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A farnesyltransferase inhibitor prevents both the onset and late progression of cardiovascular disease in a progeria mouse model.
Capell BC, Olive M, Erdos MR, Cao K, Faddah DA, Tavarez UL, Conneely KN, Qu X, San H, Ganesh SK, Chen X, Avallone H, Kolodgie FD, Virmani R, Nabel EG, Collins FS. Capell BC, et al. Among authors: cao k. Proc Natl Acad Sci U S A. 2008 Oct 14;105(41):15902-7. doi: 10.1073/pnas.0807840105. Epub 2008 Oct 6. Proc Natl Acad Sci U S A. 2008. PMID: 18838683 Free PMC article.
Cardiovascular pathology in Hutchinson-Gilford progeria: correlation with the vascular pathology of aging.
Olive M, Harten I, Mitchell R, Beers JK, Djabali K, Cao K, Erdos MR, Blair C, Funke B, Smoot L, Gerhard-Herman M, Machan JT, Kutys R, Virmani R, Collins FS, Wight TN, Nabel EG, Gordon LB. Olive M, et al. Among authors: cao k. Arterioscler Thromb Vasc Biol. 2010 Nov;30(11):2301-9. doi: 10.1161/ATVBAHA.110.209460. Epub 2010 Aug 26. Arterioscler Thromb Vasc Biol. 2010. PMID: 20798379 Free PMC article.
Progeria: translational insights from cell biology.
Gordon LB, Cao K, Collins FS. Gordon LB, et al. Among authors: cao k. J Cell Biol. 2012 Oct 1;199(1):9-13. doi: 10.1083/jcb.201207072. J Cell Biol. 2012. PMID: 23027899 Free PMC article.
Mouse models of laminopathies.
Zhang H, Kieckhaefer JE, Cao K. Zhang H, et al. Among authors: cao k. Aging Cell. 2013 Feb;12(1):2-10. doi: 10.1111/acel.12021. Epub 2012 Nov 26. Aging Cell. 2013. PMID: 23095062 Review.
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