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Cannabidiol-induced apoptosis in human leukemia cells: A novel role of cannabidiol in the regulation of p22phox and Nox4 expression.
McKallip RJ, Jia W, Schlomer J, Warren JW, Nagarkatti PS, Nagarkatti M. McKallip RJ, et al. Mol Pharmacol. 2006 Sep;70(3):897-908. doi: 10.1124/mol.106.023937. Epub 2006 Jun 5. Mol Pharmacol. 2006. PMID: 16754784
In the current study, we examined the effects of the nonpsychoactive cannabinoid, cannabidiol, on the induction of apoptosis in leukemia cells. Exposure of leukemia cells to cannabidiol led to cannabinoid receptor 2 (CB2)-mediated reduction in c …
In the current study, we examined the effects of the nonpsychoactive cannabinoid, cannabidiol, on the induction of apoptosis in le
Cannabidiol induced a contrasting pro-apoptotic effect between freshly isolated and precultured human monocytes.
Wu HY, Chang AC, Wang CC, Kuo FH, Lee CY, Liu DZ, Jan TR. Wu HY, et al. Toxicol Appl Pharmacol. 2010 Aug 1;246(3):141-7. doi: 10.1016/j.taap.2010.05.003. Epub 2010 May 21. Toxicol Appl Pharmacol. 2010. PMID: 20471992
It has been documented that cannabidiol (CBD) induced apoptosis in a variety of transformed cells, including lymphocytic and monocytic leukemias. ...By comparison, both cells were sensitive to doxorubicin-induced apoptosis. CBD significantly dim …
It has been documented that cannabidiol (CBD) induced apoptosis in a variety of transformed cells, including lymphocytic and m …