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Sialyl Lewis(x)-mediated, PSGL-1-independent rolling adhesion on P-selectin.
Rodgers SD, Camphausen RT, Hammer DA. Rodgers SD, et al. Among authors: camphausen rt. Biophys J. 2000 Aug;79(2):694-706. doi: 10.1016/S0006-3495(00)76328-4. Biophys J. 2000. PMID: 10920004 Free PMC article.
Important contributions of P-selectin glycoprotein ligand-1-mediated secondary capture to human monocyte adhesion to P-selectin, E-selectin, and TNF-alpha-activated endothelium under flow in vitro.
Lim YC, Snapp K, Kansas GS, Camphausen R, Ding H, Luscinskas FW. Lim YC, et al. J Immunol. 1998 Sep 1;161(5):2501-8. J Immunol. 1998. PMID: 9725249
The N-terminal peptide of PSGL-1 can mediate adhesion to trauma-activated endothelium via P-selectin in vivo.
Burch EE, Shinde Patil VR, Camphausen RT, Kiani MF, Goetz DJ. Burch EE, et al. Among authors: camphausen rt. Blood. 2002 Jul 15;100(2):531-8. doi: 10.1182/blood.v100.2.531. Blood. 2002. PMID: 12091345
Beta-C-mannosides as selectin inhibitors.
Kaila N, Chen L, Thomas BE 4th, Tsao D, Tam S, Bedard PW, Camphausen RT, Alvarez JC, Ullas G. Kaila N, et al. Among authors: camphausen rt. J Med Chem. 2002 Apr 11;45(8):1563-6. doi: 10.1021/jm010390f. J Med Chem. 2002. PMID: 11931610
Interaction of P-selectin and PSGL-1 generates microparticles that correct hemostasis in a mouse model of hemophilia A.
Hrachovinov√° I, Cambien B, Hafezi-Moghadam A, Kappelmayer J, Camphausen RT, Widom A, Xia L, Kazazian HH Jr, Schaub RG, McEver RP, Wagner DD. Hrachovinov√° I, et al. Among authors: camphausen rt. Nat Med. 2003 Aug;9(8):1020-5. doi: 10.1038/nm899. Epub 2003 Jul 13. Nat Med. 2003. PMID: 12858167
Quinic acid derivatives as sialyl Lewis(x)-mimicking selectin inhibitors: design, synthesis, and crystal structure in complex with E-selectin.
Kaila N, Somers WS, Thomas BE, Thakker P, Janz K, DeBernardo S, Tam S, Moore WJ, Yang R, Wrona W, Bedard PW, Crommie D, Keith JC Jr, Tsao DH, Alvarez JC, Ni H, Marchese E, Patton JT, Magnani JL, Camphausen RT. Kaila N, et al. Among authors: camphausen rt. J Med Chem. 2005 Jun 30;48(13):4346-57. doi: 10.1021/jm050049l. J Med Chem. 2005. PMID: 15974587
Rolling adhesion kinematics of yeast engineered to express selectins.
Bhatia SK, Swers JS, Camphausen RT, Wittrup KD, Hammer DA. Bhatia SK, et al. Among authors: camphausen rt. Biotechnol Prog. 2003 May-Jun;19(3):1033-7. doi: 10.1021/bp025756b. Biotechnol Prog. 2003. PMID: 12790675
Shear-dependent capping of L-selectin and P-selectin glycoprotein ligand 1 by E-selectin signals activation of high-avidity beta2-integrin on neutrophils.
Green CE, Pearson DN, Camphausen RT, Staunton DE, Simon SI. Green CE, et al. Among authors: camphausen rt. J Immunol. 2004 Jun 15;172(12):7780-90. doi: 10.4049/jimmunol.172.12.7780. J Immunol. 2004. PMID: 15187162 Free article.
Design and synthesis of sialyl Lewis x mimics as E-selectin inhibitors.
Kaila N, Thomas BE 4th, Thakker P, Alvarez JC, Camphausen RT, Crommie D. Kaila N, et al. Among authors: camphausen rt. Bioorg Med Chem Lett. 2001 Jan 22;11(2):151-5. doi: 10.1016/s0960-894x(00)00623-5. Bioorg Med Chem Lett. 2001. PMID: 11206447
Identification and structural determination of a potent P-selectin inhibitor.
Kaila N, Xu GY, Camphausen RT, Xiang Y. Kaila N, et al. Among authors: camphausen rt. Bioorg Med Chem. 2001 Mar;9(3):801-6. doi: 10.1016/s0968-0896(00)00298-4. Bioorg Med Chem. 2001. PMID: 11310615
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