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Ras, PI(3)K and mTOR signalling controls tumour cell growth.
Shaw RJ, Cantley LC. Shaw RJ, et al. Among authors: cantley lc. Nature. 2006 May 25;441(7092):424-30. doi: 10.1038/nature04869. Nature. 2006. PMID: 16724053 Review.
SH2 domain specificity and activity modified by a single residue.
Marengere LE, Songyang Z, Gish GD, Schaller MD, Parsons JT, Stern MJ, Cantley LC, Pawson T. Marengere LE, et al. Among authors: cantley lc. Nature. 1994 Jun 9;369(6480):502-5. doi: 10.1038/369502a0. Nature. 1994. PMID: 7515480
Direct regulation of the Akt proto-oncogene product by phosphatidylinositol-3,4-bisphosphate.
Franke TF, Kaplan DR, Cantley LC, Toker A. Franke TF, et al. Among authors: cantley lc. Science. 1997 Jan 31;275(5300):665-8. doi: 10.1126/science.275.5300.665. Science. 1997. PMID: 9005852
Transformation of chicken cells by the gene encoding the catalytic subunit of PI 3-kinase.
Chang HW, Aoki M, Fruman D, Auger KR, Bellacosa A, Tsichlis PN, Cantley LC, Roberts TM, Vogt PK. Chang HW, et al. Among authors: cantley lc. Science. 1997 Jun 20;276(5320):1848-50. doi: 10.1126/science.276.5320.1848. Science. 1997. PMID: 9188528
A new pathway for synthesis of phosphatidylinositol-4,5-bisphosphate.
Rameh LE, Tolias KF, Duckworth BC, Cantley LC. Rameh LE, et al. Among authors: cantley lc. Nature. 1997 Nov 13;390(6656):192-6. doi: 10.1038/36621. Nature. 1997. PMID: 9367159
SRPK2: a differentially expressed SR protein-specific kinase involved in mediating the interaction and localization of pre-mRNA splicing factors in mammalian cells.
Wang HY, Lin W, Dyck JA, Yeakley JM, Songyang Z, Cantley LC, Fu XD. Wang HY, et al. Among authors: cantley lc. J Cell Biol. 1998 Feb 23;140(4):737-50. doi: 10.1083/jcb.140.4.737. J Cell Biol. 1998. PMID: 9472028 Free PMC article.
New insights into tumor suppression: PTEN suppresses tumor formation by restraining the phosphoinositide 3-kinase/AKT pathway.
Cantley LC, Neel BG. Cantley LC, et al. Proc Natl Acad Sci U S A. 1999 Apr 13;96(8):4240-5. doi: 10.1073/pnas.96.8.4240. Proc Natl Acad Sci U S A. 1999. PMID: 10200246 Free PMC article. Review.
A motif-based profile scanning approach for genome-wide prediction of signaling pathways.
Yaffe MB, Leparc GG, Lai J, Obata T, Volinia S, Cantley LC. Yaffe MB, et al. Among authors: cantley lc. Nat Biotechnol. 2001 Apr;19(4):348-53. doi: 10.1038/86737. Nat Biotechnol. 2001. PMID: 11283593
The PX domains of p47phox and p40phox bind to lipid products of PI(3)K.
Kanai F, Liu H, Field SJ, Akbary H, Matsuo T, Brown GE, Cantley LC, Yaffe MB. Kanai F, et al. Among authors: cantley lc. Nat Cell Biol. 2001 Jul;3(7):675-8. doi: 10.1038/35083070. Nat Cell Biol. 2001. PMID: 11433300
The phosphoinositide 3-kinase pathway.
Cantley LC. Cantley LC. Science. 2002 May 31;296(5573):1655-7. doi: 10.1126/science.296.5573.1655. Science. 2002. PMID: 12040186 Review.
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