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AP-1 and retromer play opposite roles in the trafficking of sortilin between the Golgi apparatus and the lysosomes.
Canuel M, Lefrancois S, Zeng J, Morales CR. Canuel M, et al. Biochem Biophys Res Commun. 2008 Feb 15;366(3):724-30. doi: 10.1016/j.bbrc.2007.12.015. Epub 2007 Dec 17. Biochem Biophys Res Commun. 2008. PMID: 18078806
Amyloid Precursor-like Protein 2 and Sortilin Do Not Regulate the PCSK9 Convertase-mediated Low Density Lipoprotein Receptor Degradation but Interact with Each Other.
Butkinaree C, Canuel M, Essalmani R, Poirier S, Benjannet S, Asselin MC, Roubtsova A, Hamelin J, Marcinkiewicz J, Chamberland A, Guillemot J, Mayer G, Sisodia SS, Jacob Y, Prat A, Seidah NG. Butkinaree C, et al. Among authors: canuel m. J Biol Chem. 2015 Jul 24;290(30):18609-20. doi: 10.1074/jbc.M115.647180. Epub 2015 Jun 17. J Biol Chem. 2015. PMID: 26085104 Free PMC article.
The proprotein convertase PC7: unique zymogen activation and trafficking pathways.
Rousselet E, Benjannet S, Hamelin J, Canuel M, Seidah NG. Rousselet E, et al. Among authors: canuel m. J Biol Chem. 2011 Jan 28;286(4):2728-38. doi: 10.1074/jbc.M110.192344. Epub 2010 Nov 12. J Biol Chem. 2011. PMID: 21075846 Free PMC article.
The interactomics of sortilin: an ancient lysosomal receptor evolving new functions.
Canuel M, Libin Y, Morales CR. Canuel M, et al. Histol Histopathol. 2009 Apr;24(4):481-92. doi: 10.14670/HH-24.481. Histol Histopathol. 2009. PMID: 19224451 Review.
Sortilin and prosaposin localize to detergent-resistant membrane microdomains.
Canuel M, Bhattacharyya N, Balbis A, Yuan L, Morales CR. Canuel M, et al. Exp Cell Res. 2009 Jan 15;315(2):240-7. doi: 10.1016/j.yexcr.2008.10.009. Epub 2008 Oct 22. Exp Cell Res. 2009. PMID: 18992238
Sortilin mediates the lysosomal targeting of cathepsins D and H.
Canuel M, Korkidakis A, Konnyu K, Morales CR. Canuel M, et al. Biochem Biophys Res Commun. 2008 Aug 22;373(2):292-7. doi: 10.1016/j.bbrc.2008.06.021. Epub 2008 Jun 16. Biochem Biophys Res Commun. 2008. PMID: 18559255
The lysosomal trafficking of sphingolipid activator proteins (SAPs) is mediated by sortilin.
Lefrancois S, Zeng J, Hassan AJ, Canuel M, Morales CR. Lefrancois S, et al. Among authors: canuel m. EMBO J. 2003 Dec 15;22(24):6430-7. doi: 10.1093/emboj/cdg629. EMBO J. 2003. PMID: 14657016 Free PMC article.
Inactivation of sortilin (a novel lysosomal sorting receptor) by dominant negative competition and RNA interference.
Lefrancois S, Canuel M, Zeng J, Morales CR. Lefrancois S, et al. Among authors: canuel m. Biol Proced Online. 2005;7:17-25. doi: 10.1251/bpo101. Epub 2005 Jan 25. Biol Proced Online. 2005. PMID: 15682222 Free PMC article.
The sorting and trafficking of lysosomal proteins.
Ni X, Canuel M, Morales CR. Ni X, et al. Among authors: canuel m. Histol Histopathol. 2006 Aug;21(8):899-913. doi: 10.14670/HH-21.899. Histol Histopathol. 2006. PMID: 16691542 Review.
Implication of the proprotein convertases in iron homeostasis: proprotein convertase 7 sheds human transferrin receptor 1 and furin activates hepcidin.
Guillemot J, Canuel M, Essalmani R, Prat A, Seidah NG. Guillemot J, et al. Among authors: canuel m. Hepatology. 2013 Jun;57(6):2514-24. doi: 10.1002/hep.26297. Epub 2013 May 15. Hepatology. 2013. PMID: 23390091
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