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Normal alveolar epithelial lining fluid contains high levels of glutathione.
Cantin AM, North SL, Hubbard RC, Crystal RG. Cantin AM, et al. J Appl Physiol (1985). 1987 Jul;63(1):152-7. doi: 10.1152/jappl.1987.63.1.152. J Appl Physiol (1985). 1987. PMID: 3040659
Oxidant-mediated epithelial cell injury in idiopathic pulmonary fibrosis.
Cantin AM, North SL, Fells GA, Hubbard RC, Crystal RG. Cantin AM, et al. J Clin Invest. 1987 Jun;79(6):1665-73. doi: 10.1172/JCI113005. J Clin Invest. 1987. PMID: 3034979 Free PMC article.
Augmentation of glutathione in the fluid lining the epithelium of the lower respiratory tract by directly administering glutathione aerosol.
Buhl R, Vogelmeier C, Critenden M, Hubbard RC, Hoyt RF Jr, Wilson EM, Cantin AM, Crystal RG. Buhl R, et al. Proc Natl Acad Sci U S A. 1990 Jun;87(11):4063-7. doi: 10.1073/pnas.87.11.4063. Proc Natl Acad Sci U S A. 1990. PMID: 2349219 Free PMC article.
Effect of glutathione aerosol on oxidant-antioxidant imbalance in idiopathic pulmonary fibrosis.
Borok Z, Buhl R, Grimes GJ, Bokser AD, Hubbard RC, Holroyd KJ, Roum JH, Czerski DB, Cantin AM, Crystal RG. Borok Z, et al. Lancet. 1991 Jul 27;338(8761):215-6. doi: 10.1016/0140-6736(91)90350-x. Lancet. 1991. PMID: 1676780
Systemic glutathione deficiency in symptom-free HIV-seropositive individuals.
Buhl R, Jaffe HA, Holroyd KJ, Wells FB, Mastrangeli A, Saltini C, Cantin AM, Crystal RG. Buhl R, et al. Lancet. 1989 Dec 2;2(8675):1294-8. doi: 10.1016/s0140-6736(89)91909-0. Lancet. 1989. PMID: 2574255
Glutathione and inflammatory disorders of the lung.
Cantin AM, B├ęgin R. Cantin AM, et al. Lung. 1991;169(3):123-38. doi: 10.1007/BF02714149. Lung. 1991. PMID: 1895776 Free PMC article. Review.
Glutathione deficiency and HIV.
Buhl R, Jaffe HA, Holroyd KJ, Wells FB, Mastrangeli A, Saltini C, Cantin AM, Crystal RG. Buhl R, et al. Lancet. 1990 Mar 3;335(8688):546. doi: 10.1016/0140-6736(90)90783-2. Lancet. 1990. PMID: 1968559 No abstract available.
Oxidants spontaneously released by alveolar macrophages of cigarette smokers can inactivate the active site of alpha 1-antitrypsin, rendering it ineffective as an inhibitor of neutrophil elastase.
Hubbard RC, Ogushi F, Fells GA, Cantin AM, Jallat S, Courtney M, Crystal RG. Hubbard RC, et al. J Clin Invest. 1987 Nov;80(5):1289-95. doi: 10.1172/JCI113204. J Clin Invest. 1987. PMID: 2824559 Free PMC article.
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