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Axl and Mertk receptors cooperate to promote breast cancer progression by combined oncogenic signaling and evasion of host anti-tumor immunity.
Davra V, Kumar S, Geng K, Calianese D, Mehta D, Gadiyar V, Kasikara C, Lahey KC, Chang YJ, Wichroski M, Gao C, De Lorenzo MS, Kotenko SV, Bergsbaken T, Mishra PK, Gause WC, Quigley M, Spires TE, Birge RB. Davra V, et al. Cancer Res. 2020 Nov 25:canres.2066.2020. doi: 10.1158/0008-5472.CAN-20-2066. Online ahead of print. Cancer Res. 2020. PMID: 33239426
EMT transcription factor ZEB1 represses the mutagenic POLθ-mediated end-joining pathway in breast cancers.
Prodhomme MK, Pommier RM, Franchet C, Fauvet F, Bergoglio V, Brousset P, Morel AP, Brunac AC, Devouassoux-Shisheboran M, Petrilli V, Moyret-Lalle C, Hoffmann JS, Puisieux A, Tissier A. Prodhomme MK, et al. Cancer Res. 2020 Nov 25:canres.2626.2020. doi: 10.1158/0008-5472.CAN-20-2626. Online ahead of print. Cancer Res. 2020. PMID: 33239429
Therapeutic Targeting of Metadherin Suppresses Colorectal and Lung Cancer Progression and Metastasis.
Shen M, Xie S, Rowicki M, Michel S, Wei Y, Hang X, Wan L, Lu X, Yuan M, Jin JF, Jaschinski F, Zhou T, Klar R, Kang Y. Shen M, et al. Cancer Res. 2020 Nov 25:canres.1876.2020. doi: 10.1158/0008-5472.CAN-20-1876. Online ahead of print. Cancer Res. 2020. PMID: 33239430
Nucleoporin 210 serves a key scaffold for SMARCB1 in liver cancer.
Hong SH, Son KH, Ha SY, Wi TI, Choi SK, Won JE, Han HD, Ro Y, Park YM, Eun JW, Nam SW, Han JW, Kang K, You JS. Hong SH, et al. Cancer Res. 2020 Nov 25:canres.0568.2020. doi: 10.1158/0008-5472.CAN-20-0568. Online ahead of print. Cancer Res. 2020. PMID: 33239431
Altered mitochondria functionality defines a metastatic cell state in lung cancer and creates an exploitable vulnerability.
Chuang CH, Dorsch M, Dujardin P, Silas S, Ueffing K, Hölken JM, Yang D, Winslow MM, Grüner BM. Chuang CH, et al. Cancer Res. 2020 Nov 25:canres.1865.2020. doi: 10.1158/0008-5472.CAN-20-1865. Online ahead of print. Cancer Res. 2020. PMID: 33239425
Hyal2 expression in tumor-associated myeloid cells mediates cancer-related inflammation in bladder cancer.
Dominguez Gutierrez PR, Kwenda EP, Donelan W, O'Malley P, Crispen PL, Kusmartsev S. Dominguez Gutierrez PR, et al. Cancer Res. 2020 Nov 25:canres.1144.2020. doi: 10.1158/0008-5472.CAN-20-1144. Online ahead of print. Cancer Res. 2020. PMID: 33239427
The cancer-associated ATM R3008H mutation reveals the link between ATM activation and its exchange.
Milanovic M, Houghton LM, Menolfi D, Lee JH, Yamamoto K, Li Y, Lee BJ, Xu J, Estes VM, Wang D, McKinnon PJ, Paull TT, Zha S. Milanovic M, et al. Cancer Res. 2020 Nov 25:canres.2447.2020. doi: 10.1158/0008-5472.CAN-20-2447. Online ahead of print. Cancer Res. 2020. PMID: 33239428
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