Immunol. 2015. PMID: 25762782
A critical role for the innate immune signaling molecule IRAK-4 in T cell activation.
Suzuki N, Suzuki S, Millar DG, Unno M, Hara H, Calzascia T, Yamasaki S, Yokosuka T, Chen NJ, Elford AR, Suzuki J, Takeuchi A, Mirtsos C, Bouchard D, Ohashi PS, Yeh WC, Saito T. Suzuki N, et al. Among authors: calzascia t. Science. 2006 Mar 31;311(5769):1927-32. doi: 10.1126/science.1124256. Science. 2006. PMID: 16574867
37 results