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130 results
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Measurement of plasma S-adenosylmethionine and S-adenosylhomocysteine as their fluorescent isoindoles.
Capdevila A, Wagner C. Capdevila A, et al. Anal Biochem. 1998 Nov 15;264(2):180-4. doi: 10.1006/abio.1998.2839. Anal Biochem. 1998. PMID: 9866680
A simple rapid immunoassay for S-adenosylhomocysteine in plasma.
Capdevila A, Burk RF, Freedman J, Frantzen F, Alfheim I, Wagner C. Capdevila A, et al. J Nutr Biochem. 2007 Dec;18(12):827-31. doi: 10.1016/j.jnutbio.2007.01.003. Epub 2007 May 16. J Nutr Biochem. 2007. PMID: 17509856 Free PMC article.
Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine.
Kerins DM, Koury MJ, Capdevila A, Rana S, Wagner C. Kerins DM, et al. Among authors: capdevila a. Am J Clin Nutr. 2001 Dec;74(6):723-9. doi: 10.1093/ajcn/74.6.723. Am J Clin Nutr. 2001. PMID: 11722952
Pancreatic exocrine secretion is blocked by inhibitors of methylation.
Capdevila A, Decha-Umphai W, Song KH, Borchardt RT, Wagner C. Capdevila A, et al. Arch Biochem Biophys. 1997 Sep 1;345(1):47-55. doi: 10.1006/abbi.1997.0249. Arch Biochem Biophys. 1997. PMID: 9281310
Isolated hypermethioninemia: measurements of S-adenosylmethionine and choline.
Mudd SH, Jenden DJ, Capdevila A, Roch M, Levy HL, Wagner C. Mudd SH, et al. Among authors: capdevila a. Metabolism. 2000 Dec;49(12):1542-7. doi: 10.1053/meta.2000.18521. Metabolism. 2000. PMID: 11145114
A glycine N-methyltransferase knockout mouse model for humans with deficiency of this enzyme.
Luka Z, Capdevila A, Mato JM, Wagner C. Luka Z, et al. Among authors: capdevila a. Transgenic Res. 2006 Jun;15(3):393-7. doi: 10.1007/s11248-006-0008-1. Transgenic Res. 2006. PMID: 16779654 Free PMC article.
The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women.
Davis SR, Quinlivan EP, Shelnutt KP, Maneval DR, Ghandour H, Capdevila A, Coats BS, Wagner C, Selhub J, Bailey LB, Shuster JJ, Stacpoole PW, Gregory JF 3rd. Davis SR, et al. Among authors: capdevila a. J Nutr. 2005 May;135(5):1040-4. doi: 10.1093/jn/135.5.1040. J Nutr. 2005. PMID: 15867278
Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women.
Davis SR, Quinlivan EP, Shelnutt KP, Ghandour H, Capdevila A, Coats BS, Wagner C, Shane B, Selhub J, Bailey LB, Shuster JJ, Stacpoole PW, Gregory JF 3rd. Davis SR, et al. Among authors: capdevila a. J Nutr. 2005 May;135(5):1045-50. doi: 10.1093/jn/135.5.1045. J Nutr. 2005. PMID: 15867279
Loss of the glycine N-methyltransferase gene leads to steatosis and hepatocellular carcinoma in mice.
Martínez-Chantar ML, Vázquez-Chantada M, Ariz U, Martínez N, Varela M, Luka Z, Capdevila A, Rodríguez J, Aransay AM, Matthiesen R, Yang H, Calvisi DF, Esteller M, Fraga M, Lu SC, Wagner C, Mato JM. Martínez-Chantar ML, et al. Among authors: capdevila a. Hepatology. 2008 Apr;47(4):1191-9. doi: 10.1002/hep.22159. Hepatology. 2008. PMID: 18318442 Free PMC article.
Glycine N-methyltransferase deficiency: a novel inborn error causing persistent isolated hypermethioninaemia.
Mudd SH, Cerone R, Schiaffino MC, Fantasia AR, Minniti G, Caruso U, Lorini R, Watkins D, Matiaszuk N, Rosenblatt DS, Schwahn B, Rozen R, LeGros L, Kotb M, Capdevila A, Luka Z, Finkelstein JD, Tangerman A, Stabler SP, Allen RH, Wagner C. Mudd SH, et al. Among authors: capdevila a. J Inherit Metab Dis. 2001 Aug;24(4):448-64. doi: 10.1023/a:1010577512912. J Inherit Metab Dis. 2001. PMID: 11596649
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