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201 results

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Page 1
KLF5 controls glutathione metabolism to suppress p190-BCR-ABL+ B-cell lymphoblastic leukemia.
Zhang C, D'Alessandro A, Wellendorf AM, Mohmoud F, Serrano-Lopez J, Perentesis JP, Komurov K, Alexe G, Stegmaier K, Whitsett JA, Grimes HL, Cancelas JA. Zhang C, et al. Among authors: cancelas ja. Oncotarget. 2018 Jul 3;9(51):29665-29679. doi: 10.18632/oncotarget.25667. eCollection 2018 Jul 3. Oncotarget. 2018. PMID: 30038712 Free PMC article.
Vav3 collaborates with p190-BCR-ABL in lymphoid progenitor leukemogenesis, proliferation, and survival.
Chang KH, Sanchez-Aguilera A, Shen S, Sengupta A, Madhu MN, Ficker AM, Dunn SK, Kuenzi AM, Arnett JL, Santho RA, Agirre X, Perentesis JP, Deininger MW, Zheng Y, Bustelo XR, Williams DA, Cancelas JA. Chang KH, et al. Among authors: cancelas ja. Blood. 2012 Jul 26;120(4):800-11. doi: 10.1182/blood-2011-06-361709. Epub 2012 Jun 12. Blood. 2012. PMID: 22692505 Free PMC article.
Myeloid malignancies with chromosome 5q deletions acquire a dependency on an intrachromosomal NF-κB gene network.
Fang J, Barker B, Bolanos L, Liu X, Jerez A, Makishima H, Christie S, Chen X, Rao DS, Grimes HL, Komurov K, Weirauch MT, Cancelas JA, Maciejewski JP, Starczynowski DT. Fang J, et al. Among authors: cancelas ja. Cell Rep. 2014 Sep 11;8(5):1328-38. doi: 10.1016/j.celrep.2014.07.062. Epub 2014 Sep 4. Cell Rep. 2014. PMID: 25199827 Free PMC article.
p62 is required for stem cell/progenitor retention through inhibition of IKK/NF-κB/Ccl4 signaling at the bone marrow macrophage-osteoblast niche.
Chang KH, Sengupta A, Nayak RC, Duran A, Lee SJ, Pratt RG, Wellendorf AM, Hill SE, Watkins M, Gonzalez-Nieto D, Aronow BJ, Starczynowski DT, Civitelli R, Diaz-Meco MT, Moscat J, Cancelas JA. Chang KH, et al. Among authors: cancelas ja. Cell Rep. 2014 Dec 24;9(6):2084-97. doi: 10.1016/j.celrep.2014.11.031. Epub 2014 Dec 18. Cell Rep. 2014. PMID: 25533346 Free PMC article.
Vasculopathy-associated hyperangiotensinemia mobilizes haematopoietic stem cells/progenitors through endothelial AT₂R and cytoskeletal dysregulation.
Chang KH, Nayak RC, Roy S, Perumbeti A, Wellendorf AM, Bezold KY, Pirman M, Hill SE, Starnes J, Loberg A, Zhou X, Inagami T, Zheng Y, Malik P, Cancelas JA. Chang KH, et al. Among authors: cancelas ja. Nat Commun. 2015 Jan 9;6:5914. doi: 10.1038/ncomms6914. Nat Commun. 2015. PMID: 25574809 Free PMC article.
Pathogenesis of ELANE-mutant severe neutropenia revealed by induced pluripotent stem cells.
Nayak RC, Trump LR, Aronow BJ, Myers K, Mehta P, Kalfa T, Wellendorf AM, Valencia CA, Paddison PJ, Horwitz MS, Grimes HL, Lutzko C, Cancelas JA. Nayak RC, et al. Among authors: cancelas ja. J Clin Invest. 2015 Aug 3;125(8):3103-16. doi: 10.1172/JCI80924. Epub 2015 Jul 20. J Clin Invest. 2015. PMID: 26193632 Free PMC article. Clinical Trial.
201 results