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Year Number of Results
1971 1
1977 1
1978 1
1979 2
1980 3
1983 2
1984 1
1988 1
1989 1
1991 2
1994 1
1996 1
1997 1
1998 1
2004 1
2005 1
2006 2
2007 1
2008 1
2009 1
2010 4
2011 3
2012 3
2014 1
2015 2
2016 4
2017 3
2018 5
2019 7
2020 1
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Page 1
Pot-Economy Autooxidative Condensation of 2-Aryl-2-lithio-1,3-dithianes
Vale JR, et al. J Org Chem 2018. Among authors: Candeias NR. PMID 29334462 Free PMC article.
Treatment of 2-aryl-1,3-dithianes with n-BuLi in the absence of any electrophile leads to condensation of three molecules of 1,3-dithianes and formation of highly functionalized α-thioether ketones orthothioesters in 51-89% yields upon air exposure. ...
Treatment of 2-aryl-1,3-dithianes with n-BuLi in the absence of any electrophile leads to condensation of three molecules of 1,3-dith …
Synthesis and biological screening for cytotoxic activity of N-substituted indolines and morpholines.
Doan P, et al. Eur J Med Chem 2016. Among authors: Candeias NR. PMID 27214140
Specifically, new indoline derivative N-(2-hydroxy-5-nitrophenyl(4'-methylphenyl)methyl)indoline exhibited effective cytotoxic activity, with an IC50 of ∼74 μM. ...Therefore, N-(2-hydroxy-5-nitrophenyl(4'-methylphenyl)methyl)indoline can be considered as a potential drug-lead compound towards the discovery of new anti-cancer agents....
Specifically, new indoline derivative N-(2-hydroxy-5-nitrophenyl(4'-methylphenyl)methyl)indoline exhibited effective cytotoxic activi …
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